Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.62

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.621.000
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.676
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.521
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.516
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.495
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.487
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.468
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.464
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.463
1x8lOXRRetinol dehydratase/0.460
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.451
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.451
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.441