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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1fkjFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.8

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1fkjFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.81.000
1fkfFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.767
1bkfFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.723
1fkd818Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.678
2fkeFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.672
2dg3RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.658
1fklRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.649
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.635
4dh0MR8Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.631
1a7xFKAPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.627
4drm0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.623
2dg4RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.620
4dz2FK5Peptidyl-prolyl cis-trans isomerase/0.620
1j4hSUBPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.618
3o5rFK5Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.618
1c9hRAPPeptidyl-prolyl cis-trans isomerase FKBP1B5.2.1.80.615
4drn0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.615
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.613
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.613
1qpf858Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.608
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.608
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.607
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.607
1fkiSB1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.600
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.600
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.600
2dg9RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.599
1q6iFK5FKBP-type peptidyl-prolyl cis-trans isomerase FkpA5.2.1.80.593
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.588
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.588
4fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.588
4fapARDSerine/threonine-protein kinase mTOR2.7.11.10.588
4jfi1KTPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.588
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.586
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.586
1fkgSB3Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.581
4dro0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.577
4layI63Peptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.575
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.573
4drp0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.571
1fkhSBXPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.570
4drkI63Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.568
4qt3RAPPeptidylprolyl isomerase/0.561
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.531
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.531
3h3r14HCollagen type IV alpha-3-binding protein/0.528
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.523
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.518
5ah5LSSLeucine--tRNA ligase/0.510
3ju8NADN-succinylglutamate 5-semialdehyde dehydrogenase1.2.1.710.497
1u65CP0Acetylcholinesterase3.1.1.70.496
1eveE20Acetylcholinesterase3.1.1.70.495
1w4lGL8Acetylcholinesterase3.1.1.70.495
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.495
1h22E10Acetylcholinesterase3.1.1.70.494
2gyuHI6Acetylcholinesterase3.1.1.70.494
1vhzAPRADP compounds hydrolase NudE3.6.10.492
2avxHTFRegulatory protein SdiA/0.492
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.492
2j3qTFLAcetylcholinesterase3.1.1.70.491
3ivcFG4Pantothenate synthetase6.3.2.10.491
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.491
1lkeDOGBilin-binding protein/0.489
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.489
2ckmAA7Acetylcholinesterase3.1.1.70.489
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.489
1pfyMSPMethionine--tRNA ligase6.1.1.100.488
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.488
2ea2F77Methionine aminopeptidase 2/0.488
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.487
2ha6SCKAcetylcholinesterase3.1.1.70.487
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.487
1odcA8BAcetylcholinesterase3.1.1.70.486
4ey7E20Acetylcholinesterase3.1.1.70.486
