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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1e62FADFerredoxin--NADP reductase1.18.1.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1e62FADFerredoxin--NADP reductase1.18.1.21.000
1h42FADFerredoxin--NADP reductase1.18.1.20.834
1ogiFADFerredoxin--NADP reductase1.18.1.20.789
1gr1FADFerredoxin--NADP reductase1.18.1.20.737
1ogjFADFerredoxin--NADP reductase1.18.1.20.725
1queFADFerredoxin--NADP reductase1.18.1.20.693
1bjkFADFerredoxin--NADP reductase1.18.1.20.679
1e64FADFerredoxin--NADP reductase1.18.1.20.676
4c43FADFerredoxin--NADP reductase1.18.1.20.653
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.651
1e63FADFerredoxin--NADP reductase1.18.1.20.643
1w35FADFerredoxin--NADP reductase1.18.1.20.640
3zbtFADFerredoxin--NADP reductase1.18.1.20.632
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.630
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.630
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.618
1gawFADFerredoxin/0.614
1qgyFADFerredoxin--NADP reductase1.18.1.20.611
1gjrFADFerredoxin--NADP reductase1.18.1.20.610
3zc3FADFerredoxin--NADP reductase1.18.1.20.607
1qgzFADFerredoxin--NADP reductase1.18.1.20.603
2b5oFADFerredoxin--NADP reductase1.18.1.20.603
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.598
1qh0FADFerredoxin--NADP reductase1.18.1.20.596
1sm4FADFerredoxin--NADP reductase/0.596
3vo2FADFerredoxin--NADP reductase/0.595
1gaqFADFerredoxin/0.594
4bprFADFerredoxin--NADP reductase1.18.1.20.594
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.590
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.589
1h85FADFerredoxin--NADP reductase1.18.1.20.587
1go2FADFerredoxin--NADP reductase1.18.1.20.580
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.579
2rc6FADFerredoxin--NADP reductase/0.570
3w5uFADFerredoxin/0.553
1ewyFADFerredoxin--NADP reductase1.18.1.20.552
1w87FADFerredoxin--NADP reductase1.18.1.20.538
3fpkFADFerredoxin-NADP reductase/0.538
3qe2FADNADPH--cytochrome P450 reductase/0.535
3qfcFADNADPH--cytochrome P450 reductase/0.533
3jqrFADFerredoxin--NADP reductase, apicoplast/0.530
1b2rFADFerredoxin--NADP reductase1.18.1.20.527
1ja1FADNADPH--cytochrome P450 reductase/0.526
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.510
1x1bSAHC-20 methyltransferase/0.509
1gky5GPGuanylate kinase2.7.4.80.507
2ok8FADFerredoxin--NADP reductase, apicoplast/0.507
4b4vL34Bifunctional protein FolD/0.507
4b4w9L9Bifunctional protein FolD/0.506
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.505
5a4vQUEGlutathione S-transferase F22.5.1.180.505
2piaFMNPhthalate dioxygenase reductase/0.502
3qftFADNADPH--cytochrome P450 reductase/0.502
3qfsFADNADPH--cytochrome P450 reductase/0.498
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.498
1j9zFADNADPH--cytochrome P450 reductase/0.497
3busSAHDemethylrebeccamycin-D-glucose O-methyltransferase/0.497
1ex75GPGuanylate kinase2.7.4.80.493
2rc5FADFerredoxin--NADP reductase/0.492
4yaoFADNADPH--cytochrome P450 reductase/0.492
2bpoFADNADPH--cytochrome P450 reductase/0.491
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.491
4y7cFADNADPH--cytochrome P450 reductase/0.490
1pqc444Oxysterols receptor LXR-beta/0.489
1x1cSAHC-20 methyltransferase/0.488
1vbiNADMalate/L-lactate dehydrogenase family protein/0.487
1x1dSAHC-20 methyltransferase/0.486
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.486
4bfxZVXPantothenate kinase2.7.1.330.486
3kp4MIITranscriptional regulator TcaR/0.485
4y9uFADNADPH--cytochrome P450 reductase/0.485
2jf6S55Strictosidine-O-beta-D-glucosidase3.2.1.1050.484
2ejzSAHDiphthine synthase/0.483
4yafFADNADPH--cytochrome P450 reductase/0.483
2bf4FADNADPH--cytochrome P450 reductase/0.482
3ske054Genome polyprotein2.7.7.480.482
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.482
4bfuZVUPantothenate kinase2.7.1.330.481
4yauFADNADPH--cytochrome P450 reductase/0.481
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.480
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.480
4bftZVTPantothenate kinase2.7.1.330.480
2ptfFMNUncharacterized protein MTH_863/0.478
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.478
4bfvZVVPantothenate kinase2.7.1.330.478
4y9rFADNADPH--cytochrome P450 reductase/0.478
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.477
1w34FADFerredoxin--NADP reductase1.18.1.20.477
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.477
