Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1ez0 | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
1ez0 | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 1.000 | |
4pd6 | URI | Nucleoside permease | / | 0.521 | |
1xdd | AAY | Integrin alpha-L | / | 0.520 | |
2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.495 | |
2ed3 | SAH | Diphthine synthase | / | 0.491 | |
4qzu | RTL | Retinol-binding protein 2 | / | 0.491 | |
1x1c | SAH | C-20 methyltransferase | / | 0.490 | |
1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.489 | |
3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.489 | |
1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.488 | |
1a4z | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.486 | |
3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.486 | |
1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.485 | |
1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.480 | |
2ejz | SAH | Diphthine synthase | / | 0.480 | |
4jqh | 1MF | Alr2278 protein | / | 0.480 | |
1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.478 | |
2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.478 | |
1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.477 | |
2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.477 | |
4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.477 | |
3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.476 | |
2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.475 | |
3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.475 | |
5dp2 | NAP | CurF | / | 0.475 | |
4b4w | 9L9 | Bifunctional protein FolD | / | 0.474 | |
4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.474 | |
1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.473 | |
2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.473 | |
2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.473 | |
2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
4eqx | FAD | Coenzyme A disulfide reductase | / | 0.472 | |
4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.471 | |
4mlp | 2CX | Cryptochrome-2 | / | 0.471 | |
5c7h | NDP | Putative oxidoreductase | / | 0.471 | |
1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.470 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.470 | |
2ej2 | PPE | Branched-chain amino acid aminotransferase (IlvE) | / | 0.469 | |
3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.469 | |
3ixp | 834 | Ecdysone receptor | / | 0.469 | |
1s7n | COA | Acetyl transferase | / | 0.468 | |
1x8l | OXR | Retinol dehydratase | / | 0.468 | |
3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.468 | |
3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.468 | |
3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.468 | |
4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.468 | |
1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.467 | |
1ot7 | IU5 | Bile acid receptor | / | 0.467 | |
2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.467 | |
2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.467 | |
3d7k | D7K | Benzaldehyde lyase | / | 0.467 | |
1cqp | 803 | Integrin alpha-L | / | 0.466 | |
1r2j | FAD | FkbI | / | 0.466 | |
1svl | ADP | Large T antigen | 3.6.4 | 0.466 | |
4at0 | FAD | Possible succinate dehydrogenase | / | 0.466 | |
4iah | 1DX | Alr2278 protein | / | 0.466 | |
4j16 | NAP | NAD(P) transhydrogenase subunit beta | / | 0.466 | |
1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.465 | |
3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.465 | |
4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.465 | |
4b4v | L34 | Bifunctional protein FolD | / | 0.465 | |
4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.465 | |
4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
1f4g | TP4 | Thymidylate synthase | / | 0.464 | |
1qor | NDP | Quinone oxidoreductase 1 | / | 0.464 | |
2gvd | FKP | Adenylate cyclase type 2 | / | 0.464 | |
2gvd | FKP | Adenylate cyclase type 5 | / | 0.464 | |
2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.464 | |
2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.464 | |
3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.464 | |
3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.464 | |
4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.464 | |
4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.464 | |
1cbs | REA | Cellular retinoic acid-binding protein 2 | / | 0.463 | |
1f4f | TP3 | Thymidylate synthase | / | 0.463 | |
1ysl | COA | Hydroxymethylglutaryl-CoA synthase | 2.3.3.10 | 0.463 | |
2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
1uop | GLY_PHE_GLU_PRO | Prolyl endopeptidase | 3.4.21.26 | 0.462 | |
1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.462 | |
3sz0 | FAD | Sulfide-quinone reductase | / | 0.462 | |
3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.462 | |
4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.462 | |
4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.462 | |
4ozt | P1A | Ecdysone receptor, putative | / | 0.462 | |
4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
1cul | FOK | Adenylate cyclase type 2 | / | 0.461 | |
1cul | FOK | Adenylate cyclase type 5 | / | 0.461 | |
1jtu | LYB | Thymidylate synthase | / | 0.461 | |
1upw | 444 | Oxysterols receptor LXR-beta | / | 0.461 | |
2e8r | SAH | Diphthine synthase | / | 0.461 | |
3c15 | FOK | Adenylate cyclase type 2 | / | 0.461 | |
3c15 | FOK | Adenylate cyclase type 5 | / | 0.461 | |
3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.461 | |
3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.461 | |
1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.460 | |
1cjt | FOK | Adenylate cyclase type 2 | / | 0.460 | |
1cjt | FOK | Adenylate cyclase type 5 | / | 0.460 | |
1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.460 | |
4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.460 | |
1kt3 | RTL | Retinol-binding protein 4 | / | 0.459 | |
1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