2gg8U15Methionine aminopeptidase/0.485
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.485
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.484
1r58AO5Methionine aminopeptidase 2/0.483
2ggbU17Methionine aminopeptidase/0.483
3v0m5GWHisto-blood group ABO system transferase/0.483
2ga2A19Methionine aminopeptidase 2/0.482
2zs8ADPPantothenate kinase2.7.1.330.482
1r5gAO1Methionine aminopeptidase 2/0.481
2gywOBIAcetylcholinesterase3.1.1.70.481
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.481
1w6rGNTAcetylcholinesterase3.1.1.70.480
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.480
3g5iDNBPyrimidine-specific ribonucleoside hydrolase RihA/0.480
3vjlW94Dipeptidyl peptidase 4/0.480
3zv7NHGAcetylcholinesterase3.1.1.70.480
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.479
2gevCOKPantothenate kinase2.7.1.330.479
2whqHI6Acetylcholinesterase3.1.1.70.479
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.478
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.478
2qimZEAClass 10 plant pathogenesis-related protein/0.477
2xuiTZ5Acetylcholinesterase3.1.1.70.477
2xuoTZ4Acetylcholinesterase3.1.1.70.477
3i0oSMISpectinomycin phosphotransferase/0.477
3juoAJDPhenazine biosynthesis protein A/B/0.477
3mauEXTPutative sphingosine-1-phosphate lyase/0.477
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.476
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.476
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.476
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.476
1w76GNTAcetylcholinesterase3.1.1.70.476
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.476
2cekN8TAcetylcholinesterase3.1.1.70.476
2oazI96Methionine aminopeptidase 2/0.476
4bfuZVUPantothenate kinase2.7.1.330.476
4xba5GPAprataxin-like protein30.476
1el4CTZObelin/0.475
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.475
3e6eDCSAlanine racemase/0.475
3sfh1DIHistone deacetylase 83.5.1.980.475
3vjkM51Dipeptidyl peptidase 4/0.475
4ey6GNTAcetylcholinesterase3.1.1.70.475
4mm729JNa(+):neurotransmitter symporter (Snf family)/0.475
1lbm137N-(5'-phosphoribosyl)anthranilate isomerase5.3.1.240.474
2rqfJH3Hemolymph juvenile hormone binding protein/0.474
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.474
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.474
1gpnHUBAcetylcholinesterase3.1.1.70.473
2ct8MSPMethionine--tRNA ligase6.1.1.100.473
2jf0HBPAcetylcholinesterase3.1.1.70.473
3af1GDPPantothenate kinase2.7.1.330.473
4bfwZVWPantothenate kinase2.7.1.330.473
1amoFMNNADPH--cytochrome P450 reductase/0.472
1pqc444Oxysterols receptor LXR-beta/0.472
1qtiGNTAcetylcholinesterase3.1.1.70.472
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.472
4b63NAPL-ornithine N(5)-monooxygenase/0.472
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.471
1zgbA1EAcetylcholinesterase3.1.1.70.471
2gg9U16Methionine aminopeptidase/0.471
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3vilSA0Beta-glucosidase/0.471
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.471
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.471
1dx6GNTAcetylcholinesterase3.1.1.70.470
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.470
2q92B23Methionine aminopeptidase/0.470
2w6cBM4Acetylcholinesterase3.1.1.70.470
2xugTZ4Acetylcholinesterase3.1.1.70.470
3mauPLRPutative sphingosine-1-phosphate lyase/0.470
3myqE27Carbonic anhydrase 24.2.1.10.470
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.470
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.470
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.469
1r5hAO2Methionine aminopeptidase 2/0.469
1w6jR71Lanosterol synthase5.4.99.70.469
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.469
2gg2U12Methionine aminopeptidase/0.469
2xufTZ4Acetylcholinesterase3.1.1.70.469
3h59H59Genome polyprotein2.7.7.480.469
4b68NAPL-ornithine N(5)-monooxygenase/0.469
4b7zQ4QAcetylcholinesterase3.1.1.70.469
4jiq1L5GTN Reductase/0.469
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.468
1pj6FOLDimethylglycine oxidase1.5.3.100.468
2evcFC3Methionine aminopeptidase/0.468
2q94A04Methionine aminopeptidase/0.468
3iu9T07Methionine aminopeptidase 2/0.468
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.468
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.468
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.467
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.467
