Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ictT44Transthyretin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1ictT44Transthyretin/1.000
1sn5T3Transthyretin/0.511
1kgjFL8Transthyretin/0.498
1tz8DESTransthyretin/0.480
1ie4T44Transthyretin/0.477
3vthAPCCarbamoyltransferase/0.461
3zc3NAPFerredoxin--NADP reductase1.18.1.20.461
5eg3ACPFibroblast growth factor receptor 2/0.456
3wdlATP4-phosphopantoate--beta-alanine ligase6.3.2.360.452
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.449
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.448
2yxuATPPyridoxal kinase2.7.1.350.446
2c6eHPMAurora kinase A2.7.11.10.442
1sn0T44Transthyretin/0.441
3uoyNAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.440
3uozNAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.440