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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1eagA70Candidapepsin-23.4.23.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1eagA70Candidapepsin-23.4.23.241.000
1zapA70Candidapepsin-23.4.23.240.611
3q70RITCandidapepsin-23.4.23.240.607
3tneRITCandidapepsin-13.4.23.240.555
1od10QSEndothiapepsin3.4.23.220.484
3t7x4SHEndothiapepsin3.4.23.220.469
3prsRITEndothiapepsin3.4.23.220.461
1gvt2ZSEndothiapepsin3.4.23.220.460
3pwwROCEndothiapepsin3.4.23.220.460
1gvw0EMEndothiapepsin3.4.23.220.459
1e81M91Endothiapepsin3.4.23.220.442