Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1e1v | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1e1v | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 1.000 | |
| 3r73 | X87 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.668 | |
| 3r71 | X86 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.625 | |
| 3qx4 | X4B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.616 | |
| 2r3g | SC9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.607 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.592 | |
| 3rpo | 24Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.585 | |
| 3qqf | X07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.584 | |
| 3r7y | Z04 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.583 | |
| 2c6m | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.581 | |
| 1h0w | 207 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.579 | |
| 3qwj | X6A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.575 | |
| 1e1x | NW1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.574 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.569 | |
| 3r8v | Z62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.569 | |
| 1h1q | 2A6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.567 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.563 | |
| 1pxk | CK3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.562 | |
| 1h1p | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.561 | |
| 1b39 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.558 | |
| 3r6x | X84 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.558 | |
| 3fz1 | B98 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.557 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.557 | |
| 2r3o | 2SC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.555 | |
| 1vyz | N5B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.553 | |
| 3qql | X03 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.552 | |
| 3qx2 | X63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.551 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.551 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.550 | |
| 2r3i | SCF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.549 | |
| 2r3r | 6SC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.549 | |
| 3r8u | Z31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.549 | |
| 1h0v | UN4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.548 | |
| 1w8c | N69 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.548 | |
| 4eol | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.547 | |
| 3qzi | X72 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.540 | |
| 2r64 | 740 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.539 | |
| 3r1y | X76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.539 | |
| 3qru | X19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.537 | |
| 4eos | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.536 | |
| 3ql8 | X01 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.535 | |
| 3s0o | 50Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.534 | |
| 1b38 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.532 | |
| 1ykr | 628 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.531 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.531 | |
| 3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.530 | |
| 3r7v | Z02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.530 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.529 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.528 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.528 | |
| 2c6o | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.527 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.525 | |
| 3roy | 22Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.523 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.523 | |
| 1gz8 | MBP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.522 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.521 | |
| 3igg | EFQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.519 | |
| 3r7u | X96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.519 | |
| 3sqq | 99Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.519 | |
| 4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.517 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.516 | |
| 4kd1 | 1QK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.516 | |
| 3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.514 | |
| 3r8p | Z46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.514 | |
| 4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.514 | |
| 1v1k | 3FP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.512 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.512 | |
| 4lyn | 1YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.512 | |
| 3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.511 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.509 | |
| 2fvd | LIA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.509 | |
| 3qtr | X36 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.509 | |
| 3qzf | X66 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.509 | |
| 3s00 | Z60 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.509 | |
| 2a0c | CK9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.507 | |
| 1oit | HDT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.506 | |
| 2a4l | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.506 | |
| 3r1q | X75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.506 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.506 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.506 | |
| 4eop | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.505 | |
| 2vtp | LZ9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.503 | |
| 3ti1 | B49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.503 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.503 | |
| 2r3f | SC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 3lfs | A07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 3qqh | X0A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 3rkb | 12Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 4fkt | 48K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 1dm2 | HMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.501 | |
| 1r78 | FMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.500 | |
| 3rah | O1Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.500 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.499 | |
| 1ke5 | LS1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.498 | |
| 1gy3 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.497 | |
| 2r3p | 3SC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.497 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.496 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 3qtx | X43 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.494 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
| 2c5y | MTW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
| 3rpr | 25Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
| 3qzh | X69 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.492 | |
| 4bgh | 3I6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.492 | |
| 2c6k | DT2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 2b54 | D05 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.490 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.489 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.489 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.488 | |
| 2c6i | DT1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.488 | |
| 3r28 | XA0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 3r9n | Z68 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 1ke7 | LS3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 1w0x | OLO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 2c68 | CT6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 1pxm | CK5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 4fkq | 42K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 3r8l | Z30 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.482 | |
| 3wbl | PDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.482 | |
| 1pxp | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 2btr | U73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.479 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.478 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 3qrt | X14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 3rjc | 06Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.474 | |
| 4fv4 | EK7 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.474 | |
| 1jst | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 1y91 | CT9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 2c4g | 514 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 2c6l | DT4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.472 | |
| 1oiq | HDU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 2vtl | LZ5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 5ani | ES4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.469 | |
| 4ivd | 15T | Tyrosine-protein kinase JAK1 | / | 0.469 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 2j9m | PY8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.468 | |
| 3qxp | X64 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 1pxo | CK7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.467 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.467 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.465 | |
| 4fks | 46K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 3sw4 | 18K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 2uzo | C62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 2w1h | L0F | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4fv8 | E63 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.462 | |
| 1urw | I1P | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3v3v | MYU | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.461 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.461 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.461 | |
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.461 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.460 | |
| 2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.460 | |
| 3qyw | 6PB | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.460 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2r3j | SCJ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.459 | |
| 1sdt | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.458 | |
| 3b89 | 5GP | 16S rRNA methylase | / | 0.458 | |
| 3niz | ADP | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.458 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
| 3qtq | X35 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.458 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.457 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.457 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.456 | |
| 2r3q | 5SC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.456 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.456 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.455 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2vts | LZC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2xnb | Y8L | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4au8 | Z3R | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.454 | |
| 5cyq | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 1y8y | CT7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2xmy | CDK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.453 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.453 | |
| 2vth | LZ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 3qqg | X06 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3r1s | X73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3t99 | ADP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.452 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.452 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.452 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3nxe | 2NC | Protease | / | 0.451 | |
| 3qts | X46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3tnw | F18 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 5dp2 | NAP | CurF | / | 0.451 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.450 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.450 | |
| 1sdu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4nj3 | 2KD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.450 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1hck | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2pvk | P45 | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 3uo5 | 0BX | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 4ivb | 1J5 | Tyrosine-protein kinase JAK1 | / | 0.448 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.447 | |
| 3liv | E16 | Protease | / | 0.447 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.447 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.447 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4j55 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1hwr | 216 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1pxj | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 2bpy | 3IN | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2xng | A0H | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.445 | |
| 1c70 | L75 | Protease | / | 0.444 | |
| 1d4h | BEH | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.444 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1ol7 | ADP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 1pye | PM1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.444 | |
| 2r3l | SCW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.444 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.443 | |
| 1daz | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2a4f | AAU | V-1 protease | / | 0.443 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.443 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.443 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3d1y | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.443 | |
| 1c6y | MK1 | Protease | / | 0.442 | |
| 1fff | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1izi | Q50 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.442 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.442 | |
| 2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3gga | GGW | Gag-Pol polyprotein | / | 0.442 | |
| 3uim | ANP | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | 2.7.10.1 | 0.442 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.442 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.442 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.442 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.441 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.441 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.441 | |
| 2hc0 | AB2 | Protease | / | 0.441 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.441 | |
| 2q63 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.441 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.441 | |
| 3unj | 0BX | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.441 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 1bv7 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1sx4 | ADP | 60 kDa chaperonin | / | 0.440 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.440 | |
| 1zao | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.440 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.440 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 3cr3 | ADP | PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.440 | |
| 3ekx | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.440 | |
| 3okx | SAM | S-adenosyl-L-methionine-binding protein RPA0152 | / | 0.440 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4dqb | 017 | Gag-Pol polyprotein | / | 0.440 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.440 |