4cb593GPolymerase basic protein 2/0.467
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.467
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.466
1oz0MS1Bifunctional purine biosynthesis protein PURH2.1.2.30.466
1p0pBCHCholinesterase3.1.1.80.466
1s63778Protein farnesyltransferase subunit beta2.5.1.580.466
2gg3U13Methionine aminopeptidase/0.466
2pncCLUPrimary amine oxidase, liver isozyme/0.466
3pkaY02Methionine aminopeptidase 2/0.466
3pkeY10Methionine aminopeptidase 2/0.466
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.466
4arbC57Acetylcholinesterase3.1.1.70.466
4b64NAPL-ornithine N(5)-monooxygenase/0.466
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.466
4ykgFADAlkyl hydroperoxide reductase subunit F1.8.10.466
1rftPXMPyridoxal kinase2.7.1.350.465
2hp2KE4Glutamate-1-semialdehyde 2,1-aminomutase5.4.3.80.465
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.465
3c3xNAPEugenol synthase 11.1.1.3180.465
3elePLPAminotransferase/0.465
3iu8T03Methionine aminopeptidase 2/0.465
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
3mhcARZCarbonic anhydrase 24.2.1.10.465
4j0t6T9Beta-secretase 13.4.23.460.465
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.464
2cv2GSUGlutamate--tRNA ligase6.1.1.170.464
2q153MRBeta-secretase 13.4.23.460.464
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3v0p4GWHisto-blood group ABO system transferase/0.464
2aclL05Oxysterols receptor LXR-alpha/0.463
2aouCQAHistamine N-methyltransferase2.1.1.80.463
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.463
2jj8AZZDeoxynucleoside kinase/0.463
4isg1FYGlucokinase2.7.1.20.463
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.463
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.463
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.463
5brpPNGGlycoside Hydrolase Family 13/0.463
2zbwFADFerredoxin--NADP reductase/0.462
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.462
3q8uADPNucleoside diphosphate kinase/0.462
3sff0DIHistone deacetylase 83.5.1.980.462
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.462
4j4nD44Peptidylprolyl isomerase/0.462
5c3rHMUThymine dioxygenase/0.462
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.461
2xuhTZ4Acetylcholinesterase3.1.1.70.461
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.461
3nu03TUDihydrofolate reductase1.5.1.30.461
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.461
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.461
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.461
1vrqFMNSubunit alpha of sarocosine oxidase/0.460
1vrqFMNSubunit beta of sarcosine oxidase/0.460
2ea4F79Methionine aminopeptidase 2/0.460
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.460
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.460
4g8jTHMUridine phosphorylase/0.460
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.460
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.459
1votHUPAcetylcholinesterase3.1.1.70.459
2gbyBRNHTH-type transcriptional regulator QacR/0.459
2gg0U11Methionine aminopeptidase/0.459
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3f8sPF2Dipeptidyl peptidase 4/0.459
3g0gRUMDipeptidyl peptidase 4/0.459
4m0f1YKAcetylcholinesterase3.1.1.70.459
4mlp2CXCryptochrome-2/0.459
2xupTZ5Acetylcholinesterase3.1.1.70.458
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3fktSIIBeta-secretase 13.4.23.460.458
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.458
3wqmB29Diterpene synthase3.1.7.80.458
4a1oAMZBifunctional purine biosynthesis protein PurH2.1.2.30.458
4araC56Acetylcholinesterase3.1.1.70.458
4b66NAPL-ornithine N(5)-monooxygenase/0.458
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.458
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.458
4flkY10Methionine aminopeptidase 1/0.458
4relKMPGlycosyltransferase/0.458
7stdCRPScytalone dehydratase4.2.1.940.458
1c23MPHMethionine aminopeptidase/0.457
1oqmUD2Beta-1,4-galactosyltransferase 1/0.457
1pq944BOxysterols receptor LXR-beta/0.457
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.457
1yw9A84Methionine aminopeptidase 2/0.457
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.457
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.457
2lfoGCHFatty acid-binding protein, liver/0.457
3ccc7ACDipeptidyl peptidase 4/0.457
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.457
4fljY08Methionine aminopeptidase 1/0.457
