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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1dm2HMDCyclin-dependent kinase 22.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1dm2HMDCyclin-dependent kinase 22.7.11.221.000
2c6tDT5Cyclin-dependent kinase 22.7.11.220.630
3r9hZ67Cyclin-dependent kinase 22.7.11.220.618
3ti1B49Cyclin-dependent kinase 22.7.11.220.616
4fkr45KCyclin-dependent kinase 22.7.11.220.611
4fkv61KCyclin-dependent kinase 22.7.11.220.611
3ral04ZCyclin-dependent kinase 22.7.11.220.605
1w0xOLOCyclin-dependent kinase 22.7.11.220.603
1y91CT9Cyclin-dependent kinase 22.7.11.220.601
3rmf20ZCyclin-dependent kinase 22.7.11.220.601
1fvv107Cyclin-dependent kinase 22.7.11.220.600
2uzlC94Cyclin-dependent kinase 22.7.11.220.598
1p2a5BNCyclin-dependent kinase 22.7.11.220.595
2r64740Cyclin-dependent kinase 22.7.11.220.594
3s2pPMUCyclin-dependent kinase 22.7.11.220.594
3rak03ZCyclin-dependent kinase 22.7.11.220.593
3qtxX43Cyclin-dependent kinase 22.7.11.220.591
3rpv26ZCyclin-dependent kinase 22.7.11.220.591
1gih1PUCyclin-dependent kinase 22.7.11.220.590
3rni21ZCyclin-dependent kinase 22.7.11.220.589
3rk708ZCyclin-dependent kinase 22.7.11.220.586
2bhhRYUCyclin-dependent kinase 22.7.11.220.585
3qxpX64Cyclin-dependent kinase 22.7.11.220.584
3rk909ZCyclin-dependent kinase 22.7.11.220.584
3qtzX42Cyclin-dependent kinase 22.7.11.220.583
3s1h56ZCyclin-dependent kinase 22.7.11.220.583
4eok4SPCyclin-dependent kinase 22.7.11.220.581
3qqkX02Cyclin-dependent kinase 22.7.11.220.580
3rk507ZCyclin-dependent kinase 22.7.11.220.580
4ek816KCyclin-dependent kinase 22.7.11.220.579
3r9dX6BCyclin-dependent kinase 22.7.11.220.575
2xmyCDKCyclin-dependent kinase 22.7.11.220.574
4erwSTUCyclin-dependent kinase 22.7.11.220.574
2uznC96Cyclin-dependent kinase 22.7.11.220.573
1ckpPVBCyclin-dependent kinase 22.7.11.220.572
2duv371Cyclin-dependent kinase 22.7.11.220.572
3uli1N3Cyclin-dependent kinase 22.7.11.220.572
2x1nX1NCyclin-dependent kinase 22.7.11.220.569
1pkdUCNCyclin-dependent kinase 22.7.11.220.568
1pyePM1Cyclin-dependent kinase 22.7.11.220.568
2btsU32Cyclin-dependent kinase 22.7.11.220.567
2uzdC85Cyclin-dependent kinase 22.7.11.220.565
3lfsA07Cyclin-dependent kinase 22.7.11.220.564
1oirHDYCyclin-dependent kinase 22.7.11.220.563
2wihP48Cyclin-dependent kinase 22.7.11.220.563
4fx360KCyclin-dependent kinase 22.7.11.220.562
2r3lSCWCyclin-dependent kinase 22.7.11.220.561
1fvt106Cyclin-dependent kinase 22.7.11.220.560
3qu0X40Cyclin-dependent kinase 22.7.11.220.560
2bheBRYCyclin-dependent kinase 22.7.11.220.558
3qtqX35Cyclin-dependent kinase 22.7.11.220.558
3qxoX65Cyclin-dependent kinase 22.7.11.220.558
4fks46KCyclin-dependent kinase 22.7.11.220.558
4fkw62KCyclin-dependent kinase 22.7.11.220.558
2c5nCK8Cyclin-dependent kinase 22.7.11.220.557
2iw84SPCyclin-dependent kinase 22.7.11.220.557
2w17I19Cyclin-dependent kinase 22.7.11.220.557
2i40BLZCyclin-dependent kinase 22.7.11.220.556
2r3p3SCCyclin-dependent kinase 22.7.11.220.556
3rkb12ZCyclin-dependent kinase 22.7.11.220.556
2uzeC95Cyclin-dependent kinase 22.7.11.220.555
2wpa889Cyclin-dependent kinase 22.7.11.220.555
3roy22ZCyclin-dependent kinase 22.7.11.220.555
1ke9LS5Cyclin-dependent kinase 22.7.11.220.554
3qqfX07Cyclin-dependent kinase 22.7.11.220.554
1oitHDTCyclin-dependent kinase 22.7.11.220.553
3qzfX66Cyclin-dependent kinase 22.7.11.220.553
3s0o50ZCyclin-dependent kinase 22.7.11.220.552
1v1k3FPCyclin-dependent kinase 22.7.11.220.551
3r1qX75Cyclin-dependent kinase 22.7.11.220.551
1pxpCK8Cyclin-dependent kinase 22.7.11.220.550
2vv9IM9Cyclin-dependent kinase 22.7.11.220.550
3qrtX14Cyclin-dependent kinase 22.7.11.220.550
2wxvWXVCyclin-dependent kinase 22.7.11.220.549
3qzgX67Cyclin-dependent kinase 22.7.11.220.549
