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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1b8oIMHPurine nucleoside phosphorylase2.4.2.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1b8oIMHPurine nucleoside phosphorylase2.4.2.11.000
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.735
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.659
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.650
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.630
1b8nIMGPurine nucleoside phosphorylase2.4.2.10.626
1rszDIHPurine nucleoside phosphorylase2.4.2.10.617
3k8q22APurine nucleoside phosphorylase2.4.2.10.586
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.581
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.575
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.569
1yryMSGPurine nucleoside phosphorylase2.4.2.10.555
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.554
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.552
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.537
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.533
1v453DGPurine nucleoside phosphorylase2.4.2.10.532
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.531
4earIM5Purine nucleoside phosphorylase2.4.2.10.531
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.518
4cdmFO1Deoxyribodipyrimidine photolyase/0.517
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.516
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.515
3k8o229Purine nucleoside phosphorylase2.4.2.10.512
4bfuZVUPantothenate kinase2.7.1.330.511
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.509
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.507
1pf7IMHPurine nucleoside phosphorylase2.4.2.10.504
1rctNOSPurine nucleoside phosphorylase2.4.2.10.504
2cekN8TAcetylcholinesterase3.1.1.70.504
2p4sDIHAGAP005945-PA/0.502
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.501
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.500
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.499
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.498
1fmjRTLRetinol dehydratase/0.495
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.495
3p74FMNPentaerythritol tetranitrate reductase/0.494
4bfvZVVPantothenate kinase2.7.1.330.494
1a9cGTPGTP cyclohydrolase 13.5.4.160.493
1o9bNAIQuinate/shikimate dehydrogenase/0.493
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.493
1tkaN3TTransketolase 12.2.1.10.492
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.492
4arbC57Acetylcholinesterase3.1.1.70.492
3zoiM2WIsopenicillin N synthase1.21.3.10.491
1q83TZ5Acetylcholinesterase3.1.1.70.490
2aouCQAHistamine N-methyltransferase2.1.1.80.490
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.490
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.489
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
3p80P80Pentaerythritol tetranitrate reductase/0.489
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.489
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.489
4a81DXCMajor pollen allergen Bet v 1-A/0.489
1nw4IMHPurine nucleoside phosphorylase/0.488
2ejzSAHDiphthine synthase/0.488
1itzTPPTransketolase, chloroplastic2.2.1.10.487
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.487
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
4a83DXCMajor pollen allergen Bet v 1-A/0.487
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
2jb4A14Isopenicillin N synthase1.21.3.10.486
1bk0ACVIsopenicillin N synthase1.21.3.10.485
1x1bSAHC-20 methyltransferase/0.485
2vbdV10Isopenicillin N synthase1.21.3.10.485
3fr5I4AFatty acid-binding protein, adipocyte/0.485
3qeoLLTDeoxycytidine kinase2.7.1.740.485
4oztP1AEcdysone receptor, putative/0.485
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.484
4ey6GNTAcetylcholinesterase3.1.1.70.484
2gv8NDPThiol-specific monooxygenase1.14.130.483
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.483
3ekuCY9Actin-5C/0.483
1h50FMNPentaerythritol tetranitrate reductase/0.482
1h61PDNPentaerythritol tetranitrate reductase/0.482
2gyuHI6Acetylcholinesterase3.1.1.70.482
2iviACWIsopenicillin N synthase1.21.3.10.482
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
3gncQQQGlutaryl-CoA dehydrogenase/0.482
4d7eFADPutative lysine-N-oxygenase/0.482
4rvgTYDD-mycarose 3-C-methyltransferase/0.482
2qimZEAClass 10 plant pathogenesis-related protein/0.481