2ele | SAH | Diphthine synthase | / | 0.459 | |
2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.459 | |
2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.459 | |
2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.459 | |
3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.459 | |
4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
4bb2 | STR | Corticosteroid-binding globulin | / | 0.459 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.458 | |
1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.458 | |
3biy | 01K | Histone acetyltransferase p300 | / | 0.458 | |
3l6j | Z90 | Alr2278 protein | / | 0.458 | |
4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.458 | |
1kzj | CB3 | Thymidylate synthase | / | 0.457 | |
1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.457 | |
2ign | FAD | Pyranose 2-oxidase | / | 0.457 | |
3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.457 | |
4mfp | COA | Uncharacterized protein | / | 0.457 | |
4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.457 | |
5k2b | ZMA | Adenosine receptor A2a | / | 0.457 | |
1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
1kzi | THG | Thymidylate synthase | / | 0.456 | |
1tl7 | FOK | Adenylate cyclase type 2 | / | 0.456 | |
1tl7 | FOK | Adenylate cyclase type 5 | / | 0.456 | |
3eku | CY9 | Actin-5C | / | 0.456 | |
3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.456 | |
3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
3sxj | SAM | Putative methyltransferase | / | 0.456 | |
4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.456 | |
4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.456 | |
4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.456 | |
1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.455 | |
1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.455 | |
1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.455 | |
2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.455 | |
2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
3eks | CY9 | Actin-5C | / | 0.455 | |
4i8p | NAD | Aminoaldehyde dehydrogenase 1 | / | 0.455 | |
4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.455 | |
5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.455 | |
5fm7 | ADP | RuvB-like helicase | / | 0.455 | |
1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.454 | |
1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.454 | |
2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.454 | |
3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.454 | |
3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.454 | |
4b14 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.454 | |
4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.454 | |
4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.454 | |
4kqq | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.454 | |
5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.454 | |
1c7o | PPG | Hemolysin | / | 0.453 | |
1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.453 | |
1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.453 | |
1txt | CAA | HMG-CoA synthase | / | 0.453 | |
2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.453 | |
2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
2giv | ACO | Histone acetyltransferase KAT8 | / | 0.453 | |
2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.453 | |
2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.453 | |
3f63 | GTX | Glutathione transferase GST1-4 | / | 0.453 | |
3vtd | TKD | Vitamin D3 receptor | / | 0.453 | |
4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
1cs4 | FOK | Adenylate cyclase type 2 | / | 0.452 | |
1cs4 | FOK | Adenylate cyclase type 5 | / | 0.452 | |
1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.452 | |
1kux | CA3 | Serotonin N-acetyltransferase | / | 0.452 | |
1pk9 | 2FA | Purine nucleoside phosphorylase DeoD-type | / | 0.452 | |
1uoo | GLY_PHE_ARG_PRO | Prolyl endopeptidase | 3.4.21.26 | 0.452 | |
1ycf | FMN | Nitric oxide reductase | 1 | 0.452 | |
1zgv | 501 | Prothrombin | 3.4.21.5 | 0.452 | |
2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.452 | |
2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.452 | |
3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.452 | |
3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.452 | |
3up0 | D7S | aceDAF-12 | / | 0.452 | |
5k2c | ZMA | Adenosine receptor A2a | / | 0.452 | |
1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.451 | |
2dsh | SAH | Diphthine synthase | / | 0.451 | |
3e8x | NAP | BH1520 protein | / | 0.451 | |
3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.451 | |
4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.451 | |
4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
4qe6 | JN3 | Bile acid receptor | / | 0.451 | |
4ruj | VDX | Vitamin D3 receptor A | / | 0.451 | |
5c1m | CLR | Mu-type opioid receptor | / | 0.451 | |
5iub | CLR | Adenosine receptor A2a | / | 0.451 | |
5iu8 | 6DZ | Adenosine receptor A2a | / | 0.451 | |
1d4p | BPP | Prothrombin | 3.4.21.5 | 0.450 | |
1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.450 | |
2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.450 | |
2egs | SAH | Diphthine synthase | / | 0.450 | |
2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.450 | |
2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.450 | |
2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.450 | |
2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
3bgx | MEF | Thymidylate synthase | / | 0.450 | |
3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.450 | |
3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.450 | |
3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.450 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
4q0k | GA3 | Phytohormone-binding protein | / | 0.450 | |
4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.450 | |
1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.449 | |
