scPDB - Distribution of Binding site Similarity values of 1drb entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1drb	MTX	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1drb	MTX	Dihydrofolate reductase	1.5.1.3	1.000
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.712
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.634
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.617
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.612
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.602
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.601
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.599
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.574
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.571
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.566
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.563
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.548
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.545
5hi6	MTX	Dihydrofolate reductase	/	0.532
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.511
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.497
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.492
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.471
4ele	31I	Dihydrofolate reductase	/	0.471
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.459
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.453
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.443
4elb	34S	Dihydrofolate reductase	/	0.443
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.442
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.441