3fktSIIBeta-secretase 13.4.23.460.481
3zv7NHGAcetylcholinesterase3.1.1.70.481
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.480
1x8lOXRRetinol dehydratase/0.480
2dxdANPNucleoside diphosphate kinase2.7.4.60.480
3f03FMNPentaerythritol tetranitrate reductase/0.480
3h3qH13Collagen type IV alpha-3-binding protein/0.480
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.480
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.479
1hb1OCVIsopenicillin N synthase1.21.3.10.479
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.479
1jdzFMBPurine nucleoside phosphorylase/0.479
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.479
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.479
1h22E10Acetylcholinesterase3.1.1.70.478
1pqc444Oxysterols receptor LXR-beta/0.478
1rzuADPGlycogen synthase 12.4.1.210.478
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.478
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
3h3r14HCollagen type IV alpha-3-binding protein/0.478
3q9bB3NAcetylpolyamine amidohydrolase/0.478
4a87NARMajor pollen allergen Bet v 1-A/0.478
4g8jTHMUridine phosphorylase/0.478
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.478
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.477
2fxuBIDActin, alpha skeletal muscle/0.477
2xufTZ4Acetylcholinesterase3.1.1.70.477
3nzpPLPArginine decarboxylase/0.477
3ohh3HHBeta-secretase 13.4.23.460.477
3v2uATPProtein GAL3/0.477
4b4w9L9Bifunctional protein FolD/0.477
4bfzZVZPantothenate kinase2.7.1.330.477
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.477
1je1GMPPurine nucleoside phosphorylase/0.476
1obnASVIsopenicillin N synthase1.21.3.10.476
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.476
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.476
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.476
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.476
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.476
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.476
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.475
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.475
3ufl508Beta-secretase 13.4.23.460.475
4lh71X8DNA ligase/0.475
7stdCRPScytalone dehydratase4.2.1.940.475
1nj6A5AProline--tRNA ligase/0.474
2c20NADUDP-glucose 4-epimerase/0.474
3ko8NADNAD-dependent epimerase/dehydratase/0.474
3wqmB29Diterpene synthase3.1.7.80.474
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.474
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.474
1h60STRPentaerythritol tetranitrate reductase/0.473
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.473
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.473
1trgCB3Thymidylate synthase/0.473
2xuoTZ4Acetylcholinesterase3.1.1.70.473
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.473
4c49HCYCorticosteroid-binding globulin/0.473
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.473
5dp2NAPCurF/0.473
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.472
1v2hGUNPurine nucleoside phosphorylase2.4.2.10.472
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.472
2rd2QSIGlutamine--tRNA ligase6.1.1.180.472
2yj5ATPCopper-transporting ATPase/0.472
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.472
4jq4IMNAldo-keto reductase family 1 member C2/0.472
4zqcF6FTryptophan synthase alpha chain/0.472
1r2jFADFkbI/0.471
1vgqCAOFormyl-CoA:oxalate CoA-transferase/0.471
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.471
2rehFADNitroalkane oxidase1.7.3.10.471
2vn1FK5Peptidylprolyl isomerase/0.471
2x90EALAngiotensin-converting enzyme3.4.15.10.471
3eksCY9Actin-5C/0.471
3phiNDPShikimate dehydrogenase (NADP(+))/0.471
4m0f1YKAcetylcholinesterase3.1.1.70.471
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.471
5irnADPNucleotide binding oligomerization domain containing 2/0.471
1k7fIAVTryptophan synthase alpha chain/0.470
1tilATPAnti-sigma F factor/0.470
1u1f183Uridine phosphorylase2.4.2.30.470
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.470
3pm1ETHTH-type transcriptional regulator QacR/0.470
4a86H35Major pollen allergen Bet v 1-A/0.470
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.470
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.469
1fxsNAPGDP-L-fucose synthase/0.469
1icsFMN12-oxophytodienoate reductase 11.3.1.420.469
1ja0FADNADPH--cytochrome P450 reductase/0.469