3ql8X01Cyclin-dependent kinase 22.7.11.220.548
3sqq99ZCyclin-dependent kinase 22.7.11.220.548
1pxlCK4Cyclin-dependent kinase 22.7.11.220.547
4acm7YGCyclin-dependent kinase 22.7.11.220.547
2r3jSCJCyclin-dependent kinase 22.7.11.220.546
4ek610KCyclin-dependent kinase 22.7.11.220.546
4fkt48KCyclin-dependent kinase 22.7.11.220.546
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.545
1aq1STUCyclin-dependent kinase 22.7.11.220.544
1oguST8Cyclin-dependent kinase 22.7.11.220.544
2vthLZ2Cyclin-dependent kinase 22.7.11.220.544
3qtuX44Cyclin-dependent kinase 22.7.11.220.544
1vyw292Cyclin-dependent kinase 22.7.11.220.543
2uzbC75Cyclin-dependent kinase 22.7.11.220.543
3qwkX62Cyclin-dependent kinase 22.7.11.220.543
4bgh3I6Cyclin-dependent kinase 22.7.11.220.543
3ezrEZRCyclin-dependent kinase 22.7.11.220.542
3wblPDYCyclin-dependent kinase 22.7.11.220.542
1h1s4SPCyclin-dependent kinase 22.7.11.220.540
1y8yCT7Cyclin-dependent kinase 22.7.11.220.540
2w05FRTCyclin-dependent kinase 22.7.11.220.540
2w06FRVCyclin-dependent kinase 22.7.11.220.540
3r6xX84Cyclin-dependent kinase 22.7.11.220.540
2uzoC62Cyclin-dependent kinase 22.7.11.220.539
4bcpT3CCyclin-dependent kinase 22.7.11.220.539
1v0oINRCell division control protein 2 homolog2.7.11.220.538
3fz1B98Cyclin-dependent kinase 22.7.11.220.538
3le62BZCyclin-dependent kinase 22.7.11.220.538
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.538
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.537
3ddpRC8Cyclin-dependent kinase 22.7.11.220.537
3r7uX96Cyclin-dependent kinase 22.7.11.220.537
3rm618ZCyclin-dependent kinase 22.7.11.220.537
4fko20KCyclin-dependent kinase 22.7.11.220.537
1oiyN41Cyclin-dependent kinase 22.7.11.220.536
2cchATPCyclin-dependent kinase 22.7.11.220.536
4eomATPCyclin-dependent kinase 22.7.11.220.536
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.535
3r28XA0Cyclin-dependent kinase 22.7.11.220.535
2vtrLZBCyclin-dependent kinase 22.7.11.220.534
3py0SU9Cyclin-dependent kinase 22.7.11.220.534
3r1sX73Cyclin-dependent kinase 22.7.11.220.534
2c6o4SPCyclin-dependent kinase 22.7.11.220.533
2r3kSCQCyclin-dependent kinase 22.7.11.220.533
3sw719KCyclin-dependent kinase 22.7.11.220.533
1g5sI17Cyclin-dependent kinase 22.7.11.220.532
1ykr628Cyclin-dependent kinase 22.7.11.220.532
2b52D42Cyclin-dependent kinase 22.7.11.220.532
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.532
3r73X87Cyclin-dependent kinase 22.7.11.220.532
1gij2PUCyclin-dependent kinase 22.7.11.220.531
1oi9N20Cyclin-dependent kinase 22.7.11.220.531
2vu3LZECyclin-dependent kinase 22.7.11.220.531
2eufLQQCyclin-dependent kinase 62.7.11.220.530
2iw94SPCyclin-dependent kinase 22.7.11.220.530
3ezvEZVCyclin-dependent kinase 22.7.11.220.529
1pxkCK3Cyclin-dependent kinase 22.7.11.220.527
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.527
3sw418KCyclin-dependent kinase 22.7.11.220.526
4fkg4CKCyclin-dependent kinase 22.7.11.220.526
1di8DTQCyclin-dependent kinase 22.7.11.220.525
2j9mPY8Cyclin-dependent kinase 22.7.11.220.525
3my5RFZCyclin-dependent kinase 22.7.11.220.525
4ez30S0Cyclin-dependent kinase 22.7.11.220.525
4fkpLS5Cyclin-dependent kinase 22.7.11.220.525
1ke6LS2Cyclin-dependent kinase 22.7.11.220.524
4aua4AUCyclin-dependent kinase 62.7.11.220.524
2b53D23Cyclin-dependent kinase 22.7.11.220.523
2c6iDT1Cyclin-dependent kinase 22.7.11.220.523
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.523
1e9hINRCyclin-dependent kinase 22.7.11.220.522
2bkzSBCCyclin-dependent kinase 22.7.11.220.522
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.522
3lfqA28Cyclin-dependent kinase 22.7.11.220.522
3qziX72Cyclin-dependent kinase 22.7.11.220.522
1vyzN5BCyclin-dependent kinase 22.7.11.220.521
2a0cCK9Cyclin-dependent kinase 22.7.11.220.521
