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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1icvFMNOxygen-insensitive NAD(P)H nitroreductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1icvFMNOxygen-insensitive NAD(P)H nitroreductase/1.000
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.620
1necFMNOxygen-insensitive NAD(P)H nitroreductase10.605
1kqbFMNOxygen-insensitive NAD(P)H nitroreductase/0.599
3x21FMNOxygen-insensitive NAD(P)H nitroreductase/0.598
1oonFMNOxygen-insensitive NAD(P)H nitroreductase/0.594
1kqdFMNOxygen-insensitive NAD(P)H nitroreductase/0.583
1ylrFMNOxygen-insensitive NAD(P)H nitroreductase/0.567
1oo5FMNOxygen-insensitive NAD(P)H nitroreductase/0.554
3x22FMNOxygen-insensitive NAD(P)H nitroreductase/0.553
1yluFMNOxygen-insensitive NAD(P)H nitroreductase/0.552
1ooqFMNOxygen-insensitive NAD(P)H nitroreductase/0.539
3ge6FMNNitroreductase/0.538
1ds7FMNOxygen-insensitive NAD(P)H nitroreductase/0.535
1kqcFMNOxygen-insensitive NAD(P)H nitroreductase/0.535
1ykiFMNOxygen-insensitive NAD(P)H nitroreductase/0.525
1vfrFMNMajor NAD(P)H-flavin oxidoreductase1.6.990.504
4qlyFMNEnone reductase CLA-ER/0.472
3pxvFMNNitroreductase/0.460
3qdlFMNOxygen-insensitive NADPH nitroreductase/0.443