2fonFADAcyl-coenzyme A oxidase/0.469
3kej3EJCollagenase 33.4.240.469
3p62FMNPentaerythritol tetranitrate reductase/0.469
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
4h9tHL4Phosphotriesterase/0.469
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.469
4ubuCOASteroid 3-ketoacyl-CoA thiolase/0.469
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.469
1j78VDYVitamin D-binding protein/0.468
1ja1FMNNADPH--cytochrome P450 reductase/0.468
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
2bu9HFVIsopenicillin N synthase1.21.3.10.468
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.468
2y6fM9FIsopenicillin N synthase1.21.3.10.468
2zsiGA4Gibberellin receptor GID1A30.468
3ske054Genome polyprotein2.7.7.480.468
4b7zQ4QAcetylcholinesterase3.1.1.70.468
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.468
4tl9AGSCircadian clock protein kinase KaiC2.7.11.10.468
4wljIK2Kynurenine--oxoglutarate transaminase 12.6.1.70.468
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.468
2ea4F79Methionine aminopeptidase 2/0.467
2g8yNADHydroxycarboxylate dehydrogenase B/0.467
2jf0HBPAcetylcholinesterase3.1.1.70.467
2y60M8FIsopenicillin N synthase1.21.3.10.467
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.467
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.467
4tlaADPCircadian clock protein kinase KaiC2.7.11.10.467
4x28FDAAcyl-CoA dehydrogenase FadE26/0.467
4x28FDAAcyl-CoA dehydrogenase FadE27/0.467
1ahgTYR_PLPAspartate aminotransferase2.6.1.10.466
1e2nRCAThymidine kinase/0.466
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.466
1h51FMNPentaerythritol tetranitrate reductase/0.466
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.466
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.466
2vatCOAAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.466
2w6cBM4Acetylcholinesterase3.1.1.70.466
2zi53L1Deoxycytidine kinase2.7.1.740.466
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.466
4a8v2ANMajor pollen allergen Bet v 1-J/0.466
4bfxZVXPantothenate kinase2.7.1.330.466
4esoNAPPutative oxidoreductase/0.466
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.466
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.466
5stdUNNScytalone dehydratase4.2.1.940.466
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.465
1q84TZ4Acetylcholinesterase3.1.1.70.465
1r5hAO2Methionine aminopeptidase 2/0.465
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.465
2b58COADiamine acetyltransferase 1/0.465
2uxiG50HTH-type transcriptional regulator TtgR/0.465
2x97RX4Angiotensin-converting enzyme3.4.15.10.465
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
3imeBZ2Pantothenate synthetase6.3.2.10.465
3mjrAC2Deoxycytidine kinase2.7.1.740.465
3vg10GTBeta-secretase 13.4.23.460.465
4araC56Acetylcholinesterase3.1.1.70.465
1e66HUXAcetylcholinesterase3.1.1.70.464
1icqOPD12-oxophytodienoate reductase 11.3.1.420.464
1odcA8BAcetylcholinesterase3.1.1.70.464
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
1zgcA2EAcetylcholinesterase3.1.1.70.464
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.464
2g1o2IGRenin3.4.23.150.464
2hp2KE4Glutamate-1-semialdehyde 2,1-aminomutase5.4.3.80.464
2q92B23Methionine aminopeptidase/0.464
2xi4AFTAcetylcholinesterase3.1.1.70.464
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.464
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.464
4tlcAGSCircadian clock protein kinase KaiC2.7.11.10.464
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.464
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.463
2g0bNLTLong-chain N-acyl amino acid synthase/0.463
2gjnFMNNitronate monooxygenase1.13.12.160.463
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.463
2hpvFMNFMN-dependent NADH-azoreductase1.70.463
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.463
2whqHI6Acetylcholinesterase3.1.1.70.463
2xukTZ5Acetylcholinesterase3.1.1.70.463
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.463
3cv9VDXVitamin D3 dihydroxylase/0.463
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.463
3mo0SAHHistone-lysine N-methyltransferase EHMT1/0.463
3ojxFMNNADPH--cytochrome P450 reductase/0.463
4dk70KSOxysterols receptor LXR-beta/0.463
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.463
4nv14TGFormyl transferase/0.463
1h36R88Squalene--hopene cyclase4.2.1.1290.462
1jdtMTAPurine nucleoside phosphorylase/0.462
