Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1c1wBAHProthrombin3.4.21.5

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1c1wBAHProthrombin3.4.21.51.000
2cf8ESHProthrombin3.4.21.50.499
2cn0F25Prothrombin3.4.21.50.494
2cf9348Prothrombin3.4.21.50.458
1oytFSNProthrombin3.4.21.50.446
1ypeUIPProthrombin3.4.21.50.445
2v3oI26Prothrombin3.4.21.50.445