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.457
1gaxVAAValine--tRNA ligase6.1.1.90.456
1j37X8ZAngiotensin-converting enzyme3.4.15.10.456
1mc0PCGcGMP-dependent 3',5'-cyclic phosphodiesterase/0.456
1rpwDIDHTH-type transcriptional regulator QacR/0.456
1zgaHMKIsoflavone 4'-O-methyltransferase/0.456
2nm2NEUDihydroneopterin aldolase/0.456
2p98YE7Methionine aminopeptidase/0.456
2v5uFMNFlavodoxin/0.456
2wcaNP6O-GlcNAcase BT_4395/0.456
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.456
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.456
3gncQQQGlutaryl-CoA dehydrogenase/0.456
3iu7FCDMethionine aminopeptidase 2/0.456
4e31JHZMethyltransferase/0.456
1ja1FMNNADPH--cytochrome P450 reductase/0.455
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.455
2dxdANPNucleoside diphosphate kinase2.7.4.60.455
2evmFC2Methionine aminopeptidase/0.455
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.455
3arpDEQChitinase A/0.455
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.455
3h3qH13Collagen type IV alpha-3-binding protein/0.455
4b4vL34Bifunctional protein FolD/0.455
4d2dALA_ALA_ALADi-or tripeptide:H+ symporter/0.455
4fllYZ6Methionine aminopeptidase 1/0.455
4kbyC2EStimulator of interferon genes protein/0.455
1ihiIU5Aldo-keto reductase family 1 member C2/0.454
1lnmDTXBilin-binding protein/0.454
1tg2H2BPhenylalanine-4-hydroxylase1.14.16.10.454
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.454
2a4xBLMMitomycin-binding protein/0.454
2aot2PMHistamine N-methyltransferase2.1.1.80.454
2flhZEACytokinin-specific binding protein/0.454
3af0GDPPantothenate kinase2.7.1.330.454
3gwfNAPCyclohexanone monooxygenase/0.454
3w3lRX8Toll-like receptor 8/0.454
4n3r2GUTankyrase-12.4.2.300.454
4s1iPLPPyridoxal kinase, putative/0.454
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
5p2pDHGPhospholipase A2, major isoenzyme3.1.1.40.454
1cnfFADNitrate reductase [NADH]1.7.1.10.453
1e66HUXAcetylcholinesterase3.1.1.70.453
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.453
2xjc5GPCytosolic purine 5'-nucleotidase3.1.3.50.453
3d27W29Methionine aminopeptidase/0.453
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.453
3fhxPLPPyridoxal kinase2.7.1.350.453
3sfy3FYUncharacterized protein/0.453
4jyzATPGlutamine--tRNA ligase6.1.1.180.453
1kw0H4BPhenylalanine-4-hydroxylase1.14.16.10.452
1ut6A8NAcetylcholinesterase3.1.1.70.452
1yw8A75Methionine aminopeptidase 2/0.452
1zdwFLVPrenyltransferase/0.452
2dxfGNPNucleoside diphosphate kinase2.7.4.60.452
2g1o2IGRenin3.4.23.150.452
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.452
2q96A18Methionine aminopeptidase/0.452
2xi4AFTAcetylcholinesterase3.1.1.70.452
2ydd2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
3lzzGDPUncharacterized protein/0.452
3nt5NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.452
3rsv3RSBeta-secretase 13.4.23.460.452
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.452
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.452
1jyw147Beta-galactosidase3.2.1.230.451
1pl1ABYGlutathione S-transferase A12.5.1.180.451
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.451
2gv8NDPThiol-specific monooxygenase1.14.130.451
3apwDP0Alpha-1-acid glycoprotein 2/0.451
3b4p3B4Phenazine biosynthesis protein A/B/0.451
3c8bARG_ARG_GLY_ILE_NH2Botulinum neurotoxin type A3.4.24.690.451
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.451
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3nt2NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.451
3pdqKC6Lysine-specific demethylase 4A1.14.110.451
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.451
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.451
4b4w9L9Bifunctional protein FolD/0.451
4la7A1OAbscisic acid receptor PYL2/0.451
4m4821BSodium-dependent dopamine transporter/0.451
1h60STRPentaerythritol tetranitrate reductase/0.450
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
2gl0ADNUncharacterized protein/0.450
2iyaZIOOleandomycin glycosyltransferase/0.450
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3i978DRNeuropilin-1/0.450
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3u4o08EGenome polyprotein2.7.7.480.450
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.450
4nv14TGFormyl transferase/0.450
1h36R88Squalene--hopene cyclase4.2.1.1290.449
1hfqMOTDihydrofolate reductase1.5.1.30.449
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.449
