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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1gaxVAAValine--tRNA ligase6.1.1.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1gaxVAAValine--tRNA ligase6.1.1.91.000
1ivsVAAValine--tRNA ligase6.1.1.90.657
3zgz84TLeucine--tRNA ligase/0.488
5kwvANPPantothenate synthetase/0.483
3coy53HPantothenate synthetase6.3.2.10.482
1n2iPAJPantothenate synthetase6.3.2.10.474
3ziuLSSLeucyl-tRNA synthetase/0.469
1n2hPAJPantothenate synthetase6.3.2.10.467
2ct8MSPMethionine--tRNA ligase6.1.1.100.465
3cow52HPantothenate synthetase6.3.2.10.461
1pfyMSPMethionine--tRNA ligase6.1.1.100.453
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.451
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.451
3ivxFG6Pantothenate synthetase6.3.2.10.450
3iocA5DPantothenate synthetase6.3.2.10.448
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.447
3ioeA7DPantothenate synthetase6.3.2.10.444
1jil485Tyrosine--tRNA ligase/0.443
3kt3TYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.441