2hxzH7JCathepsin S3.4.22.270.476
2jb4A14Isopenicillin N synthase1.21.3.10.476
1hb1OCVIsopenicillin N synthase1.21.3.10.475
2iviACWIsopenicillin N synthase1.21.3.10.475
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.475
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.475
1diaL24C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.474
1hb3SCVIsopenicillin N synthase1.21.3.10.474
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.474
4b2gV1NUncharacterized protein/0.474
4rkdKETAminotransferase/0.474
1r5hAO2Methionine aminopeptidase 2/0.473
3p2oNADBifunctional protein FolD/0.473
5irnADPNucleotide binding oligomerization domain containing 2/0.473
1h60STRPentaerythritol tetranitrate reductase/0.472
3vf60H6Glucokinase2.7.1.20.472
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.472
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.471
2g8yNADHydroxycarboxylate dehydrogenase B/0.471
4b7754MBeta-secretase 13.4.23.460.471
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.471
1amoFADNADPH--cytochrome P450 reductase/0.470
4n4wSNTSmoothened homolog/0.470
1pq944BOxysterols receptor LXR-beta/0.469
2zevIPEGeranylgeranyl pyrophosphate synthase/0.469
3rtnRTNBeta-secretase 13.4.23.460.469
4wx2F6FTryptophan synthase alpha chain/0.469
4wx2F6FTryptophan synthase beta chain4.2.1.200.469
2x06NADL-sulfolactate dehydrogenase/0.468
2gciMRRProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.467
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.467
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.466
2vn1FK5Peptidylprolyl isomerase/0.466
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.466
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.466
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.466
3nt5NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.466
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.466
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.466
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.465
3c1oNAPEugenol synthase/0.465
3sf6FDAGlutaryl-CoA dehydrogenase/0.465
4bb3KKAIsopenicillin N synthase1.21.3.10.465
4kbyC2EStimulator of interferon genes protein/0.465
1tllFADNitric oxide synthase, brain1.14.13.390.464
1vceSAHDiphthine synthase/0.464
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.464
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.464
3i0pNADMalate dehydrogenase, putative/0.464
4j7hTRHPCZA361.3/0.464
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.463
2zevB71Geranylgeranyl pyrophosphate synthase/0.463
3zkyWT4Isopenicillin N synthase1.21.3.10.463
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4wctFADFructosyl amine:oxygen oxidoreductase/0.463
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.462
4a87NARMajor pollen allergen Bet v 1-A/0.462
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.462
1ndzFR5Adenosine deaminase3.5.4.40.461
2dsgSAHDiphthine synthase/0.461
2y01Y00Beta-1 adrenergic receptor/0.461
3e78TPPHigh affinity transport system protein p37/0.461
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.461
4b67FADL-ornithine N(5)-monooxygenase/0.461
4j171HQBeta-secretase 13.4.23.460.461
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.461
1kceCB3Thymidylate synthase/0.460
1qcjAPTAntiviral protein I3.2.2.220.460
2ct8MSPMethionine--tRNA ligase6.1.1.100.460
2r6hFADNa(+)-translocating NADH-quinone reductase subunit F/0.460
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.460
3e6eDCSAlanine racemase/0.460
3tzaTZGGlutamate receptor 2/0.460
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.459
1qzyTDEMethionine aminopeptidase 2/0.459
3anmSYD1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.459
3gynB42Genome polyprotein2.7.7.480.459
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.459
3wleNAD(R)-specific carbonyl reductase/0.459
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.459
4x9dU5PUncharacterized protein MJ1435/0.459
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.458
1qtqQSIGlutamine--tRNA ligase6.1.1.180.458
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.458
2wjoQUDBeta-secretase 13.4.23.460.458
2ztsADPUncharacterized protein/0.458
3gncQQQGlutaryl-CoA dehydrogenase/0.458
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.458
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.458
1pkfEPDEpothilone C/D epoxidase1.140.457