3rpy27ZCyclin-dependent kinase 22.7.11.220.521
1oiqHDUCyclin-dependent kinase 22.7.11.220.520
2vttLZDCyclin-dependent kinase 22.7.11.220.520
3rjc06ZCyclin-dependent kinase 22.7.11.220.520
4cfnJYMCyclin-dependent kinase 22.7.11.220.520
1ke7LS3Cyclin-dependent kinase 22.7.11.220.519
4qmpDKISerine/threonine-protein kinase 242.7.11.10.519
1pxmCK5Cyclin-dependent kinase 22.7.11.220.518
3qtwX3ACyclin-dependent kinase 22.7.11.220.518
3r71X86Cyclin-dependent kinase 22.7.11.220.518
1ke8LS4Cyclin-dependent kinase 22.7.11.220.517
3r7iX9ICyclin-dependent kinase 22.7.11.220.517
1h1r6CPCyclin-dependent kinase 22.7.11.220.515
3bhtMFRCyclin-dependent kinase 22.7.11.220.515
3iggEFQCyclin-dependent kinase 22.7.11.220.515
3r8zZ63Cyclin-dependent kinase 22.7.11.220.515
3qwjX6ACyclin-dependent kinase 22.7.11.220.514
4bcoT6QCyclin-dependent kinase 22.7.11.220.514
1r78FMDCyclin-dependent kinase 22.7.11.220.513
3r7yZ04Cyclin-dependent kinase 22.7.11.220.513
3tnwF18Cyclin-dependent kinase 22.7.11.220.513
4lyn1YGCyclin-dependent kinase 22.7.11.220.513
2xikJ60Serine/threonine-protein kinase 252.7.11.10.512
1oiuN76Cyclin-dependent kinase 22.7.11.220.511
2c6lDT4Cyclin-dependent kinase 22.7.11.220.511
4bcqTJFCyclin-dependent kinase 22.7.11.220.511
2pvnP63Casein kinase II subunit alpha2.7.11.10.509
3ddqRRCCyclin-dependent kinase 22.7.11.220.509
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.509
1gii1PUCyclin-dependent kinase 22.7.11.220.508
2r3iSCFCyclin-dependent kinase 22.7.11.220.508
4fkq42KCyclin-dependent kinase 22.7.11.220.508
1pxoCK7Cyclin-dependent kinase 22.7.11.220.507
2fvdLIACyclin-dependent kinase 22.7.11.220.507
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.507
3nup3NUCyclin-dependent kinase 62.7.11.220.507
3r9oZ71Cyclin-dependent kinase 22.7.11.220.507
4bcnT9NCyclin-dependent kinase 22.7.11.220.507
3unk0BYCyclin-dependent kinase 22.7.11.220.506
4bchT7ZCyclin-dependent kinase 92.7.11.220.506
1ke5LS1Cyclin-dependent kinase 22.7.11.220.505
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.505
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.505
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.504
3pj8404Cyclin-dependent kinase 22.7.11.220.503
3lfnA27Cyclin-dependent kinase 22.7.11.220.502
1unlRRCCyclin-dependent-like kinase 52.7.11.10.501
1urwI1PCyclin-dependent kinase 22.7.11.220.501
2r3r6SCCyclin-dependent kinase 22.7.11.220.501
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.501
3qtrX36Cyclin-dependent kinase 22.7.11.220.501
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.501
4bcmT7ZCyclin-dependent kinase 22.7.11.220.500
4fki09KCyclin-dependent kinase 22.7.11.220.499
3r1yX76Cyclin-dependent kinase 22.7.11.220.498
3raiX85Cyclin-dependent kinase 22.7.11.220.498
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.497
4qmySTUSerine/threonine-protein kinase 242.7.11.10.497
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.496
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.496
1h1q2A6Cyclin-dependent kinase 22.7.11.220.495
3r7eX88Cyclin-dependent kinase 22.7.11.220.495
3tn8F18Cyclin-dependent kinase 92.7.11.220.495
2btrU73Cyclin-dependent kinase 22.7.11.220.494
4qmzB49Serine/threonine-protein kinase 242.7.11.10.494
3ig7EFPCyclin-dependent kinase 22.7.11.220.493
1finATPCyclin-dependent kinase 22.7.11.220.492
2c6mDT5Cyclin-dependent kinase 22.7.11.220.492
3rzb02ZCyclin-dependent kinase 22.7.11.220.492
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.492
4eol1ROCyclin-dependent kinase 22.7.11.220.492
3blrCPBCyclin-dependent kinase 92.7.11.220.491
4loqSB4Mitogen-activated protein kinase 14/0.491
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.490
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.490
