Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 1.000 | |
| 3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.593 | |
| 3dok | GWJ | Pol protein | / | 0.587 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.585 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.585 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.582 | |
| 3ffi | 3OB | Gag-Pol polyprotein | 2.7.7.49 | 0.580 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.572 | |
| 3dmj | GWE | Pol protein | / | 0.570 | |
| 1s1v | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.568 | |
| 3t1a | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.567 | |
| 3dol | GWI | Pol protein | / | 0.564 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.558 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.557 | |
| 4rw4 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.554 | |
| 1klm | SPP | Gag-Pol polyprotein | 2.7.7.49 | 0.553 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.553 | |
| 3di6 | PDZ | Gag-Pol polyprotein | 2.7.7.49 | 0.552 | |
| 3i0s | RT7 | Gag-Pol polyprotein | 2.7.7.49 | 0.549 | |
| 1jla | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.545 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.544 | |
| 4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.544 | |
| 3drp | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.542 | |
| 1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.532 | |
| 1c1c | 612 | Gag-Pol polyprotein | 2.7.7.49 | 0.530 | |
| 3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.529 | |
| 1rt1 | MKC | Gag-Pol polyprotein | 2.7.7.49 | 0.528 | |
| 2rki | TT1 | Gag-Pol polyprotein | 2.7.7.49 | 0.527 | |
| 3e01 | PZ2 | Gag-Pol polyprotein | 2.7.7.49 | 0.527 | |
| 1rt2 | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.522 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.522 | |
| 3t19 | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.522 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.521 | |
| 3tam | M06 | Gag-Pol polyprotein | 2.7.7.49 | 0.520 | |
| 5cyq | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.518 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.516 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.514 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.512 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.505 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.504 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.502 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.496 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.493 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.492 | |
| 1eet | BFU | Gag-Pol polyprotein | 2.7.7.49 | 0.490 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.489 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.488 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.487 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.487 | |
| 4iah | 1DX | Alr2278 protein | / | 0.486 | |
| 2ynh | EUR | Gag-Pol polyprotein | 2.7.7.49 | 0.485 | |
| 1rev | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.483 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.483 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.482 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.481 | |
| 1hni | AAA | Gag-Pol polyprotein | 2.7.7.49 | 0.480 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.480 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.479 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.477 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.477 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.476 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.475 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.475 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 4ko0 | JLJ | Gag-Pol polyprotein | 2.7.7.49 | 0.475 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.474 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.473 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.473 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.472 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.471 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.471 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.471 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.471 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.470 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 1jut | LYD | Thymidylate synthase | / | 0.469 | |
| 3dlg | GWE | Gag-Pol polyprotein | 2.7.7.49 | 0.468 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.468 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.467 | |
| 3nbp | JGZ | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.467 | |
| 4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.467 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.467 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.466 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.465 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.464 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 2xvq | 9DS | Serum albumin | / | 0.464 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.464 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.463 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.463 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.463 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.463 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.463 | |
| 1s9e | ADB | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.462 | |
| 5a3b | APR | SIR2 family protein | / | 0.462 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.461 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.461 | |
| 2opq | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.461 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.460 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.460 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.460 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.459 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.459 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.459 | |
| 4pd6 | URI | Nucleoside permease | / | 0.459 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.459 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.458 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.458 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.458 | |
| 5ag6 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.457 | |
| 2oxt | SAM | Genome polyprotein | / | 0.457 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.457 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.457 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 1rt4 | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 1zdw | FLV | Prenyltransferase | / | 0.456 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.456 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.456 | |
| 3sh0 | SAX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.456 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.456 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.456 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.455 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2iut | AGS | DNA translocase FtsK | / | 0.455 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.455 | |
| 3zuy | TCH | Transporter | / | 0.455 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.455 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.454 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.454 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.454 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.454 | |
| 1ppj | SMA | Cytochrome b | / | 0.453 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.453 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.453 | |
| 4a2z | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 4iji | 99T | Glutathione S-transferase-like protein YibF | / | 0.453 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.452 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.452 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.452 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4b13 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.452 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.452 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 1pp9 | SMA | Cytochrome b | / | 0.451 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.451 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.451 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.451 | |
| 4c2z | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.451 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4l8u | 9AZ | Serum albumin | / | 0.451 | |
| 5ag7 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.450 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.450 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.450 | |
| 3bhh | 5CP | Calcium/calmodulin-dependent protein kinase type II subunit beta | 2.7.11.17 | 0.450 | |
| 3eld | SFG | Methyltransferase | / | 0.450 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.450 | |
| 3gcn | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.450 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.450 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.450 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.450 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.450 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 1ikw | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.449 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.449 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.449 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.449 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.448 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.448 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.448 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.448 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.448 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.447 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.447 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2bhe | BRY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.447 | |
| 4eb4 | D16 | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.447 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.447 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.446 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.446 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.446 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.446 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.446 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.446 | |
| 3zux | TCH | Transporter | / | 0.446 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.446 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.446 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.445 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.445 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.445 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.445 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.445 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.444 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 3q9y | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3r7v | Z02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.444 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.444 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.444 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.444 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.444 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 5ag5 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.444 | |
| 1an5 | CB3 | Thymidylate synthase | / | 0.443 | |
| 1e7a | PFL | Serum albumin | / | 0.443 | |
| 1n46 | PFA | Thyroid hormone receptor beta | / | 0.443 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.443 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.443 | |
| 1wbp | ADP | SRSF protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.443 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.443 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.443 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.443 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.443 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4kio | G5K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 5hy5 | FAD | Tryptophan 6-halogenase | / | 0.443 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.442 | |
| 1r2j | FAD | FkbI | / | 0.442 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.442 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.442 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.442 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.442 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.442 | |
| 2pxa | SAH | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3v49 | PK0 | Androgen receptor | / | 0.442 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.442 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.441 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.441 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.441 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2wa2 | SAM | Genome polyprotein | / | 0.441 | |
| 2wbd | RO5 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.441 | |
| 3arv | SAU | Chitinase A | / | 0.441 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.441 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.441 | |
| 4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.441 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.441 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.441 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.441 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1iky | MSD | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1tv8 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.440 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3aba | FLI | Cytochrome P450 | / | 0.440 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.440 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.440 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4lb2 | DM5 | Serum albumin | / | 0.440 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.440 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.440 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.440 |