2bf4FMNNADPH--cytochrome P450 reductase/0.457
2vkeTACTetracycline repressor protein class D/0.457
3iktNADRedox-sensing transcriptional repressor Rex/0.457
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.457
3q44D50M1 family aminopeptidase3.4.110.457
3uayADNPurine nucleoside phosphorylase DeoD-type/0.457
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.457
5a4wQCTGlutathione S-transferase F22.5.1.180.457
5ah5LSSLeucine--tRNA ligase/0.457
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.456
1n3sGTPGTP cyclohydrolase 13.5.4.160.456
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.456
2ejkSAHDiphthine synthase/0.456
2w02ATPAcsD/0.456
3bnkFMNFlavoredoxin/0.456
3ojwFMNNADPH--cytochrome P450 reductase/0.456
3t37FADPyridoxine 4-oxidase/0.456
3zpqXF5Beta-1 adrenergic receptor/0.456
1qiqACCIsopenicillin N synthase1.21.3.10.455
2ea2F77Methionine aminopeptidase 2/0.455
2emuSAHDiphthine synthase/0.455
2gevCOKPantothenate kinase2.7.1.330.455
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.455
3ojwFADNADPH--cytochrome P450 reductase/0.455
1akaPLPAspartate aminotransferase, mitochondrial2.6.1.10.454
1kzuRG1Light-harvesting protein B-800/850 alpha chain/0.454
1kzuRG1Light-harvesting protein B-800/850 beta chain/0.454
2geuCOKPantothenate kinase2.7.1.330.454
2lfoGCHFatty acid-binding protein, liver/0.454
2p6dSAHDiphthine synthase/0.454
2pb6SAHDiphthine synthase/0.454
3ojxFADNADPH--cytochrome P450 reductase/0.454
3ox279XRibosyldihydronicotinamide dehydrogenase [quinone]/0.454
4ac0MIYTetracycline repressor protein class B from transposon Tn10/0.454
4bvnP32Beta-1 adrenergic receptor/0.454
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.454
1lb9DNQGlutamate receptor 2/0.453
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.453
2e16SAHDiphthine synthase/0.453
3b7dCNIGlutamate receptor 2/0.453
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.453
3l77NJPShort-chain alcohol dehydrogenase/0.453
4az3S35Lysosomal protective protein3.4.16.50.453
4da8BG2Purine nucleoside phosphorylase DeoD-type2.4.2.10.453
4phlPILPhosphodiesterase/0.453
4xbfFADLysine-specific histone demethylase 1A10.453
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1xddAAYIntegrin alpha-L/0.452
1ypeUIPProthrombin3.4.21.50.452
2npfMOUElongation factor 2/0.452
2yac937Serine/threonine-protein kinase PLK12.7.11.210.452
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.452
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.452
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.452
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.452
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.452
4ea2RWZDehydrosqualene synthase/0.452
4nzhFADL-ornithine N(5)-monooxygenase/0.452
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.451
1fdrFADFerredoxin--NADP reductase1.18.1.20.451
1h61PDNPentaerythritol tetranitrate reductase/0.451
1pr4MTPPurine nucleoside phosphorylase DeoD-type/0.451
1s9dAFBCytohesin-2/0.451
1s9dAFBADP-ribosylation factor 1/0.451
1thnADPAnti-sigma F factor/0.451
1x1aSAMC-20 methyltransferase/0.451
1yw8A75Methionine aminopeptidase 2/0.451
2an9GDPGuanylate kinase2.7.4.80.451
2eh5SAHDiphthine synthase/0.451
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.451
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.451
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3otwCOAPhosphopantetheine adenylyltransferase/0.451
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.451
4d9eLCSD-cysteine desulfhydrase/0.451
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4jlj1NMDeoxycytidine kinase2.7.1.740.451
4mlp2CXCryptochrome-2/0.451
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.451
1mrqSTRAldo-keto reductase family 1 member C1/0.450
2bf7HBIPteridine reductase 11.5.1.330.450
2ed3SAHDiphthine synthase/0.450
2re8GSUGlutamine--tRNA ligase6.1.1.180.450
3ekuCY9Actin-5C/0.450
3rviRVIBeta-secretase 13.4.23.460.450
3tyvHI3Genome polyprotein2.7.7.480.450
3ufl508Beta-secretase 13.4.23.460.450
4b63FADL-ornithine N(5)-monooxygenase/0.450
4bfwZVWPantothenate kinase2.7.1.330.450
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.450
5dozNDPJamJ/0.450
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
1r8qAFBCytohesin-2/0.449
1r8qAFBADP-ribosylation factor 1/0.449
1tilATPAnti-sigma F factor/0.449
1xs7MMIBeta-secretase 13.4.23.460.449
2ay95PVAromatic-amino-acid aminotransferase2.6.1.570.449
