sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1fm1 | WAY | Collagenase 3 | 3.4.24 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1fm1 | WAY | Collagenase 3 | 3.4.24 | 1.000 | |
| 1fls | WAY | Collagenase 3 | 3.4.24 | 0.616 | |
| 4i03 | L88 | Macrophage metalloelastase | 3.4.24.65 | 0.549 | |
| 2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.518 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.502 | |
| 1d5j | MM3 | Stromelysin-1 | 3.4.24.17 | 0.496 | |
| 1hv5 | RXP | Stromelysin-3 | 3.4.24 | 0.487 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.485 | |
| 2wo9 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.485 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.478 | |
| 4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.473 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.469 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.467 | |
| 4gr3 | R45 | Macrophage metalloelastase | 3.4.24.65 | 0.467 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.463 | |
| 2xs3 | ALA_PHE_THR_SER | Karilysin | 3.4.24 | 0.463 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.462 | |
| 2ovx | 4MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.460 | |
| 3aig | 0ZC | Snake venom metalloproteinase adamalysin-2 | 3.4.24.46 | 0.459 | |
| 2woa | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.457 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.455 | |
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.455 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.453 | |
| 2wo8 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.453 | |
| 2ow1 | 7MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.451 | |
| 2xs4 | ALA_PHE_THR | Karilysin | 3.4.24 | 0.451 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.451 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.451 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.451 | |
| 1pl2 | ABY | Glutathione S-transferase A1 | 2.5.1.18 | 0.449 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.447 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.447 | |
| 1jk3 | BAT | Macrophage metalloelastase | 3.4.24.65 | 0.444 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.444 | |
| 1b3d | S27 | Stromelysin-1 | 3.4.24.17 | 0.443 | |
| 3tsk | QEG | Macrophage metalloelastase | 3.4.24.65 | 0.443 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 4h76 | 10B | Macrophage metalloelastase | 3.4.24.65 | 0.441 | |
| 5ewj | QEL | NMDA glutamate receptor subunit | / | 0.440 | |
| 5ewj | QEL | Glutamate receptor ionotropic, NMDA 2B | / | 0.440 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.440 |