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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1c1dNAIPhenylalanine dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1c1dNAIPhenylalanine dehydrogenase/1.000
4xgiNADGlutamate dehydrogenase/0.476
3ggoNAIPrephenate dehydrogenase/0.470
3hwrNDP2-dehydropantoate 2-reductase/0.468
5ijzNAPNADP-specific glutamate dehydrogenase1.4.1.40.461
5hwsNAP2-dehydropantoate 2-reductase/0.459
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.454
3wmxNADNAD dependent epimerase/dehydratase/0.452
3cmcNADGlyceraldehyde-3-phosphate dehydrogenase/0.451
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.450
3icrFADCoenzyme A disulfide reductase/0.447
4ajp88NL-lactate dehydrogenase A chain1.1.1.270.447
2g82NADGlyceraldehyde-3-phosphate dehydrogenase/0.446
3ojlNADCap5O/0.446
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.444
3p6pA6BCamphor 5-monooxygenase1.14.15.10.441
1gypNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.440
2f1kNAPPrephenate dehydrogenase/0.440