2bu9HFVIsopenicillin N synthase1.21.3.10.449
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.449
2cb3MLDPeptidoglycan-recognition protein LE/0.449
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.449
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.449
3h3sH15Collagen type IV alpha-3-binding protein/0.449
4e32DWNMethyltransferase/0.449
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.449
4qohSTLRibosyldihydronicotinamide dehydrogenase [quinone]/0.449
4rrrA3TThreonine--tRNA ligase6.1.1.30.449
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.448
1cqxFADFlavohemoprotein/0.448
1h51FMNPentaerythritol tetranitrate reductase/0.448
1jqdSAHHistamine N-methyltransferase2.1.1.80.448
2clfF6FTryptophan synthase alpha chain/0.448
2po3T4K4-dehydrase/0.448
2vbdV10Isopenicillin N synthase1.21.3.10.448
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.448
3br3ETHTH-type transcriptional regulator QacR/0.448
3dbuD8WCarbonic anhydrase 24.2.1.10.448
3dv5BAVBeta-secretase 13.4.23.460.448
3nhpHGZRibosyldihydronicotinamide dehydrogenase [quinone]/0.448
4fkzUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.448
4tm1FDAKtzI/0.448
5d6lCAUBeta-2 adrenergic receptor/0.448
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.447
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
2g247IGRenin3.4.23.150.447
3aho3A2Oligopeptidase/0.447
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.447
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
4bekXK0Beta-secretase 13.4.23.460.447
4jq4IMNAldo-keto reductase family 1 member C2/0.447
5f54TMPSingle-stranded-DNA-specific exonuclease/0.447
1dgfNDPCatalase1.11.1.60.446
1o2g696Prothrombin3.4.21.50.446
1yunATPProbable nicotinate-nucleotide adenylyltransferase2.7.7.180.446
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.446
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2cleF6FTryptophan synthase alpha chain/0.446
2ek7SAHDiphthine synthase/0.446
2jl1NAPTriphenylmethane reductase/0.446
2nr4FMNConserved protein/0.446
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.446
3nhjA2ZRibosyldihydronicotinamide dehydrogenase [quinone]/0.446
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.446
3ojxFMNNADPH--cytochrome P450 reductase/0.446
3owxXRARibosyldihydronicotinamide dehydrogenase [quinone]/0.446
3rsv3RSBeta-secretase 13.4.23.460.446
4amjCVDBeta-1 adrenergic receptor/0.446
4mka2AYGenome polyprotein2.7.7.480.446
4oztP1AEcdysone receptor, putative/0.446
4rquNADAlcohol dehydrogenase class-P/0.446
5fx2FMNFlavodoxin/0.446
5h86BCOHistone acetyltransferase KAT2A2.3.1.480.446
1cm0COAHistone acetyltransferase KAT2B2.3.1.480.445
1f20FADNitric oxide synthase, brain1.14.13.390.445
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.445
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.445
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.445
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.445
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.445
1w6jR71Lanosterol synthase5.4.99.70.445
2aclL05Oxysterols receptor LXR-alpha/0.445
2e0nSAHPrecorrin-2 C20-methyltransferase/0.445
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.445
2y60M8FIsopenicillin N synthase1.21.3.10.445
2y6fM9FIsopenicillin N synthase1.21.3.10.445
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.445
3oadLPORenin3.4.23.150.445
4bfzZVZPantothenate kinase2.7.1.330.445
4c717RD3-oxoacyl-ACP synthase/0.445
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.445
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.445
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.445
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.445
5dp2NAPCurF/0.445
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.444
1s4oGDPGlycolipid 2-alpha-mannosyltransferase/0.444
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.444
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1z4rACOHistone acetyltransferase KAT2A2.3.1.480.444
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
2e94364Geranylgeranyl pyrophosphate synthase/0.444
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.444
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3csoXNIGenome polyprotein2.7.7.480.444
3dd0EZLCarbonic anhydrase 24.2.1.10.444
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3n71SFGHistone-lysine N-methyltransferase Smyd1/0.444
3p0fBAUUridine phosphorylase 22.4.2.30.444
