sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1gwn | GTP | Rho-related GTP-binding protein RhoE |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 1.000 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.642 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.536 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.520 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.519 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.512 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.511 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.505 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.504 | |
| 3oiv | GNP | GTPase HRas | / | 0.503 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.499 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.496 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.490 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.485 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.485 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.483 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.478 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.476 | |
| 2rge | GNP | GTPase HRas | / | 0.476 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.474 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.474 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.470 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.469 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.468 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.468 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.462 | |
| 4nyi | GNP | GTPase HRas | / | 0.461 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.461 | |
| 2c5l | GTP | GTPase HRas | / | 0.460 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.460 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.459 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.458 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.457 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.456 | |
| 4dsn | GCP | GTPase KRas | / | 0.456 | |
| 4dvg | GSP | Rho family GTPase | / | 0.456 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.453 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.450 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.449 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.449 | |
| 3tgp | GNP | GTPase HRas | / | 0.448 | |
| 4dlt | GNP | GTPase HRas | / | 0.447 | |
| 4xvq | GNP | GTPase HRas | / | 0.447 | |
| 3lbn | GNP | GTPase HRas | / | 0.446 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.445 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.445 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.444 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.443 | |
| 4nyj | GNP | GTPase HRas | / | 0.442 | |
| 3ddc | GNP | GTPase HRas | / | 0.441 | |
| 5cyp | GSP | Septin-9 | / | 0.441 |