1rsgFADPolyamine oxidase FMS1/0.462
1txtCAAHMG-CoA synthase/0.462
2dsgSAHDiphthine synthase/0.462
2x0fTRHWsaF/0.462
2xupTZ5Acetylcholinesterase3.1.1.70.462
3c1oNAPEugenol synthase/0.462
3ibqATPPyridoxal kinase/0.462
3veu0GOBeta-secretase 13.4.23.460.462
4b1rITCTetracycline repressor protein class D/0.462
4dbc3QPAspartate aminotransferase2.6.1.10.462
4gutFADLysine-specific histone demethylase 1B10.462
1eiiRTLRetinol-binding protein 2/0.461
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.461
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.461
1w4lGL8Acetylcholinesterase3.1.1.70.461
1x1dSAHC-20 methyltransferase/0.461
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
2p5uNADUDP-glucose 4-epimerase/0.461
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.461
2uxoTACHTH-type transcriptional regulator TtgR/0.461
2viyVG3Beta-secretase 13.4.23.460.461
3b9lAZZSerum albumin/0.461
3fowIMHPurine nucleoside phosphorylase/0.461
3iktNADRedox-sensing transcriptional repressor Rex/0.461
3zkyWT4Isopenicillin N synthase1.21.3.10.461
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.461
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.461
1mczRMNBenzoylformate decarboxylase4.1.1.70.460
1odjGMPPurine nucleoside phosphorylase/0.460
1vi2NADQuinate/shikimate dehydrogenase/0.460
2ckmAA7Acetylcholinesterase3.1.1.70.460
2geuCOKPantothenate kinase2.7.1.330.460
2v16C47Renin3.4.23.150.460
2xuhTZ4Acetylcholinesterase3.1.1.70.460
2yoj8Y6Genome polyprotein2.7.7.480.460
3eon341Glutaryl-CoA dehydrogenase/0.460
4c72TLG3-oxoacyl-ACP synthase/0.460
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.460
4j7hTRHPCZA361.3/0.460
4q0kGA3Phytohormone-binding protein/0.460
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.460
4xbjIN5Alanine racemase, biosynthetic/0.460
5d6lCAUBeta-2 adrenergic receptor/0.460
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.459
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.459
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
2ct8MSPMethionine--tRNA ligase6.1.1.100.459
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.459
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.459
2vbpVB1Isopenicillin N synthase1.21.3.10.459
2xveFADPutative flavin-containing monooxygenase/0.459
3fr4F8AFatty acid-binding protein, adipocyte/0.459
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.459
3gnvXNZGenome polyprotein2.7.7.480.459
3gwfNAPCyclohexanone monooxygenase/0.459
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.459
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.459
4s1iPLPPyridoxal kinase, putative/0.459
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.459
1acjTHAAcetylcholinesterase3.1.1.70.458
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.458
1cnfFADNitrate reductase [NADH]1.7.1.10.458
1ex75GPGuanylate kinase2.7.4.80.458
1gc5ADPADP-dependent glucokinase2.7.1.1470.458
1tl7FOKAdenylate cyclase type 2/0.458
1tl7FOKAdenylate cyclase type 5/0.458
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.458
1vkgCRIHistone deacetylase 83.5.1.980.458
1zgbA1EAcetylcholinesterase3.1.1.70.458
2dvlFADAcyl-CoA dehydrogenase/0.458
2jl1NAPTriphenylmethane reductase/0.458
2oz57XYUncharacterized protein/0.458
2rlcCHDCholoylglycine hydrolase3.5.1.240.458
2x93X93Angiotensin-converting enzyme3.4.15.10.458
3af0GDPPantothenate kinase2.7.1.330.458
3bi5FADPolyamine oxidase FMS1/0.458
3cid318Beta-secretase 13.4.23.460.458
3hk1B64Fatty acid-binding protein, adipocyte/0.458
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
3p67FMNPentaerythritol tetranitrate reductase/0.458
3sff0DIHistone deacetylase 83.5.1.980.458
3t94MTAS-methyl-5'-thioadenosine phosphorylase/0.458
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.458
4bfwZVWPantothenate kinase2.7.1.330.458
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
4dpi0N1Beta-secretase 13.4.23.460.458
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.458
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.457
1nj5P5AProline--tRNA ligase/0.457
1rkwPNTHTH-type transcriptional regulator QacR/0.457
1vyrFMNPentaerythritol tetranitrate reductase/0.457
1x1aSAMC-20 methyltransferase/0.457
2g1n1IGRenin3.4.23.150.457
2g226IGRenin3.4.23.150.457
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.457
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.457
