sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 1.000 | |
| 1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.595 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.569 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.558 | |
| 4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.553 | |
| 2ovx | 4MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.551 | |
| 1sln | INH | Stromelysin-1 | 3.4.24.17 | 0.550 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.547 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.546 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.540 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.539 | |
| 1hv5 | RXP | Stromelysin-3 | 3.4.24 | 0.536 | |
| 1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.534 | |
| 3ljg | EEF | Macrophage metalloelastase | 3.4.24.65 | 0.534 | |
| 4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.533 | |
| 2xs3 | ALA_PHE_THR_SER | Karilysin | 3.4.24 | 0.526 | |
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.525 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.525 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.521 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.519 | |
| 1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.517 | |
| 2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.508 | |
| 2ow1 | 7MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.507 | |
| 1d5j | MM3 | Stromelysin-1 | 3.4.24.17 | 0.506 | |
| 2d1o | FA4 | Stromelysin-1 | 3.4.24.17 | 0.506 | |
| 3oho | Z79 | Stromelysin-1 | 3.4.24.17 | 0.505 | |
| 2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.502 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.497 | |
| 1hy7 | MBS | Stromelysin-1 | 3.4.24.17 | 0.493 | |
| 2xs4 | ALA_PHE_THR | Karilysin | 3.4.24 | 0.492 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.492 | |
| 4i03 | L88 | Macrophage metalloelastase | 3.4.24.65 | 0.492 | |
| 1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.490 | |
| 3kry | 3KR | Collagenase 3 | 3.4.24 | 0.490 | |
| 3i7g | 732 | Collagenase 3 | 3.4.24 | 0.489 | |
| 2wo8 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.484 | |
| 2hu6 | 37A | Macrophage metalloelastase | 3.4.24.65 | 0.483 | |
| 2wo9 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.483 | |
| 4h30 | 0ZD | Macrophage metalloelastase | 3.4.24.65 | 0.483 | |
| 2woa | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.481 | |
| 3tsk | QEG | Macrophage metalloelastase | 3.4.24.65 | 0.481 | |
| 2woa | 576 | Macrophage metalloelastase | 3.4.24.65 | 0.479 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.478 | |
| 4gr3 | R45 | Macrophage metalloelastase | 3.4.24.65 | 0.478 | |
| 1gkc | NFH | Matrix metalloproteinase-9 | 3.4.24.35 | 0.477 | |
| 2d1n | FA4 | Collagenase 3 | 3.4.24 | 0.477 | |
| 1fm1 | WAY | Collagenase 3 | 3.4.24 | 0.476 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.475 | |
| 2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.474 | |
| 1jk3 | BAT | Macrophage metalloelastase | 3.4.24.65 | 0.472 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.469 | |
| 4a7b | 3W4 | Collagenase 3 | 3.4.24 | 0.468 | |
| 1zs0 | EIN | Neutrophil collagenase | 3.4.24.34 | 0.464 | |
| 3kec | 3KE | Collagenase 3 | 3.4.24 | 0.464 | |
| 4guy | KLJ | Macrophage metalloelastase | 3.4.24.65 | 0.463 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.461 | |
| 1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.460 | |
| 2wo9 | 068 | Macrophage metalloelastase | 3.4.24.65 | 0.460 | |
| 3aig | 0ZC | Snake venom metalloproteinase adamalysin-2 | 3.4.24.46 | 0.460 | |
| 1rm8 | BAT | Matrix metalloproteinase-16 | 3.4.24 | 0.455 | |
| 1you | PFD | Collagenase 3 | 3.4.24 | 0.455 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.454 | |
| 1mnc | PLH | Neutrophil collagenase | 3.4.24.34 | 0.453 | |
| 1dth | BAT | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.451 | |
| 4h76 | 10B | Macrophage metalloelastase | 3.4.24.65 | 0.451 | |
| 2oy2 | ILE_ALA_GLY | Neutrophil collagenase | 3.4.24.34 | 0.443 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.440 |