sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1bdm | NAX | Malate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1bdm | NAX | Malate dehydrogenase | / | 1.000 | |
| 1bmd | NAD | Malate dehydrogenase | / | 0.582 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.558 | |
| 2cvq | NDP | Malate dehydrogenase | / | 0.531 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.507 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.503 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.499 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.498 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.496 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.482 | |
| 1llq | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.481 | |
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.477 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.475 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.461 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.457 | |
| 1y7t | NDP | Malate dehydrogenase | / | 0.454 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.454 | |
| 4uun | NAI | L-lactate dehydrogenase | / | 0.448 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.446 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.445 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.441 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.441 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 |