Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1eag | A70 | Candidapepsin-2 | 3.4.23.24 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1eag | A70 | Candidapepsin-2 | 3.4.23.24 | 1.000 | |
| 1zap | A70 | Candidapepsin-2 | 3.4.23.24 | 0.611 | |
| 3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.607 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.555 | |
| 1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.484 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.469 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.461 | |
| 1gvt | 2ZS | Endothiapepsin | 3.4.23.22 | 0.460 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.460 | |
| 1gvw | 0EM | Endothiapepsin | 3.4.23.22 | 0.459 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.442 |