Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1bxrANPCarbamoyl-phosphate synthase large chain

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1bxrANPCarbamoyl-phosphate synthase large chain/1.000
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
1a9xADPCarbamoyl-phosphate synthase large chain/0.477
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.470
1ig1ANPDeath-associated protein kinase 12.7.11.10.467
3hyoADPPyridoxal kinase/0.467
2yxuATPPyridoxal kinase2.7.1.350.461
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.461
4kcfAKMFAD-dependent oxidoreductase/0.459
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.458
3fhyATPPyridoxal kinase2.7.1.350.458
3oibFDAPutative acyl-CoA dehydrogenase/0.458
4g3pUD1Bifunctional protein GlmU/0.457
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.456
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.456
1rfvADPPyridoxal kinase2.7.1.350.455
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.455
4en4ATPPyridoxal kinase2.7.1.350.455
2ien017Gag-Pol polyprotein3.4.23.160.453
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.453
2ad5ADPCTP synthase/0.452
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
1bcpATPPertussis toxin subunit 4/0.450
1bcpATPPertussis toxin subunit 5/0.450
5bp9SAHPutative methyltransferase protein/0.450
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.449
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.449
4o7lADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.449
3giyFMN(S)-mandelate dehydrogenase1.1.99.310.448
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.448
1esvLARActin, alpha skeletal muscle/0.447
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.446
2bi4NADLactaldehyde reductase1.1.1.770.446
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
1kp3ATPArgininosuccinate synthase6.3.4.50.445
2ftoCB3Thymidylate synthase/0.445
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.445
4l04NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.445
1f4gTP4Thymidylate synthase/0.444
2ql6ADPNicotinamide riboside kinase 1/0.444
3mqe416Prostaglandin G/H synthase 21.14.99.10.444
3q44D50M1 family aminopeptidase3.4.110.444
4j98ACPFibroblast growth factor receptor 2/0.444
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.443
1cf3FADGlucose oxidase1.1.3.40.443
2bl4NADLactaldehyde reductase1.1.1.770.443
2e1zB4PPropionate kinase/0.443
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4l06NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
3dl0AP5Adenylate kinase/0.442
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.442
4ryvZEAProtein LlR18A/0.442
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.441
4y9lFADAcyl-CoA dehydrogenase family member 11/0.441
5ebuFMNLactate oxidase/0.441
1s3zCOAAminoglycoside N(6')-acetyltransferase type 1/0.440
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.440
3qyw6PBMitogen-activated protein kinase 12.7.11.240.440