3i60E86Mitogen-activated protein kinase 12.7.11.240.490
4fkj11KCyclin-dependent kinase 22.7.11.220.490
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.490
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.489
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.489
2ds11CDCyclin-dependent kinase 22.7.11.220.488
2vtqLZACyclin-dependent kinase 22.7.11.220.488
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.488
3qzhX69Cyclin-dependent kinase 22.7.11.220.488
2c6kDT2Cyclin-dependent kinase 22.7.11.220.487
3dogNNNCyclin-dependent kinase 22.7.11.220.487
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.487
1h1pCMGCyclin-dependent kinase 22.7.11.220.486
1vikBAYGag-Pol polyprotein/0.486
1xjdSTUProtein kinase C theta type2.7.11.130.486
2r3mSCXCyclin-dependent kinase 22.7.11.220.486
2xnbY8LCyclin-dependent kinase 22.7.11.220.486
2zjwREFCasein kinase II subunit alpha2.7.11.10.486
4eor4SPCyclin-dependent kinase 22.7.11.220.486
1ia3TQ5Dihydrofolate reductase1.5.1.30.485
2f2cAP9Cyclin-dependent kinase 62.7.11.220.485
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.485
3pxyJWSCyclin-dependent kinase 22.7.11.220.484
1v0pPVBCell division control protein 2 homolog2.7.11.220.483
3mb601ICasein kinase II subunit alpha2.7.11.10.483
3qqlX03Cyclin-dependent kinase 22.7.11.220.483
3qx4X4BCyclin-dependent kinase 22.7.11.220.483
4eos1ROCyclin-dependent kinase 22.7.11.220.483
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
2b55D31Cyclin-dependent kinase 22.7.11.220.482
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.482
3be9P04Casein kinase II subunit alpha2.7.11.10.482
4lopSB4Mitogen-activated protein kinase 14/0.482
2b54D05Cyclin-dependent kinase 22.7.11.220.481
4eooATPCyclin-dependent kinase 22.7.11.220.481
4jr7GNPCasein kinase II subunit alpha2.7.11.10.481
2vagV25Dual specificity protein kinase CLK12.7.12.10.480
3qruX19Cyclin-dependent kinase 22.7.11.220.480
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.480
2wipP49Cyclin-dependent kinase 22.7.11.220.479
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.479
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.479
4hvh19RTyrosine-protein kinase JAK32.7.10.20.479
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.478
2chlDKICasein kinase I isoform gamma-32.7.11.10.478
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.478
3bheBZNGag-Pol polyprotein3.4.23.160.478
3r8pZ46Cyclin-dependent kinase 22.7.11.220.478
4dgnLU2Casein kinase II subunit alpha2.7.11.10.478
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.478
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.477
2r3o2SCCyclin-dependent kinase 22.7.11.220.477
2w1hL0FCyclin-dependent kinase 22.7.11.220.477
3linE13Protease/0.477
3toh079Gag-Pol polyprotein2.7.7.490.477
4au8Z3RCyclin-dependent-like kinase 52.7.11.10.477
4btjADPTau-tubulin kinase 12.7.11.10.477
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
5e8wSTUTGF-beta receptor type-12.7.11.300.476
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.475
3nynSGVG protein-coupled receptor kinase 62.7.11.160.475
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
1xddAAYIntegrin alpha-L/0.474
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.474
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.474
2vtsLZCCyclin-dependent kinase 22.7.11.220.474
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.474
4ogrADNCyclin-dependent kinase 92.7.11.220.474
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.473
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.473
1om1IQACasein kinase II subunit alpha2.7.11.10.472
1unhIXMCyclin-dependent-like kinase 52.7.11.10.472
1vjy460TGF-beta receptor type-12.7.11.300.472
3rm719ZCyclin-dependent kinase 22.7.11.220.472
