scPDB - Distribution of Binding site Similarity values of 1efl entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1efl	NAD	NAD-dependent malic enzyme, mitochondrial	1.1.1.38

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1efl	NAD	NAD-dependent malic enzyme, mitochondrial	1.1.1.38	1.000
1pj2	NAI	NAD-dependent malic enzyme, mitochondrial	1.1.1.38	0.713
1pj3	NAD	NAD-dependent malic enzyme, mitochondrial	1.1.1.38	0.697
1efk	NAD	NAD-dependent malic enzyme, mitochondrial	1.1.1.38	0.670
1do8	NAD	NAD-dependent malic enzyme, mitochondrial	1.1.1.38	0.589
1gz4	ATP	NAD-dependent malic enzyme, mitochondrial	1.1.1.38	0.527
1gq2	NAP	NADP-dependent malic enzyme	1.1.1.40	0.501