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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1gq2NAPNADP-dependent malic enzyme1.1.1.40

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1gq2NAPNADP-dependent malic enzyme1.1.1.401.000
1pj2NAINAD-dependent malic enzyme, mitochondrial1.1.1.380.572
1do8NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.567
1efkNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.551
1eflNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.549
1pj3NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.543
1gz4ATPNAD-dependent malic enzyme, mitochondrial1.1.1.380.533
1pj4ATPNAD-dependent malic enzyme, mitochondrial1.1.1.380.515
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.480
1e3eNAIAlcohol dehydrogenase 41.1.1.10.459
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.451
1rkxNADCDP-D-glucose-4,6-dehydratase/0.446
2yxuATPPyridoxal kinase2.7.1.350.443