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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1db56INPhospholipase A2, membrane associated

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1db56INPhospholipase A2, membrane associated/1.000
1dcyI3NPhospholipase A2, membrane associated/0.725
1db48INPhospholipase A2, membrane associated/0.668
1kquBR4Phospholipase A2, membrane associated/0.587
3u8hBHPPhospholipase A2, membrane associated/0.569
1aypINBPhospholipase A2, membrane associated/0.560
3u8dU8DPhospholipase A2, membrane associated/0.558
1kvoOAPPhospholipase A2, membrane associated/0.552
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.507
5p2pDHGPhospholipase A2, major isoenzyme3.1.1.40.506
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.476
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.470
4hmbPZZPhospholipase A2 VRV-PL-VIIIa/0.455
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.454
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.451
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441