sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 1.000 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.647 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.627 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.597 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.592 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.588 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.587 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.586 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.569 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.567 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.561 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.558 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.553 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.511 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.504 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 3cse | N22 | Uncharacterized protein | / | 0.496 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.492 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.490 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.484 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 4p68 | MTX | Dihydrofolate reductase | / | 0.482 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 3eej | 53R | Uncharacterized protein | / | 0.481 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.480 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.473 | |
| 3eem | 53V | Uncharacterized protein | / | 0.472 | |
| 5dp2 | NAP | CurF | / | 0.470 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.469 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.469 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.468 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.468 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.467 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.466 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.466 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.465 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.465 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.463 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.463 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.463 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.462 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.461 | |
| 3qly | 55V | Uncharacterized protein | / | 0.460 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.460 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.460 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.459 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.458 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.456 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.455 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.455 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.455 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.455 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.455 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.453 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.453 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.453 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.452 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.452 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 1zdw | FLV | Prenyltransferase | / | 0.452 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.452 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.452 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.452 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.451 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.451 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.450 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.449 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4iah | 1DX | Alr2278 protein | / | 0.449 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.448 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.448 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.448 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.447 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.447 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.447 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.447 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.446 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.446 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.446 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.446 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.445 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.445 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.445 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.445 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.445 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.445 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.444 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.444 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.442 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.442 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3arv | SAU | Chitinase A | / | 0.442 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2ejz | SAH | Diphthine synthase | / | 0.441 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.441 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.441 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4bwa | N0B | Pyrrolysine--tRNA ligase | / | 0.441 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4z9r | NAD | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.441 | |
| 1syn | F89 | Thymidylate synthase | / | 0.440 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.440 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.440 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.440 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.440 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3eek | 53S | Uncharacterized protein | / | 0.440 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.440 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.440 |