sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.516 | |
| 1bl7 | SB4 | Mitogen-activated protein kinase 14 | / | 0.511 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.502 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.498 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.495 | |
| 3ha8 | 5JZ | Mitogen-activated protein kinase 14 | / | 0.490 | |
| 4eh5 | 0OM | Mitogen-activated protein kinase 14 | / | 0.487 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.485 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 1bmk | SB5 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.479 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 3fml | FML | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 2zaz | GK1 | Mitogen-activated protein kinase 14 | / | 0.476 | |
| 3fmj | FMJ | Mitogen-activated protein kinase 14 | / | 0.476 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.462 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1m7q | DQO | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 1oz1 | FPH | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.452 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.450 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4dlj | 6RG | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.448 | |
| 1w7h | 3IP | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3fmn | 530 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4ei7 | GDP | Plasmid replication protein RepX | / | 0.447 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.445 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.443 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1w84 | L12 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.442 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.441 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.441 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 3flq | 891 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.440 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.440 |