sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 1.000 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.543 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.464 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.459 | |
| 1q0q | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.457 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 3s85 | LK0 | Gag-Pol polyprotein | / | 0.452 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.452 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.448 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.447 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 1bvg | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.446 | |
| 1c6y | MK1 | Protease | / | 0.445 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.445 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 5doz | NDP | JamJ | / | 0.444 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.443 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.443 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.441 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.440 |