scPDB - Distribution of Binding site Similarity values of 1fd0 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1fd0	254	Retinoic acid receptor gamma

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1fd0	254	Retinoic acid receptor gamma	/	1.000
1fcx	184	Retinoic acid receptor gamma	/	0.722
2lbd	REA	Retinoic acid receptor gamma	/	0.669
4dm6	TTB	Retinoic acid receptor beta	/	0.645
1fcy	564	Retinoic acid receptor gamma	/	0.626
1exa	394	Retinoic acid receptor gamma	/	0.604
4dm8	REA	Retinoic acid receptor beta	/	0.598
1xdk	REA	Retinoic acid receptor beta	/	0.584
1iyz	NDP	Probable quinone oxidoreductase	/	0.503
3t8x	T8X	T-cell surface glycoprotein CD1b	/	0.502
3tda	PN0	Cytochrome P450 2D6	/	0.498
4j6d	TES	Cytochrome P450 monooxygenase	/	0.492
2cul	FAD	GidA-related protein	/	0.491
3qm4	PN0	Cytochrome P450 2D6	/	0.489
2fs4	PZ1	Renin	3.4.23.15	0.485
3aba	FLI	Cytochrome P450	/	0.481
4j6c	STR	Cytochrome P450 monooxygenase	/	0.480
1xu7	CPS	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.478
4jbt	ASD	Cytochrome P450 monooxygenase	/	0.474
1q5d	EPB	Epothilone C/D epoxidase	1.14	0.473
2g26	3LG	Renin	3.4.23.15	0.473
1h36	R88	Squalene--hopene cyclase	4.2.1.129	0.472
2prh	238	Dihydroorotate dehydrogenase (quinone), mitochondrial	1.3.5.2	0.472
2yki	YKI	Heat shock protein HSP 90-alpha	/	0.472
3dl9	V2H	Vitamin D 25-hydroxylase	/	0.472
3eml	ZMA	Adenosine receptor A2a	/	0.472
4ele	31I	Dihydrofolate reductase	/	0.471
3p6m	DSO	Camphor 5-monooxygenase	1.14.15.1	0.470
3d3e	D3E	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.468
2j9l	ATP	H(+)/Cl(-) exchange transporter 5	/	0.467
3oq1	3OQ	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.467
3p6o	ETG	Camphor 5-monooxygenase	1.14.15.1	0.467
3up0	D7S	aceDAF-12	/	0.467
4iaq	2GM	5-hydroxytryptamine receptor 1B	/	0.466
1pkf	EPD	Epothilone C/D epoxidase	1.14	0.465
1xuo	LA1	Integrin alpha-L	/	0.465
2e99	B08	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.465
2ykj	YKJ	Heat shock protein HSP 90-alpha	/	0.465
3a1l	2CC	Cytochrome P450	/	0.464
3ix9	MTX	Dihydrofolate reductase	1.5.1.3	0.464
1qip	GNB	Lactoylglutathione lyase	4.4.1.5	0.463
2rgj	FAD	Flavin-containing monooxygenase	/	0.463
2bkt	RPF	Renin	3.4.23.15	0.462
2fon	FAD	Acyl-coenzyme A oxidase	/	0.462
3jyn	NDP	Quinone oxidoreductase	/	0.462
4b8u	IBK	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	4.2.1.59	0.462
2e98	B29	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.461
2ntj	P1H	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.461
4bb5	HD2	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.461
4elb	34R	Dihydrofolate reductase	/	0.461
1h35	R01	Squalene--hopene cyclase	4.2.1.129	0.460
3is9	AC7	Gag-Pol polyprotein	2.7.7.49	0.460
1o6r	R19	Squalene--hopene cyclase	4.2.1.129	0.459
3g70	A5T	Renin	3.4.23.15	0.459
3up3	XCA	aceDAF-12	/	0.459
4j6b	PLO	Cytochrome P450 monooxygenase	/	0.459
5uvi	ZMA	Adenosine receptor A2a	/	0.459
2rjp	886	A disintegrin and metalloproteinase with thrombospondin motifs 4	3.4.24.82	0.458
3p6n	DSO	Camphor 5-monooxygenase	1.14.15.1	0.458
5k2b	ZMA	Adenosine receptor A2a	/	0.458
4dhy	S41	Glucokinase	2.7.1.2	0.456
2qjy	SMA	Cytochrome b	/	0.455
3p6p	A6B	Camphor 5-monooxygenase	1.14.15.1	0.455
1o6q	R17	Squalene--hopene cyclase	4.2.1.129	0.454
1ot7	CHC	Bile acid receptor	/	0.454
2bxn	IDB	Serum albumin	/	0.454
2dvl	FAD	Acyl-CoA dehydrogenase	/	0.454
3ctj	320	Hepatocyte growth factor receptor	2.7.10.1	0.454
3g6z	A7T	Renin	3.4.23.15	0.454
4eev	L1X	Hepatocyte growth factor receptor	2.7.10.1	0.454
5jtb	ZMA	Adenosine receptor A2a	/	0.454
4bb6	HD1	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.453
4qbj	NHM	Glycylpeptide N-tetradecanoyltransferase	2.3.1.97	0.453
5doz	NDP	JamJ	/	0.453