1csnATPCasein kinase I homolog 12.7.11.10.471
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.471
1xl2189Gag-Pol polyprotein3.4.23.160.471
2izsBRQCasein kinase I isoform gamma-32.7.11.10.471
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.471
3orkAGSSerine/threonine protein kinase/0.471
4btjATPTau-tubulin kinase 12.7.11.10.471
4dgmAGICasein kinase II subunit alpha2.7.11.10.471
4eop1ROCyclin-dependent kinase 22.7.11.220.471
4mwhATPCasein kinase II subunit alpha2.7.11.10.471
1m0b0ZQGag-Pol polyprotein3.4.23.160.470
4g170VNCasein kinase I isoform gamma-32.7.11.10.470
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.470
3s00Z60Cyclin-dependent kinase 22.7.11.220.469
4e4m0NHTyrosine-protein kinase JAK2/0.469
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.469
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.468
3nux3NVCyclin-dependent kinase 62.7.11.220.468
3r83Z14Cyclin-dependent kinase 22.7.11.220.468
3unj0BXCyclin-dependent kinase 22.7.11.220.468
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.468
3c50ADPRhodopsin kinase/0.467
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.467
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.467
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.467
2ghlLIBMitogen-activated protein kinase 14/0.466
2pvhP19Casein kinase II subunit alpha2.7.11.10.466
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.466
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.465
1b39ATPCyclin-dependent kinase 22.7.11.220.464
1eh4IC1Casein kinase I homolog 12.7.11.10.464
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.464
3el51UNGag-Pol polyprotein/0.464
3jziJZLBiotin carboxylase6.3.4.140.464
5dr6SKEAurora kinase A2.7.11.10.464
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.463
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.463
1cqp803Integrin alpha-L/0.462
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.462
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.462
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
3qqhX0ACyclin-dependent kinase 22.7.11.220.462
3rpo24ZCyclin-dependent kinase 22.7.11.220.462
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.462
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.462
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.462
5cvhADPCasein kinase II subunit alpha2.7.11.10.462
1tj0FADBifunctional protein PutA1.5.5.20.461
2c5yMTWCyclin-dependent kinase 22.7.11.220.461
2fxdDR7Pol polyprotein/0.461
2zbaZBATrichothecene 3-O-acetyltransferase/0.461
3e2sFADBifunctional protein PutA1.5.5.20.461
3qqgX06Cyclin-dependent kinase 22.7.11.220.461
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.461
4gmy0X5Tyrosine-protein kinase JAK2/0.461
4nj32KDCyclin-dependent kinase 22.7.11.220.461
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.460
2a4lRRCCyclin-dependent kinase 22.7.11.220.460
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.460
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.460
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.460
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.460
3gxlQIGTGF-beta receptor type-12.7.11.300.460
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.460
3lzs017Gag-Pol polyprotein3.4.23.160.460
3r7vZ02Cyclin-dependent kinase 22.7.11.220.460
3sf6FDAGlutaryl-CoA dehydrogenase/0.460
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.460
4gub0Y4Casein kinase II subunit alpha2.7.11.10.460
2pvlP55Casein kinase II subunit alpha2.7.11.10.459
2qo9ANPEphrin type-A receptor 32.7.10.10.459
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.459
4aqc88ATyrosine-protein kinase JAK2/0.459
4eoi1ROCyclin-dependent kinase 22.7.11.220.459
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.459
