Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1frb | ZST | Aldose reductase-related protein 2 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
1frb | ZST | Aldose reductase-related protein 2 | / | 1.000 | |
3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.459 | |
3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.457 | |
3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 |