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2vatCOAAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.449
2wu4HBPAcetylcholinesterase3.1.1.70.449
3iwjNADAminoaldehyde dehydrogenase/0.449
3k8q22APurine nucleoside phosphorylase2.4.2.10.449
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.449
4bfzZVZPantothenate kinase2.7.1.330.449
4i1nFOLDihydrofolate reductase1.5.1.30.449
1ej3CZHAequorin-2/0.448
1lc3NADBiliverdin reductase A1.3.1.240.448
1xq04TRCarbonic anhydrase 24.2.1.10.448
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.448
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
2db3ANPATP-dependent RNA helicase vasa, isoform A3.6.4.130.448
2g1y5IGRenin3.4.23.150.448
2g247IGRenin3.4.23.150.448
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.448
3fw3ETSCarbonic anhydrase 44.2.1.10.448
3qbjNXZDipeptidyl peptidase 4/0.448
4es5MGTPolymerase basic protein 2/0.448
4hn1TYDdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.448
4j0v1H7Beta-secretase 13.4.23.460.448
4n9qFMNFMN-dependent NADH-azoreductase 1/0.448
4nqgCZHMitrocomin/0.448
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.448
5c8a5ADProbable transcriptional regulator/0.448
1acjTHAAcetylcholinesterase3.1.1.70.447
1gky5GPGuanylate kinase2.7.4.80.447
1h61PDNPentaerythritol tetranitrate reductase/0.447
1icqFMN12-oxophytodienoate reductase 11.3.1.420.447
1m13HYFNuclear receptor subfamily 1 group I member 2/0.447
1p8dCO1Oxysterols receptor LXR-beta/0.447
1w7gMIUProthrombin3.4.21.50.447
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.447
2vq7NAPPutative flavin-containing monooxygenase/0.447
2weaPP6Penicillopepsin-13.4.23.200.447
2x0yX0TO-GlcNAcase NagJ/0.447
2x7tWZBCarbonic anhydrase 24.2.1.10.447
3bk2U5PRibonuclease J/0.447
3c1oNAPEugenol synthase/0.447
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.447
3qt62P0Mevalonate diphosphate decarboxylase/0.447
3r8hZOMAldo-keto reductase family 1 member C3/0.447
4bz8J38Histone deacetylase/0.447
4gd40WSLysine-specific demethylase 4A1.14.110.447
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.447
4klaCHDFerrochelatase, mitochondrial4.99.1.10.447
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.447
5stdUNNScytalone dehydratase4.2.1.940.447
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.446
1by5GLY_GLY_GLY_AHO_AHO_AHO_FEFerrichrome-iron receptor/0.446
1culFOKAdenylate cyclase type 2/0.446
1culFOKAdenylate cyclase type 5/0.446
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1ja0FMNNADPH--cytochrome P450 reductase/0.446
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.446
1pq6965Oxysterols receptor LXR-beta/0.446
1umaIN2Prothrombin3.4.21.50.446
1x31FMNSubunit alpha of sarocosine oxidase/0.446
1x31FMNSubunit beta of sarcosine oxidase/0.446
2aj8SC3Dipeptidyl peptidase 4/0.446
2g21L1BRenin3.4.23.150.446
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.446
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.446
2j7dGI1Beta-glucosidase A3.2.1.210.446
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.446
2xukTZ5Acetylcholinesterase3.1.1.70.446
3c3eGDP2-phospho-L-lactate transferase/0.446
3mytEQUSteroid Delta-isomerase5.3.3.10.446
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.446
4hcy0YNTransketolase/0.446
4nv1TYDFormyl transferase/0.446
5fltVJJCarbonic anhydrase 24.2.1.10.446
6stdMS2Scytalone dehydratase4.2.1.940.446
4u163C0Muscarinic acetylcholine receptor M3/0.446
1cq6PY4Aspartate aminotransferase2.6.1.10.445
1cq8PY6Aspartate aminotransferase2.6.1.10.445
1dcyI3NPhospholipase A2, membrane associated/0.445
1h35R01Squalene--hopene cyclase4.2.1.1290.445
1jwtBLIProthrombin3.4.21.50.445
1mxfMTXPutative pteridine reductase 2/0.445
2a3bCFFEndochitinase B13.2.1.140.445
2aj4ANPGalactokinase2.7.1.60.445
2f6rACOBifunctional coenzyme A synthase/0.445
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.445
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.445
3oqfS51Renin3.4.23.150.445
3sxjSAMPutative methyltransferase/0.445
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.445
1lb9DNQGlutamate receptor 2/0.444
1obnASVIsopenicillin N synthase1.21.3.10.444
1qvtPRLHTH-type transcriptional regulator QacR/0.444
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1swgBTNStreptavidin/0.444
1tiqCOASpermidine/spermine N(1)-acetyltransferase/0.444
2aovC2MHistamine N-methyltransferase2.1.1.80.444
