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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1f20FADNitric oxide synthase, brain1.14.13.39

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1f20FADNitric oxide synthase, brain1.14.13.391.000
3ojxFADNADPH--cytochrome P450 reductase/0.531
1tllFADNitric oxide synthase, brain1.14.13.390.480
1ja1FADNADPH--cytochrome P450 reductase/0.478
4yafFADNADPH--cytochrome P450 reductase/0.461
1gvhFADFlavohemoprotein/0.459
2bf4FADNADPH--cytochrome P450 reductase/0.452
1j9zFADNADPH--cytochrome P450 reductase/0.451
4y9uFADNADPH--cytochrome P450 reductase/0.449
4y7cFADNADPH--cytochrome P450 reductase/0.446
2bpoFADNADPH--cytochrome P450 reductase/0.441
2gjlFMNNitronate monooxygenase1.13.12.160.440