sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 1.000 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.542 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.522 | |
| 4h1q | 0XX | Matrix metalloproteinase-9 | 3.4.24.35 | 0.517 | |
| 2w0d | CGS | Macrophage metalloelastase | 3.4.24.65 | 0.488 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.484 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.482 | |
| 3ljg | EEF | Macrophage metalloelastase | 3.4.24.65 | 0.482 | |
| 2ovx | 4MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.477 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.476 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.475 | |
| 4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.475 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.471 | |
| 2xs4 | ALA_PHE_THR | Karilysin | 3.4.24 | 0.464 | |
| 2wo8 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.460 | |
| 4h76 | 10B | Macrophage metalloelastase | 3.4.24.65 | 0.459 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.458 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.455 | |
| 4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.455 | |
| 3tsk | QEG | Macrophage metalloelastase | 3.4.24.65 | 0.454 | |
| 1zs0 | EIN | Neutrophil collagenase | 3.4.24.34 | 0.453 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.453 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.450 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.448 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.447 | |
| 3kry | 3KR | Collagenase 3 | 3.4.24 | 0.447 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.446 | |
| 1xh6 | R94 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.445 | |
| 3aig | 0ZC | Snake venom metalloproteinase adamalysin-2 | 3.4.24.46 | 0.445 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.444 | |
| 1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.443 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.442 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.440 |