2v59LZKBiotin carboxylase6.3.4.140.457
2zbaZBATrichothecene 3-O-acetyltransferase/0.457
3f8wADNPurine nucleoside phosphorylase/0.457
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.457
3qwbNDPProbable quinone oxidoreductase1.6.5.50.457
3r95ACOMccE protein/0.457
3r96ACOMccE protein/0.457
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.457
4a6rTA8Probable aminotransferase/0.457
4fqsLYAThymidylate synthase ThyA/0.457
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.457
4lzwTHMUridine phosphorylase/0.457
4r81FMNPredicted NADH dehydrogenase/0.457
1gky5GPGuanylate kinase2.7.4.80.456
1gpuTHDTransketolase 12.2.1.10.456
1ngsTPPTransketolase 12.2.1.10.456
1nhkCMPNucleoside diphosphate kinase2.7.4.60.456
1q23FUAChloramphenicol acetyltransferase2.3.1.280.456
1qiqACCIsopenicillin N synthase1.21.3.10.456
1qoqIGPTryptophan synthase alpha chain/0.456
1qtiGNTAcetylcholinesterase3.1.1.70.456
1towCRZFatty acid-binding protein, adipocyte/0.456
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
2g1s4IGRenin3.4.23.150.456
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.456
2il2LIXRenin3.4.23.150.456
2iyfERYOleandomycin glycosyltransferase2.4.10.456
2jgsBTNAvidin/0.456
2kceD16Thymidylate synthase/0.456
2lfoGCHFatty acid-binding protein, liver/0.456
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.456
2xlpFADPutative flavin-containing monooxygenase/0.456
2xuiTZ5Acetylcholinesterase3.1.1.70.456
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
4bb3KKAIsopenicillin N synthase1.21.3.10.456
4g3jVNTLanosterol 14-alpha-demethylase/0.456
4jlm1NNDeoxycytidine kinase2.7.1.740.456
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.456
4nv1TYDFormyl transferase/0.456
4tl8AGSCircadian clock protein kinase KaiC2.7.11.10.456
4w5kPLPAspartate aminotransferase, mitochondrial/0.456
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
1bwlFMNNADPH dehydrogenase 11.6.99.10.455
1eveE20Acetylcholinesterase3.1.1.70.455
1l0oADPAnti-sigma F factor/0.455
1mrkFMCRibosome-inactivating protein alpha-trichosanthin3.2.2.220.455
1rftPXMPyridoxal kinase2.7.1.350.455
1xtrGNPGTP-binding protein Rheb/0.455
2abbFMNPentaerythritol tetranitrate reductase/0.455
2bktRPFRenin3.4.23.150.455
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3c35KAIGlutamate receptor ionotropic, kainate 1/0.455
3cic316Beta-secretase 13.4.23.460.455
3h06VBPGlutamate receptor 2/0.455
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.455
3icpNADNAD-dependent epimerase/dehydratase/0.455
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3pd2A3SThreonine--tRNA ligase6.1.1.30.455
4bftZVTPantothenate kinase2.7.1.330.455
4drkI63Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.455
4imfSI3N-acetylneuraminate lyase/0.455
4to5DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.455
4tyqAP5Adenylate kinase/0.455
1aqv0HGGlutathione S-transferase P2.5.1.180.454
1bsvNDPGDP-L-fucose synthase/0.454
1c7oPPGHemolysin/0.454
1cq6PY4Aspartate aminotransferase2.6.1.10.454
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.454
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.454
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
1pd9CO4Dihydrofolate reductase1.5.1.30.454
1q45FMN12-oxophytodienoate reductase 31.3.1.420.454
1rneC60Renin3.4.23.150.454
1s3uTQDDihydrofolate reductase1.5.1.30.454
1u08PLPMethionine aminotransferase/0.454
1u65CP0Acetylcholinesterase3.1.1.70.454
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.454
2hr8SAHDiphthine synthase/0.454
2nnqT4BFatty acid-binding protein, adipocyte/0.454
2r5nTPPTransketolase 1/0.454
2yj4ATPCopper-transporting ATPase/0.454
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.454
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.454
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.454
3o76GTBGlutathione S-transferase P 12.5.1.180.454
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.454
3pldF90Endothiapepsin3.4.23.220.454
3zeiAWHO-acetylserine sulfhydrylase/0.454
4d89BXDBeta-secretase 13.4.23.460.454
4i0h1BLBeta-secretase 13.4.23.460.454
4phlPILPhosphodiesterase/0.454
4psbGA3Cytokinin-specific binding protein/0.454
4q4kFMNUncharacterized protein/0.454
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.454
1icpFMN12-oxophytodienoate reductase 11.3.1.420.453
1touB1VFatty acid-binding protein, adipocyte/0.453