3qfrFMNNADPH--cytochrome P450 reductase/0.444
3zc3NAPFerredoxin--NADP reductase1.18.1.20.444
4jt91NSNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.444
4l7h1W1Beta-secretase 13.4.23.460.444
1a8pFADFerredoxin--NADP reductase/0.443
1e79ATPATP synthase subunit alpha, mitochondrial/0.443
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.443
1r58AO5Methionine aminopeptidase 2/0.443
1xf0ASDAldo-keto reductase family 1 member C3/0.443
2ehlSAHDiphthine synthase/0.443
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.443
2owvSAHDiphthine synthase/0.443
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.443
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.443
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3ivcFG4Pantothenate synthetase6.3.2.10.443
3mj4URMUDP-galactopyranose mutase/0.443
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.443
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.443
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.443
4k38SAMAnaerobic sulfatase-maturating enzyme1.8.980.443
4obwSAM2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial/0.443
4rxpDTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
4tlaADPCircadian clock protein kinase KaiC2.7.11.10.443
4to5DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
1d3dBZTProthrombin3.4.21.50.442
1fmlRTLRetinol dehydratase/0.442
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.442
1umlFR4Adenosine deaminase3.5.4.40.442
1wl4COAAcetyl-CoA acetyltransferase, cytosolic2.3.1.90.442
1x8lOXRRetinol dehydratase/0.442
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.442
3dwbRDFEndothelin-converting enzyme 13.4.24.710.442
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3ei8PL5LL-diaminopimelate aminotransferase, chloroplastic/0.442
3oqfS51Renin3.4.23.150.442
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
3pm1ETHTH-type transcriptional regulator QacR/0.442
3q43D66M1 family aminopeptidase3.4.110.442
4ba5PXGProbable aminotransferase/0.442
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.442
4mm729JNa(+):neurotransmitter symporter (Snf family)/0.442
5d5bCAUBeta-2 adrenergic receptor/0.442
1hrvSDZGenome polyprotein/0.441
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2giqNN2Genome polyprotein2.7.7.480.441
2vcmM11Isopenicillin N synthase1.21.3.10.441
2vprTDCTetracycline repressor protein class H/0.441
2vqjTFGHistone deacetylase 43.5.1.980.441
2vt4P32Beta-1 adrenergic receptor/0.441
2ydoADNAdenosine receptor A2a/0.441
2zbzVDXVitamin D3 dihydroxylase/0.441
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.441
3bsc2PDGenome polyprotein2.7.7.480.441
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.441
3da24MDCarbonic anhydrase 134.2.1.10.441
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3eksCY9Actin-5C/0.441
3frkTQPQdtB/0.441
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.441
3s5wFADL-ornithine N(5)-monooxygenase/0.441
3v0n4GWHisto-blood group ABO system transferase/0.441
4b65FADL-ornithine N(5)-monooxygenase/0.441
4cdmFO1Deoxyribodipyrimidine photolyase/0.441
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.441
4k1xFADNADPH:ferredoxin reductase/0.441
4nmkNAPAldehyde dehydrogenase/0.441
1ejeFMNProtein MTH_152/0.440
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.440
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1fduNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.440
1o5gCR9Prothrombin3.4.21.50.440
1odjGMPPurine nucleoside phosphorylase/0.440
1sqi8694-hydroxyphenylpyruvate dioxygenase/0.440
1uzwCDHIsopenicillin N synthase1.21.3.10.440
1ypjUIBProthrombin3.4.21.50.440
2cndFADNitrate reductase [NADH]1.7.1.10.440
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.440
3bt9DEQHTH-type transcriptional regulator QacR/0.440
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.440
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.440
3fhxPXLPyridoxal kinase2.7.1.350.440
3h0bB35Beta-secretase 13.4.23.460.440
3h2sNDPPutative NADH-flavin reductase/0.440
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.440
4bfyZVYPantothenate kinase2.7.1.330.440
4dz7D02Carbonic anhydrase 24.2.1.10.440
4isuIKMGlutamate receptor 2/0.440
4j0t6T9Beta-secretase 13.4.23.460.440
4j0v1H7Beta-secretase 13.4.23.460.440
4wasCOOEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.440
4u140HKMuscarinic acetylcholine receptor M3/0.440
4u163C0Muscarinic acetylcholine receptor M3/0.440