Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1hov | I52 | 72 kDa type IV collagenase | 3.4.24.24 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1hov | I52 | 72 kDa type IV collagenase | 3.4.24.24 | 1.000 | |
| 3i7i | 518 | Collagenase 3 | 3.4.24 | 0.453 | |
| 3ts4 | EEG | Macrophage metalloelastase | 3.4.24.65 | 0.451 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.445 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.443 | |
| 3ljg | EEF | Macrophage metalloelastase | 3.4.24.65 | 0.443 |