1kvo | OAP | Phospholipase A2, membrane associated | / | 0.449 | |
1n1e | NDE | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.449 | |
1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.449 | |
1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
2p5f | SAH | Diphthine synthase | / | 0.449 | |
2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.449 | |
2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
2wdz | NAD | Galactitol dehydrogenase | / | 0.449 | |
3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.449 | |
3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.449 | |
3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.449 | |
3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.449 | |
3w55 | 1FM | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.449 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.449 | |
1e80 | 0GQ | Endothiapepsin | 3.4.23.22 | 0.448 | |
1fmj | RTL | Retinol dehydratase | / | 0.448 | |
1jwt | BLI | Prothrombin | 3.4.21.5 | 0.448 | |
1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.448 | |
2dv3 | SAH | Diphthine synthase | / | 0.448 | |
2pch | SAH | Diphthine synthase | / | 0.448 | |
3c14 | FOK | Adenylate cyclase type 2 | / | 0.448 | |
3c14 | FOK | Adenylate cyclase type 5 | / | 0.448 | |
3cnd | FAD | Polyamine oxidase FMS1 | / | 0.448 | |
3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.448 | |
3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
3kpk | FAD | Sulfide-quinone reductase | / | 0.448 | |
3muo | ZPR | Prolyl endopeptidase | / | 0.448 | |
3ngu | ADP | Nucleoside diphosphate kinase | / | 0.448 | |
3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.448 | |
3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.448 | |
4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.448 | |
4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
4kby | C2E | Stimulator of interferon genes protein | / | 0.448 | |
4u8i | FDA | UDP-galactopyranose mutase | / | 0.448 | |
4zow | CLM | Multidrug transporter MdfA | / | 0.448 | |
1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.447 | |
1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.447 | |
1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.447 | |
1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
1oyt | FSN | Prothrombin | 3.4.21.5 | 0.447 | |
1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
1trg | CB3 | Thymidylate synthase | / | 0.447 | |
1tys | DHF | Thymidylate synthase | / | 0.447 | |
1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.447 | |
2e07 | SAH | Diphthine synthase | / | 0.447 | |
2e7r | SAH | Diphthine synthase | / | 0.447 | |
2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.447 | |
2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.447 | |
3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.447 | |
4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.447 | |
4eiy | ZMA | Adenosine receptor A2a | / | 0.447 | |
4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.447 | |
4l4x | NDP | AmphI | / | 0.447 | |
4l8u | 9AZ | Serum albumin | / | 0.447 | |
3qak | UKA | Adenosine receptor A2a | / | 0.447 | |
1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.446 | |
1kqw | RTL | Cellular retinol-binding protein type II | / | 0.446 | |
1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
1u0h | FOK | Adenylate cyclase type 2 | / | 0.446 | |
1u0h | FOK | Adenylate cyclase type 5 | / | 0.446 | |
1uxv | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
2eck | ADP | Adenylate kinase | / | 0.446 | |
2owk | SAH | Diphthine synthase | / | 0.446 | |
2pks | G44 | Prothrombin | 3.4.21.5 | 0.446 | |
2vke | TAC | Tetracycline repressor protein class D | / | 0.446 | |
2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.446 | |
3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.446 | |
3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
4eb4 | D16 | Thymidylate synthase | 2.1.1.45 | 0.446 | |
4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.446 | |
4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.446 | |
1fwm | CB3 | Thymidylate synthase | / | 0.445 | |
1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.445 | |
1osv | CHC | Bile acid receptor | / | 0.445 | |
2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.445 | |
2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.445 | |
2g1n | 1IG | Renin | 3.4.23.15 | 0.445 | |
2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
2hq9 | FAD | Mll6688 protein | / | 0.445 | |
2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
2r0c | FAD | Putative FAD-monooxygenase | / | 0.445 | |
2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.445 | |
3b70 | NAP | Enoyl reductase LovC | 1 | 0.445 | |
3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.445 | |
4ap1 | NAP | Steroid monooxygenase | / | 0.445 | |
4cox | IMN | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.445 | |
4irn | FAD | AnaB | / | 0.445 | |
3eml | ZMA | Adenosine receptor A2a | / | 0.445 | |
1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.444 | |
1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.444 | |
1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.444 | |
1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.444 | |
2e4n | SAH | Diphthine synthase | / | 0.444 | |
2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.444 | |
2fr3 | REA | Cellular retinoic acid-binding protein 2 | / | 0.444 | |
2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
2zda | 32U | Prothrombin | 3.4.21.5 | 0.444 | |
3a1l | 2CC | Cytochrome P450 | / | 0.444 | |
3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.444 | |
3iae | D7K | Benzaldehyde lyase | / | 0.444 | |
3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
3n71 | SFG | Histone-lysine N-methyltransferase Smyd1 | / | 0.444 | |
3tda | PN0 | Cytochrome P450 2D6 | / | 0.444 | |
3vt6 | 5YI | Vitamin D3 receptor | / | 0.444 | |
4a2a | ATP | Cell division protein FtsA | / | 0.444 | |