3gyu	DL7	Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily	/	0.452
4cav	MYA	Glycylpeptide N-tetradecanoyltransferase	2.3.1.97	0.452
5k2d	ZMA	Adenosine receptor A2a	/	0.452
1n4h	REA	Nuclear receptor ROR-beta	/	0.451
3fmz	2T1	Retinol-binding protein 4	/	0.451
3hxf	BD9	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.451
3q44	D50	M1 family aminopeptidase	3.4.11	0.451
3s41	S41	Glucokinase	2.7.1.2	0.451
4gmg	NAP	Yersiniabactin biosynthetic protein YbtU	/	0.451
5iu8	6DZ	Adenosine receptor A2a	/	0.451
3ol5	SAW	Camphor 5-monooxygenase	1.14.15.1	0.450
4c7k	NAP	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.450
2yiu	SMA	Cytochrome b	/	0.449
4fiz	CUE	17beta-hydroxysteroid dehydrogenase	/	0.449
5k2c	ZMA	Adenosine receptor A2a	/	0.449
1s7g	NAD	NAD-dependent protein deacylase 2	/	0.447
2aib	ERG	Beta-elicitin cinnamomin	/	0.447
2ykc	YKC	Heat shock protein HSP 90-alpha	/	0.447
3irx	UDR	Gag-Pol polyprotein	2.7.7.49	0.447
4i3v	NAD	Aldehyde dehydrogenase (NAD+)	/	0.447
2e48	FAD	D-amino-acid oxidase	1.4.3.3	0.446
2q4w	FAD	Cytokinin dehydrogenase 7	1.5.99.12	0.446
3ipu	O40	Oxysterols receptor LXR-alpha	/	0.446
3qlh	T27	Gag-Pol polyprotein	2.7.7.49	0.446
4elf	35I	Dihydrofolate reductase	/	0.446
4hw3	19G	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.446
4iar	ERM	5-hydroxytryptamine receptor 1B	/	0.446
1rf9	DBR	Camphor 5-monooxygenase	1.14.15.1	0.445
2xc3	RT8	Steroid C26-monooxygenase	1.14.13.141	0.445
3fco	IIG	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.445
3n61	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.445
3oad	LPO	Renin	3.4.23.15	0.445
3tm5	SFG	Uncharacterized protein	/	0.445
4yt5	H4M	H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338	/	0.445
3uzc	T4E	Adenosine receptor A2a	/	0.445
2xvf	FAD	Putative flavin-containing monooxygenase	/	0.444
2ykb	YKB	Heat shock protein HSP 90-alpha	/	0.444
3u8h	BHP	Phospholipase A2, membrane associated	/	0.444
4g31	0WH	Eukaryotic translation initiation factor 2-alpha kinase 3	2.7.11.1	0.444
1fwm	CB3	Thymidylate synthase	/	0.443
3gyt	DL4	Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily	/	0.443
3p9t	TCL	Repressor	/	0.443
3zky	WT4	Isopenicillin N synthase	1.21.3.1	0.443
5k2a	ZMA	Adenosine receptor A2a	/	0.443
1f8g	NAD	NAD(P) transhydrogenase subunit alpha part 1	1.6.1.2	0.442
2a4n	COA	Aac(6')-Ii protein	/	0.442
2g27	4LG	Renin	3.4.23.15	0.442
2qd4	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.442
3bxx	QUE	Dihydroflavonol 4-reductase	1.1.1.219	0.442
3k1w	BFX	Renin	3.4.23.15	0.442
3thr	C2F	Glycine N-methyltransferase	2.1.1.20	0.442
3vg9	ZMA	Adenosine receptor A2a	/	0.442
3wix	LC3	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.442
4g3j	VNT	Lanosterol 14-alpha-demethylase	/	0.442
4isk	1JY	Thymidylate synthase	/	0.442
5dp2	NAP	CurF	/	0.442
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.441
3kpk	FAD	Sulfide-quinone reductase	/	0.441
3pqb	VGP	Putative oxidoreductase	/	0.441
3qv1	NAD	Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic	1.2.1.13	0.441
3slk	NDP	Polyketide synthase extender module 2	/	0.441
4y6n	UPG	Glucosyl-3-phosphoglycerate synthase	2.4.1.266	0.441
5bp9	SAH	Putative methyltransferase protein	/	0.441
5irn	ADP	Nucleotide binding oligomerization domain containing 2	/	0.441
1brp	RTL	Retinol-binding protein 4	/	0.440
2azz	TCH	Phospholipase A2, major isoenzyme	3.1.1.4	0.440
4d03	NAP	Phenylacetone monooxygenase	1.14.13.92	0.440
4elb	34S	Dihydrofolate reductase	/	0.440
4ib4	ERM	5-hydroxytryptamine receptor 2B	/	0.440
4mfb	29T	Gag-Pol polyprotein	2.7.7.49	0.440
4mvh	2F5	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.440
5ab7	MLC	Nonspecific lipid-transfer protein, putative	/	0.440
3rey	XAC	Adenosine receptor A2a	/	0.440