scPDB - Distribution of Binding site Similarity values of 1dyj entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1dyj	DDF	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	1.000
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.745
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.727
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.712
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.705
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.669
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.611
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.606
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.599
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.595
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.575
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.574
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.569
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.568
5hi6	MTX	Dihydrofolate reductase	/	0.567
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.556
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.542
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.541
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.532
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.530
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.517
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.507
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.506
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.494
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.489
4elb	34S	Dihydrofolate reductase	/	0.475
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.465
2qk8	MTX	Dihydrofolate reductase	/	0.465
4i1n	FOL	Dihydrofolate reductase	1.5.1.3	0.465
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.464
4elg	52J	Dihydrofolate reductase	/	0.457
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.454
4ele	31I	Dihydrofolate reductase	/	0.454
5ccc	DDF	Dihydrofolate reductase	1.5.1.3	0.454
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.453
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.452
3fl8	RAR	Dihydrofolate reductase	/	0.452
4x5g	FOL	Dihydrofolate reductase	1.5.1.3	0.447
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.446
1ra3	MTX	Dihydrofolate reductase	1.5.1.3	0.443
2ejv	NAD	L-threonine 3-dehydrogenase	/	0.442
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.441