sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1i7m | CG | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1i7m | CG | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 1.000 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.621 | |
| 3dz4 | C8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.608 | |
| 1i7c | MGB | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.605 | |
| 3dz2 | A8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.593 | |
| 3h0w | N8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.576 | |
| 3dz6 | M8E | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.566 | |
| 3h0v | M2T | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.516 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.514 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.511 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.510 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.507 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.504 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.500 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.499 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.494 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.490 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.489 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.487 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.483 | |
| 2ejz | SAH | Diphthine synthase | / | 0.482 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.482 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.481 | |
| 4e32 | DWN | Methyltransferase | / | 0.481 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.479 | |
| 3irh | DTP | HD domain protein | / | 0.478 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.478 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.476 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.473 | |
| 3n71 | SFG | Histone-lysine N-methyltransferase Smyd1 | / | 0.473 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.472 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.471 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.471 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.471 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.470 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.470 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.469 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.469 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.469 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.469 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.468 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.468 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.468 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.467 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.467 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.467 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.467 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.467 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.467 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.466 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.466 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.466 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.466 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 3e4a | QIX | Insulin-degrading enzyme | 3.4.24.56 | 0.465 | |
| 3i7v | B4P | AP4A hydrolase | / | 0.465 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.464 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.464 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.464 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.464 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.464 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.464 | |
| 4dyn | 0MR | Nucleoprotein | / | 0.464 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.463 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.462 | |
| 1hi0 | GTP | RNA-directed RNA polymerase | 2.7.7.48 | 0.461 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4e2z | JHZ | Methyltransferase | / | 0.461 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.461 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.461 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.460 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.460 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.460 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.460 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.460 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.459 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.459 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.459 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.458 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.458 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.458 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 5d4v | YGP | Uncharacterized protein MJ0489 | / | 0.458 | |
| 1fml | RTL | Retinol dehydratase | / | 0.457 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.457 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.457 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.457 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.457 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.457 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.457 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.457 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4e2y | JHZ | Methyltransferase | / | 0.457 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.456 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.456 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.456 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.455 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1kru | IPT | Galactoside O-acetyltransferase | 2.3.1.18 | 0.455 | |
| 2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.455 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4hh4 | SAH | CcbJ | / | 0.455 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.454 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.454 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.454 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.454 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.454 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.454 | |
| 5dp2 | NAP | CurF | / | 0.454 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.453 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.453 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.453 | |
| 2qg4 | UGA | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.453 | |
| 3c1o | NAP | Eugenol synthase | / | 0.453 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.453 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.453 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.453 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.453 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.452 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.452 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.452 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.452 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.452 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.452 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.452 | |
| 3ou6 | SAM | SAM-dependent methyltransferase | / | 0.452 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.452 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.452 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4bpr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.452 | |
| 4c5o | FAD | Putative monooxygenase | / | 0.452 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.452 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.451 | |
| 2iwh | ANP | Elongation factor 3A | / | 0.451 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.451 | |
| 4bvn | P32 | Beta-1 adrenergic receptor | / | 0.451 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.451 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 2jgb | MGT | Eukaryotic translation initiation factor 4E type 2 | / | 0.450 | |
| 4amj | CVD | Beta-1 adrenergic receptor | / | 0.450 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.450 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.450 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.450 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.449 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.449 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2y1w | 849 | Histone-arginine methyltransferase CARM1 | / | 0.449 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.449 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4j7h | TRH | PCZA361.3 | / | 0.449 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.449 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.449 | |
| 4to5 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.449 | |
| 4xvy | SAH | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
| 5cfn | 2BA | Stimulator of interferon genes protein | / | 0.449 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.448 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.448 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.448 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.448 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.448 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
| 1lce | TMF | Thymidylate synthase | / | 0.447 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.447 | |
| 2ql6 | TIZ | Nicotinamide riboside kinase 1 | / | 0.447 | |
| 3ou7 | SAM | SAM-dependent methyltransferase | / | 0.447 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.446 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.446 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.446 | |
| 2y1x | 845 | Histone-arginine methyltransferase CARM1 | / | 0.446 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.446 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.446 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.446 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.445 | |
| 1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.445 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 3nlj | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 3nw3 | MU2 | Peptidoglycan recognition protein 1 | / | 0.445 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.445 | |
| 3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3s7b | NH5 | N-lysine methyltransferase SMYD2 | / | 0.445 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 4j7g | TRH | PCZA361.3 | / | 0.445 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.444 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.444 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
| 3fpd | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.444 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.444 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.444 | |
| 4xwt | U5P | Ribonuclease J | / | 0.444 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.443 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1uk0 | FRM | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.443 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.443 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 4lut | DCS | Alanine racemase | / | 0.443 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.442 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.442 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3voi | RCB | Glucanase | / | 0.442 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.442 | |
| 5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.442 | |
| 1bx0 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.441 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.441 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.441 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.441 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.441 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.441 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.440 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.440 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.440 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3ndj | JHZ | Methyltransferase | / | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.440 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.440 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.440 |