Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1grhFADGlutathione reductase, mitochondrial1.8.1.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1grhFADGlutathione reductase, mitochondrial1.8.1.71.000
1grgFADGlutathione reductase, mitochondrial1.8.1.70.953
1greFADGlutathione reductase, mitochondrial1.8.1.70.900
3grsFADGlutathione reductase, mitochondrial1.8.1.70.858
4gr1FADGlutathione reductase, mitochondrial1.8.1.70.838
1graFADGlutathione reductase, mitochondrial1.8.1.70.836
1grbFADGlutathione reductase, mitochondrial1.8.1.70.731
1k4qFADGlutathione reductase, mitochondrial1.8.1.70.635
1gsnFADGlutathione reductase, mitochondrial1.8.1.70.611
1bwcFADGlutathione reductase, mitochondrial1.8.1.70.607
3dk8FADGlutathione reductase, mitochondrial1.8.1.70.595
3dk9FADGlutathione reductase, mitochondrial1.8.1.70.581
3dk4FADGlutathione reductase, mitochondrial1.8.1.70.572
3sqpFADGlutathione reductase, mitochondrial1.8.1.70.562
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.546
2v6oFADThioredoxin glutathione reductase/0.523
3dgzFADThioredoxin reductase 2, mitochondrial1.8.1.90.517
4kprFADThioredoxin reductase 1, cytoplasmic1.8.1.90.475
2r9zFADGlutathione amide reductase/0.472
2nvkFADThioredoxin reductase 1, mitochondrial1.8.1.90.467
2j3nFADThioredoxin reductase 1, cytoplasmic1.8.1.90.464
3djgFADGlutathione reductase, mitochondrial1.8.1.70.462
1gerFADGlutathione reductase1.8.1.70.459
2cfyFADThioredoxin reductase 1, cytoplasmic1.8.1.90.453
2rabFADGlutathione amide reductase/0.451