4zseANPEpidermal growth factor receptor2.7.10.10.459
2c69CT8Cyclin-dependent kinase 22.7.11.220.458
3ggfGVDSerine/threonine-protein kinase 26/0.458
3zdu38RCyclin-dependent kinase-like 32.7.11.220.458
3zh8C58Protein kinase C iota type2.7.11.130.458
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.458
4fi1ATPCasein kinase II subunit alpha2.7.11.10.458
1jstATPCyclin-dependent kinase 22.7.11.220.457
2dwbANPAurora kinase A2.7.11.10.457
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.457
4jqeANPCasein kinase II subunit alpha2.7.11.10.457
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.456
2ejzSAHDiphthine synthase/0.456
2ovhAS0Progesterone receptor/0.456
3eyhIZATyrosine-protein kinase JAK1/0.456
3gu6ADPDeath-associated protein kinase 12.7.11.10.456
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.456
3oxcROCProtease/0.456
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.456
4ivc1J6Tyrosine-protein kinase JAK1/0.456
4j97ACPFibroblast growth factor receptor 2/0.456
4ktc1X3Genome polyprotein3.4.21.980.456
4yaoFMNNADPH--cytochrome P450 reductase/0.456
4yuqKS1Calmodulin-like domain protein kinase/0.456
1hihC20Gag-Pol polyprotein/0.455
2bpz3INGag-Pol polyprotein3.4.23.160.455
2w1fL0FAurora kinase A2.7.11.10.455
3begANPSRSF protein kinase 12.7.11.10.455
3mtfA3FActivin receptor type-12.7.11.300.455
3t8oATPRhodopsin kinase/0.455
4dymIYZActivin receptor type-12.7.11.300.455
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.455
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.455
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.454
2bktRPFRenin3.4.23.150.454
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.454
3gubGUBDeath-associated protein kinase 12.7.11.10.454
3r8uZ31Cyclin-dependent kinase 22.7.11.220.454
4dgo0JWCasein kinase II subunit alpha2.7.11.10.454
5d3qGDPDynamin-13.6.5.50.454
1c70L75Protease/0.453
1hpxKNIGag-Pol polyprotein/0.453
1rfuADPPyridoxal kinase2.7.1.350.453
2b7aIZATyrosine-protein kinase JAK2/0.453
2pb6SAHDiphthine synthase/0.453
2pmlANPUncharacterized protein/0.453
3c4zADPRhodopsin kinase/0.453
3pe2E1BCasein kinase II subunit alpha2.7.11.10.453
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.453
4fv6E57Mitogen-activated protein kinase 12.7.11.240.453
4lfiGNPCasein kinase II subunit alpha2.7.11.10.453
1h0w207Cyclin-dependent kinase 22.7.11.220.452
2ien017Gag-Pol polyprotein3.4.23.160.452
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.452
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.452
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.452
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.452
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.452
4enhFVXCholesterol 24-hydroxylase/0.452
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.452
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.452
2ek7SAHDiphthine synthase/0.451
2he5NDPAldo-keto reductase family 1 member C211.1.10.451
2q641UNGag-Pol polyprotein3.4.23.160.451
3bbrBHYGlutamate receptor 2/0.451
3hx4ANPCalmodulin-domain protein kinase 1/0.451
3q9zTXQCasein kinase II subunit alpha2.7.11.10.451
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.451
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4ewhT77Activated CDC42 kinase 1/0.451
4jhz1KVBeta-glucuronidase3.2.1.310.451
4qmlANPSerine/threonine-protein kinase 242.7.11.10.451
1uy7PU4Heat shock protein HSP 90-alpha/0.450
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.450
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.450
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.450
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.450
3sheI85MAP kinase-activated protein kinase 32.7.11.10.450
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.450
