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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1hovI5272 kDa type IV collagenase3.4.24.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1hovI5272 kDa type IV collagenase3.4.24.241.000
3i7i518Collagenase 33.4.240.453
3ts4EEGMacrophage metalloelastase3.4.24.650.451
1uttCP8Macrophage metalloelastase3.4.24.650.445
2wo8077Macrophage metalloelastase3.4.24.650.443
3ljgEEFMacrophage metalloelastase3.4.24.650.443