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.444
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.444
3ccbB2YDipeptidyl peptidase 4/0.444
3fp0FP015-O-acetyltransferase/0.444
3g0bT22Dipeptidyl peptidase 4/0.444
3kflME8Putative methionyl-tRNA synthetase/0.444
4jt91NSNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.444
4rp8ASCAscorbate-specific PTS system EIIC component/0.444
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
1a4wQWEProthrombin3.4.21.50.443
1db56INPhospholipase A2, membrane associated/0.443
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.443
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.443
1vftDCSAlanine racemase/0.443
1yw7A41Methionine aminopeptidase 2/0.443
2b1i93ABifunctional purine biosynthesis protein PURH2.1.2.30.443
2bn4FMNNADPH--cytochrome P450 reductase/0.443
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.443
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.443
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2v95HCYCorticosteroid-binding globulin/0.443
2vd7PD2Lysine-specific demethylase 4A1.14.110.443
2x3jATPAcsD/0.443
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
2zevIPEGeranylgeranyl pyrophosphate synthase/0.443
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3h3t16HCollagen type IV alpha-3-binding protein/0.443
3hl0NADMaleylacetate reductase/0.443
4ddhMS0Pantothenate synthetase6.3.2.10.443
4e2yJHZMethyltransferase/0.443
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.443
4psbGA3Cytokinin-specific binding protein/0.443
1t7o152Carnitine O-acetyltransferase2.3.1.70.442
1xvaSAMGlycine N-methyltransferase2.1.1.200.442
2dxiATPGlutamate--tRNA ligase6.1.1.170.442
2g1n1IGRenin3.4.23.150.442
2g1r3IGRenin3.4.23.150.442
2g1s4IGRenin3.4.23.150.442
2idvM7GEukaryotic translation initiation factor 4E-1/0.442
2nq7HM5Methionine aminopeptidase 1/0.442
2rehFADNitroalkane oxidase1.7.3.10.442
2wd2MS5Carbonic anhydrase 24.2.1.10.442
3ag6PAJPantothenate synthetase/0.442
3f90FMNFlavodoxin/0.442
3nd6ATPPhosphopantetheine adenylyltransferase/0.442
3rtnRTNBeta-secretase 13.4.23.460.442
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.442
3v0o4GWHisto-blood group ABO system transferase/0.442
3wgnGSPCell division protein FtsZ/0.442
4a16H34Acetylcholinesterase3.1.1.70.442
4c49HCYCorticosteroid-binding globulin/0.442
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3pblETQD(3) dopamine receptor/0.442
1ahgTYR_PLPAspartate aminotransferase2.6.1.10.441
1e7aPFLSerum albumin/0.441
1jf0CZHObelin/0.441
1queFADFerredoxin--NADP reductase1.18.1.20.441
1qv0CZHObelin/0.441
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.441
1umlFR4Adenosine deaminase3.5.4.40.441
1zg32HIIsoflavone 4'-O-methyltransferase/0.441
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.441
2ikuLIYRenin3.4.23.150.441
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.441
2tplHPPTyrosine phenol-lyase4.1.99.20.441
3ai0PNWBeta-glucosidase/0.441
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.441
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.441
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.441
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.441
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.441
4e2xTYDMethyltransferase/0.441
4iktTFVMethionine aminopeptidase 1/0.441
4j1k1HGBeta-secretase 13.4.23.460.441
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.441
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
4m0cFMNFMN-dependent NADH-azoreductase 1/0.441
1ivsVAAValine--tRNA ligase6.1.1.90.440
1kiaSAMGlycine N-methyltransferase2.1.1.200.440
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.440
1uhhCZPAequorin-2/0.440
1x2bSTXProline iminopeptidase3.4.11.50.440
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.440
2rgu356Dipeptidyl peptidase 4/0.440
2v9cMREFMN-dependent NADH-azoreductase 1/0.440
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3ipuO40Oxysterols receptor LXR-alpha/0.440
3kkzSAMUncharacterized protein/0.440
3l7gM44Xaa-Pro dipeptidase3.4.13.90.440
3mjrAC2Deoxycytidine kinase2.7.1.740.440
3nx2FERFerulic acid decarboxylase/0.440
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3wqtANPCell division protein FtsA/0.440
4a802ANMajor pollen allergen Bet v 1-A/0.440
4fm80UQBeta-secretase 13.4.23.460.440
4hr2ADPNucleoside diphosphate kinase/0.440
4nv10FXFormyl transferase/0.440