4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.444 | |
4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.444 | |
4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.444 | |
4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.444 | |
4iae | 1DX | Alr2278 protein | / | 0.444 | |
4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.444 | |
4n6h | EJ4 | Delta-type opioid receptor | / | 0.444 | |
5k2d | ZMA | Adenosine receptor A2a | / | 0.444 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.443 | |
1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
2gci | MRR | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.443 | |
2ohi | FMN | Type A flavoprotein FprA | 1 | 0.443 | |
2yj5 | ATP | Copper-transporting ATPase | / | 0.443 | |
3cnt | FAD | Polyamine oxidase FMS1 | / | 0.443 | |
3coz | 54H | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
3jzd | NAD | Maleylacetate reductase | / | 0.443 | |
3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.443 | |
3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.443 | |
4fhh | 0U3 | Vitamin D3 receptor A | / | 0.443 | |
4fqs | LYA | Thymidylate synthase ThyA | / | 0.443 | |
4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.443 | |
4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
4ysh | FAD | Glycine oxidase | / | 0.443 | |
5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.443 | |
5bn3 | ADP | NEQ263 | / | 0.443 | |
1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.442 | |
1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.442 | |
1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.442 | |
1kfb | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
2anm | CDO | Prothrombin | 3.4.21.5 | 0.442 | |
2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
2p3b | 3TL | V-1 PROTEASE protein | / | 0.442 | |
2p3b | 3TL | V-1 protease | / | 0.442 | |
2pcg | SAH | Diphthine synthase | / | 0.442 | |
2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.442 | |
4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.442 | |
4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.442 | |
4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
4r7u | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
4u8k | FDA | UDP-galactopyranose mutase | / | 0.442 | |
5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.442 | |
5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.442 | |
5uvi | ZMA | Adenosine receptor A2a | / | 0.442 | |
1cjk | FOK | Adenylate cyclase type 2 | / | 0.441 | |
1cjk | FOK | Adenylate cyclase type 5 | / | 0.441 | |
1fvp | FMA | Non-fluorescent flavoprotein | / | 0.441 | |
1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
1k7f | IAV | Tryptophan synthase alpha chain | / | 0.441 | |
1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
1svm | ATP | Large T antigen | 3.6.4 | 0.441 | |
1x1b | SAH | C-20 methyltransferase | / | 0.441 | |
2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.441 | |
2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.441 | |
2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.441 | |
2dv7 | SAH | Diphthine synthase | / | 0.441 | |
2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
2lfo | GCH | Fatty acid-binding protein, liver | / | 0.441 | |
2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
2xls | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
2yj4 | ATP | Copper-transporting ATPase | / | 0.441 | |
3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.441 | |
3b7d | CNI | Glutamate receptor 2 | / | 0.441 | |
3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.441 | |
3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.441 | |
3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.441 | |
3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.441 | |
3vg9 | ZMA | Adenosine receptor A2a | / | 0.441 | |
3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
4c4o | NAD | SADH | / | 0.441 | |
4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
4jv3 | N32 | Beta-ketoacyl synthase | / | 0.441 | |
4l9q | 9TP | Serum albumin | / | 0.441 | |
4n1g | CEI | Obelin | / | 0.441 | |
4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.441 | |
4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.441 | |
5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.441 | |
1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.440 | |
1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
1kt6 | RTL | Retinol-binding protein 4 | / | 0.440 | |
1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.440 | |
1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
1q3h | ANP | Cystic fibrosis transmembrane conductance regulator | / | 0.440 | |
1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.440 | |
1x1d | SAH | C-20 methyltransferase | / | 0.440 | |
2fxu | BID | Actin, alpha skeletal muscle | / | 0.440 | |
2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.440 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.440 | |
2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
2zhf | 49U | Prothrombin | 3.4.21.5 | 0.440 | |
3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.440 | |
3c27 | DKK | Prothrombin | 3.4.21.5 | 0.440 | |
3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
3fp0 | FP0 | 15-O-acetyltransferase | / | 0.440 | |
3gc5 | 2MQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
3hl0 | NAD | Maleylacetate reductase | / | 0.440 | |
3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.440 | |
3slk | NDP | Polyketide synthase extender module 2 | / | 0.440 | |
3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.440 | |
3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.440 | |
3vt4 | 5YI | Vitamin D3 receptor | / | 0.440 | |
4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.440 | |
4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.440 | |
4o7u | THF | Thymidylate synthase | / | 0.440 | |
5bp9 | SAH | Putative methyltransferase protein | / | 0.440 |