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.450
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.450
1lp4ANPCasein kinase II subunit alpha2.7.11.10.449
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.449
2owkSAHDiphthine synthase/0.449
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.449
3lq5SLQCyclin-dependent kinase 92.7.11.220.449
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.449
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.449
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.449
4hge15VTyrosine-protein kinase JAK2/0.449
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.449
1r2jFADFkbI/0.448
2p3b3TLV-1 PROTEASE protein/0.448
2p3b3TLV-1 protease/0.448
2qi5MZ7Gag-Pol polyprotein/0.448
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.448
2w1gL0GAurora kinase A2.7.11.10.448
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.448
3r8lZ30Cyclin-dependent kinase 22.7.11.220.448
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.448
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.448
4rrrA3TThreonine--tRNA ligase6.1.1.30.448
4y9lFADAcyl-CoA dehydrogenase family member 11/0.448
1gvt2ZSEndothiapepsin3.4.23.220.447
1hiiC20Gag-Pol polyprotein/0.447
1k2c0Q4Gag-Pol polyprotein3.4.23.160.447
1m2rMNYCasein kinase II subunit alpha2.7.11.10.447
1zeoC01Peroxisome proliferator-activated receptor gamma/0.447
2c4g514Cyclin-dependent kinase 22.7.11.220.447
2ed3SAHDiphthine synthase/0.447
2p6lSAHDiphthine synthase/0.447
2pmnK51Protein kinase 7/0.447
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.447
3bgcLJHGag-Pol polyprotein3.4.23.160.447
3gggNADPrephenate dehydrogenase/0.447
3hmm855TGF-beta receptor type-12.7.11.300.447
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
3pwm017Gag-Pol polyprotein3.4.23.160.447
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.447
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.447
4fmqANPMitogen-activated protein kinase 12.7.11.240.447
4i8zG08Gag-Pol polyprotein3.4.23.160.447
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.447
4qbjNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.447
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.446
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.446
2fznFADBifunctional protein PutA1.5.5.20.446
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.446
2j9gANPBiotin carboxylase6.3.4.140.446
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.446
3a3gDLZLumazine protein/0.446
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3gu7ADPDeath-associated protein kinase 12.7.11.10.446
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.446
3nwq2NCGag-Pol polyprotein3.4.23.160.446
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.446
3zep1NXTyrosine-protein kinase JAK32.7.10.20.446
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.446
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.446
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
2r5q1UNGag-Pol polyprotein/0.445
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.445
3a9wNADNDP-sugar epimerase/0.445
3ekyDR7Gag-Pol polyprotein3.4.23.160.445
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.445
4bgg844Activin receptor type-12.7.11.300.445
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.445
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.445
1gy3ATPCyclin-dependent kinase 22.7.11.220.444
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.444
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.444
1phhFADp-hydroxybenzoate hydroxylase/0.444
2bfyH1NAurora kinase B-A2.7.11.10.444
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.444
3litE15Protease/0.444
3ortAGSSerine/threonine protein kinase/0.444