1u1cBAUUridine phosphorylase2.4.2.30.453
1u1gBBBUridine phosphorylase2.4.2.30.453
1udaUFGUDP-glucose 4-epimerase5.1.3.20.453
1xe65FPPlasmepsin-23.4.23.390.453
1xvvCCQL-carnitine CoA-transferase/0.453
2e07SAHDiphthine synthase/0.453
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.453
2g1r3IGRenin3.4.23.150.453
2ggbU17Methionine aminopeptidase/0.453
2gywOBIAcetylcholinesterase3.1.1.70.453
2oegUPGUDP-glucose pyrophosphorylase/0.453
2w6zL21Biotin carboxylase6.3.4.140.453
2y3sTIRTamL/0.453
2zgb21UProthrombin3.4.21.50.453
2zshGA3Gibberellin receptor GID1A30.453
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.453
3gkaFMNN-ethylmaleimide reductase/0.453
3lpkZ76Beta-secretase 13.4.23.460.453
3lqfNADGalactitol dehydrogenase/0.453
4dro0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.453
4fm80UQBeta-secretase 13.4.23.460.453
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.453
4ykfFADAlkyl hydroperoxide reductase subunit F1.8.10.453
5c1mCLRMu-type opioid receptor/0.453
3sn6P0GBeta-2 adrenergic receptor/0.453
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.452
1gpnHUBAcetylcholinesterase3.1.1.70.452
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
1r5gAO1Methionine aminopeptidase 2/0.452
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.452
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.452
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
2eeqSAHDiphthine synthase/0.452
2fj1CTCTetracycline repressor protein class D/0.452
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
2w6pOA4Biotin carboxylase6.3.4.140.452
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.452
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.452
3h3t16HCollagen type IV alpha-3-binding protein/0.452
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.452
3lqsPSZD-alanine aminotransferase2.6.1.210.452
3nxqRX4Angiotensin-converting enzyme3.2.10.452
3qbjNXZDipeptidyl peptidase 4/0.452
3sfh1DIHistone deacetylase 83.5.1.980.452
3ziuLSSLeucyl-tRNA synthetase/0.452
4acuQN7Beta-secretase 13.4.23.460.452
4bis8HQLysine-specific demethylase 4A1.14.110.452
4ggzBTNBll1558 protein/0.452
4l1xNAPAldo-keto reductase family 1 member C2/0.452
4rp8ASCAscorbate-specific PTS system EIIC component/0.452
6stdMS2Scytalone dehydratase4.2.1.940.452
1gtrATPGlutamine--tRNA ligase6.1.1.180.451
1pq944BOxysterols receptor LXR-beta/0.451
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.451
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.451
1x28PGUAspartate aminotransferase2.6.1.10.451
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.451
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.451
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.451
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.451
2v58LZJBiotin carboxylase6.3.4.140.451
2watCOAFatty acid synthase subunit alpha2.3.1.860.451
2wzwNDPNitroreductase NfnB/0.451
3bi2FADPolyamine oxidase FMS1/0.451
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
3go4SAHUncharacterized protein/0.451
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.451
3pkeY10Methionine aminopeptidase 2/0.451
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.451
3rimTPPTransketolase2.2.1.10.451
3rvhHQ2Lysine-specific demethylase 4A1.14.110.451
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.451
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.451
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.451
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.451
4frkDWDBeta-secretase 13.4.23.460.451
4mvcCDCCholine-phosphate cytidylyltransferase A/0.451
4nieNBHNuclear receptor ROR-gamma/0.451
4y9lFADAcyl-CoA dehydrogenase family member 11/0.451
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.451
1by5GLY_GLY_GLY_AHO_AHO_AHO_FEFerrichrome-iron receptor/0.450
1dggNDPCatalase1.11.1.60.450
1gaxVAAValine--tRNA ligase6.1.1.90.450
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.450
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1thnADPAnti-sigma F factor/0.450
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2c3oTPPPyruvate synthase/0.450
2eldSAHDiphthine synthase/0.450
2ha6SCKAcetylcholinesterase3.1.1.70.450
2rqfJH3Hemolymph juvenile hormone binding protein/0.450
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.450
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.450
