sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 1.000 | |
| 4psw | COA | Histone acetyltransferase type B catalytic subunit | / | 0.576 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.504 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.502 | |
| 4psx | COA | Histone acetyltransferase type B catalytic subunit | / | 0.493 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.483 | |
| 1s7l | COA | Acetyl transferase | / | 0.481 | |
| 2zw5 | COA | Bleomycin acetyltransferase | / | 0.477 | |
| 3d2p | COA | Amino-acid acetyltransferase | / | 0.477 | |
| 3r95 | ACO | MccE protein | / | 0.476 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.475 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.474 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.473 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.471 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.465 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.463 | |
| 3fbu | COA | Acetyltransferase, GNAT family | / | 0.463 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.461 | |
| 2zw4 | COA | Bleomycin acetyltransferase | / | 0.461 | |
| 1yre | COA | Uncharacterized protein | / | 0.457 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.457 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.456 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.455 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.455 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.454 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.453 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.452 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.451 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.451 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.449 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.449 | |
| 1s7n | COA | Acetyl transferase | / | 0.448 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.447 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.446 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.444 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.440 |