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.444
4hgt15GCasein kinase I isoform delta2.7.11.10.444
4hvi19STyrosine-protein kinase JAK32.7.10.20.444
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.444
5dpvSKEAurora kinase A2.7.11.10.444
1a8g2Z4Gag-Pol polyprotein3.4.23.160.443
1bygSTUTyrosine-protein kinase CSK/0.443
1mrwK57Gag-Pol polyprotein3.4.23.160.443
2avvMK1Gag-Pol polyprotein3.4.23.160.443
2ed5SAHDiphthine synthase/0.443
2z6iFMN2-nitropropane dioxygenase/0.443
3cgfJNFMitogen-activated protein kinase 102.7.11.240.443
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.443
3efwAK8Aurora kinase A2.7.11.10.443
3ekx1UNGag-Pol polyprotein3.4.23.160.443
3elySAHMethyltransferase/0.443
3k1wBFXRenin3.4.23.150.443
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.443
3r8vZ62Cyclin-dependent kinase 22.7.11.220.443
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.443
4anmWULCasein kinase II subunit alpha2.7.11.10.443
4c4jX21Dual specificity protein kinase TTK2.7.12.10.443
4c62XWWTyrosine-protein kinase JAK2/0.443
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.443
4o8aFADBifunctional protein PutA1.2.1.880.443
1bim0QBRenin3.4.23.150.442
1dayGNPCasein kinase II subunit alpha2.7.11.10.442
1tj1FADBifunctional protein PutA1.5.5.20.442
1z1hHBBGag-Pol polyprotein3.4.23.160.442
2bpy3INGag-Pol polyprotein3.4.23.160.442
2ekaSAHDiphthine synthase/0.442
2p3c3TLProtease/0.442
2wouZZFTGF-beta receptor type-12.7.11.300.442
2z6rSAHDiphthine synthase/0.442
3a7jADPSerine/threonine-protein kinase 242.7.11.10.442
3gu83GUDeath-associated protein kinase 12.7.11.10.442
3hllI45Mitogen-activated protein kinase 14/0.442
3iok1P6Tyrosine-protein kinase JAK2/0.442
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.442
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.442
3qx2X63Cyclin-dependent kinase 22.7.11.220.442
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.442
4btmF8ETau-tubulin kinase 12.7.11.10.442
4g6oE28Mitogen-activated protein kinase 12.7.11.240.442
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.442
4q73FADBifunctional protein PutA/0.442
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
5dt0SKEAurora kinase A2.7.11.10.442
1n83CLRNuclear receptor ROR-alpha/0.441
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.441
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.441
2pb4SAHDiphthine synthase/0.441
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.441
3pwrROCGag-Pol polyprotein3.4.23.160.441
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.441
4hvg19QTyrosine-protein kinase JAK32.7.10.20.441
4l9i8PRRhodopsin kinase/0.441
4looSB4Mitogen-activated protein kinase 14/0.441
4qgiROCGag-Pol polyprotein3.4.23.160.441
5dn3ATPAurora kinase A2.7.11.10.441
5dt3ATPAurora kinase A2.7.11.10.441
1iziQ50Gag-Pol polyprotein3.4.23.160.440
1xl5190Gag-Pol polyprotein3.4.23.160.440
1z1rHBHGag-Pol polyprotein3.4.23.160.440
2el0SAHDiphthine synthase/0.440
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.440
2ovmAS0Progesterone receptor/0.440
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.440
3el9DR7Gag-Pol polyprotein3.4.23.160.440
3keuATPPyridoxal kinase2.7.1.350.440
3mdmFJZCholesterol 24-hydroxylase/0.440
3nga3NGCasein kinase II subunit alpha2.7.11.10.440
3oom507Activin receptor type-12.7.11.300.440
3zpuM8BGag-Pol polyprotein3.4.23.160.440
4a4qUX9Pol protein/0.440
4hgs15GCasein kinase I isoform gamma-32.7.11.10.440
4i22IREEpidermal growth factor receptor2.7.10.10.440
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.440
4nakPBQ2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic2.7.7.600.440
4nk92K5Fibroblast growth factor receptor 1/0.440
4qnaX11Serine/threonine-protein kinase 242.7.11.10.440