3mauEXTPutative sphingosine-1-phosphate lyase/0.450
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.450
3occDIHPurine nucleoside phosphorylase DeoD-type/0.450
3v0p4GWHisto-blood group ABO system transferase/0.450
3wagTYDGlycosyltransferase/0.450
4a802ANMajor pollen allergen Bet v 1-A/0.450
4bquCLRJapanin/0.450
4e32DWNMethyltransferase/0.450
4enhFVXCholesterol 24-hydroxylase/0.450
4ipw1G7Mycocyclosin synthase1.14.21.90.450
4k88HFGBifunctional glutamate/proline--tRNA ligase6.1.1.150.450
4tm1FDAKtzI/0.450
1ay0TPPTransketolase 12.2.1.10.449
1dx6GNTAcetylcholinesterase3.1.1.70.449
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.449
1lc3NADBiliverdin reductase A1.3.1.240.449
1m9hNAD2,5-diketo-D-gluconic acid reductase A1.1.1.3460.449
1n3sGTPGTP cyclohydrolase 13.5.4.160.449
1sweBTNStreptavidin/0.449
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.449
1tj1FADBifunctional protein PutA1.5.5.20.449
1ut6A8NAcetylcholinesterase3.1.1.70.449
1w6rGNTAcetylcholinesterase3.1.1.70.449
1x1cSAHC-20 methyltransferase/0.449
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.449
2abaSTRPentaerythritol tetranitrate reductase/0.449
2cmfF11Acetylcholinesterase3.1.1.70.449
2d29FADAcyl-CoA dehydrogenase/0.449
2emrSAHDiphthine synthase/0.449
2g1y5IGRenin3.4.23.150.449
2g247IGRenin3.4.23.150.449
2he5NDPAldo-keto reductase family 1 member C211.1.10.449
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.449
2x7hPFNProstaglandin reductase 310.449
2xugTZ4Acetylcholinesterase3.1.1.70.449
2z4w749Geranylgeranyl pyrophosphate synthase/0.449
2zdv37UProthrombin3.4.21.50.449
2zevB71Geranylgeranyl pyrophosphate synthase/0.449
2zi224UProthrombin3.4.21.50.449
3br3ETHTH-type transcriptional regulator QacR/0.449
3fr28CAFatty acid-binding protein, adipocyte/0.449
3g70A5TRenin3.4.23.150.449
3h3sH15Collagen type IV alpha-3-binding protein/0.449
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.449
3p84FMNPentaerythritol tetranitrate reductase/0.449
3qt62P0Mevalonate diphosphate decarboxylase/0.449
3tfyMET_LEU_GLY_PRON-alpha-acetyltransferase 502.3.10.449
4b4vL34Bifunctional protein FolD/0.449
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.449
4df2FMNNADPH dehydrogenase/0.449
4g95OAGDihydrofolate reductase1.5.1.30.449
4layI63Peptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.449
1ao8MTXDihydrofolate reductase1.5.1.30.448
1bwsNDPGDP-L-fucose synthase/0.448
1dnpMHFDeoxyribodipyrimidine photo-lyase4.1.99.30.448
1el4CTZObelin/0.448
1hb3SCVIsopenicillin N synthase1.21.3.10.448
1mrqSTRAldo-keto reductase family 1 member C1/0.448
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.448
1tj2FADBifunctional protein PutA1.5.5.20.448
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2bp1NDPAflatoxin B1 aldehyde reductase member 2/0.448
2bqzSAHN-lysine methyltransferase KMT5A/0.448
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
2vyxFMNDodecin/0.448
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
3atyFMNProstaglandin F2a synthase/0.448
3in6FMNUncharacterized protein/0.448
3p8iFMNPentaerythritol tetranitrate reductase/0.448
3qviK95HAP protein/0.448
3rbaCODPhosphopantetheine adenylyltransferase/0.448
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.448
4ao4PLKBeta-transaminase/0.448
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.448
4gd40WSLysine-specific demethylase 4A1.14.110.448
4l5aTBNS-methyl-5'-thioadenosine phosphorylase/0.448
4xoqF42Coenzyme F420:L-glutamate ligase/0.448
1akaPLPAspartate aminotransferase, mitochondrial2.6.1.10.447
1dghNDPCatalase1.11.1.60.447
1h62ANBPentaerythritol tetranitrate reductase/0.447
1lpcCMPAntiviral protein DAP-303.2.2.220.447
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.447
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.447
2b56UTPRNA editing complex protein MP57/0.447
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.447
2jn3JN3Fatty acid-binding protein, liver/0.447
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.447
2zcvNDPQuinone oxidoreductase 21.6.5.20.447
2zevIPEGeranylgeranyl pyrophosphate synthase/0.447
3ag6PAJPantothenate synthetase/0.447
3apwDP0Alpha-1-acid glycoprotein 2/0.447
3c3xNAPEugenol synthase 11.1.1.3180.447
3fp0FP015-O-acetyltransferase/0.447
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.447
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
3tjlFMNNADPH dehydrogenase/0.447
