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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1cdeGARPhosphoribosylglycinamide formyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1cdeGARPhosphoribosylglycinamide formyltransferase/1.000
1c3eGARPhosphoribosylglycinamide formyltransferase/0.579
1c2tGARPhosphoribosylglycinamide formyltransferase/0.555
1jkx138Phosphoribosylglycinamide formyltransferase/0.531
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.473
1rbyGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.473
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.441
2zjmF1MBeta-secretase 13.4.23.460.441
4hgs15GCasein kinase I isoform gamma-32.7.11.10.440