scPDB - Distribution of Binding site Similarity values of 1hyh entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1hyh	NAD	L-2-hydroxyisocaproate dehydrogenase

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1hyh	NAD	L-2-hydroxyisocaproate dehydrogenase	/	1.000
4l4s	NAI	L-lactate dehydrogenase A chain	1.1.1.27	0.476
2fn7	NAD	Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase	/	0.475
4wlu	NAD	Malate dehydrogenase, mitochondrial	1.1.1.37	0.472
4wlv	NAD	Malate dehydrogenase, mitochondrial	1.1.1.37	0.468
2a92	NAI	L-lactate dehydrogenase	/	0.467
5a1t	NAI	L-lactate dehydrogenase	/	0.467
4nd2	A3D	Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase	/	0.459
2aa3	AP0	L-lactate dehydrogenase	/	0.451
4nd4	NAD	Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase	/	0.449
4ajp	88N	L-lactate dehydrogenase A chain	1.1.1.27	0.441