sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1e2j | THM | Thymidine kinase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1e2j | THM | Thymidine kinase | / | 1.000 | |
| 1e2n | RCA | Thymidine kinase | / | 0.559 | |
| 4ivq | I43 | Thymidine kinase | / | 0.549 | |
| 4ivr | N50 | Thymidine kinase | / | 0.537 | |
| 4jbx | SK7 | Thymidine kinase | / | 0.492 | |
| 1e2l | TMC | Thymidine kinase | / | 0.491 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.488 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.486 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.485 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.484 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.479 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.477 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.476 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.474 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.474 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.471 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.467 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.465 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.462 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.455 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.453 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.451 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.450 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
| 2vqs | BVD | Deoxynucleoside kinase | / | 0.447 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.446 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.446 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 1zdw | FLV | Prenyltransferase | / | 0.444 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.443 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.442 |