3w3nRX8Toll-like receptor 8/0.447
4a7b3W5Collagenase 33.4.240.447
4aoaIK2Beta-phenylalanine transaminase2.6.10.447
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.447
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.447
4fkzUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.447
4fweFADLysine-specific histone demethylase 1B10.447
4hxyNDPPlm1/0.447
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.447
4mlp2CXCryptochrome-2/0.447
4n4v2GYTankyrase-12.4.2.300.447
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.447
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.447
4xymCOAAcyl-CoA synthetase (NDP forming)/0.447
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.447
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.447
8catNDPCatalase1.11.1.60.447
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.446
1dhfFOLDihydrofolate reductase1.5.1.30.446
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.446
1xs7MMIBeta-secretase 13.4.23.460.446
2h4k509Tyrosine-protein phosphatase non-receptor type 13.1.3.480.446
2j08IRFDeoxyribodipyrimidine photo-lyase4.1.99.30.446
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
2tplHPPTyrosine phenol-lyase4.1.99.20.446
2uxpCLMHTH-type transcriptional regulator TtgR/0.446
2vrbNAPTriphenylmethane reductase/0.446
2x91LPRAngiotensin-converting enzyme3.4.15.10.446
2xw19NVSerum albumin/0.446
2zi63D1Deoxycytidine kinase2.7.1.740.446
3djjFADGlutathione reductase, mitochondrial1.8.1.70.446
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3jziJZLBiotin carboxylase6.3.4.140.446
3pqbVGPPutative oxidoreductase/0.446
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.446
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.446
3zxzKRWHepatocyte growth factor receptor2.7.10.10.446
4a862ANMajor pollen allergen Bet v 1-A/0.446
4b66NAPL-ornithine N(5)-monooxygenase/0.446
4bb2STRCorticosteroid-binding globulin/0.446
4ca63EFAngiotensin-converting enzyme3.2.10.446
4lxa1YSBeta-secretase 13.4.23.460.446
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.446
4tlbAGSCircadian clock protein kinase KaiC2.7.11.10.446
4uy6SAHHistidine N-alpha-methyltransferase/0.446
4wasCOOEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.446
4y3jHICEndothiapepsin3.4.23.220.446
5fsi8DG7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.446
1bwkFMNNADPH dehydrogenase 11.6.99.10.445
1lv89PPPurine nucleoside phosphorylase2.4.2.10.445
1pl1ABYGlutathione S-transferase A12.5.1.180.445
1umaIN2Prothrombin3.4.21.50.445
1w76GNTAcetylcholinesterase3.1.1.70.445
1xddAAYIntegrin alpha-L/0.445
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.445
2dhfDZFDihydrofolate reductase1.5.1.30.445
2flhZEACytokinin-specific binding protein/0.445
2pdaTPPPyruvate synthase/0.445
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.445
2vijC44Beta-secretase 13.4.23.460.445
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.445
3drcMTXDihydrofolate reductase1.5.1.30.445
3ig6438Urokinase-type plasminogen activator3.4.21.730.445
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.445
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.445
3ojwFMNNADPH--cytochrome P450 reductase/0.445
3pi53P5Beta-secretase 13.4.23.460.445
3qbhQBHBeta-secretase 13.4.23.460.445
3qe2FMNNADPH--cytochrome P450 reductase/0.445
4dldTZGGlutamate receptor ionotropic, kainate 1/0.445
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.445
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.445
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.445
4ia7BIVVitamin D3 receptor A/0.445
4j0v1H7Beta-secretase 13.4.23.460.445
4n3l2FNProthrombin3.4.21.50.445
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.445
4qa2SHHHistone deacetylase 83.5.1.980.445
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.445
1b2lNDCAlcohol dehydrogenase1.1.1.10.444
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.444
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.444
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.444
1me6IVSPlasmepsin-23.4.23.390.444
1oc1ASVIsopenicillin N synthase1.21.3.10.444
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.444
1yqy915Lethal factor3.4.24.830.444
1yw7A41Methionine aminopeptidase 2/0.444
2b51UTPRNA editing complex protein MP57/0.444
2hdjNDPAldo-keto reductase family 1 member C2/0.444
2hm1LIQBeta-secretase 13.4.23.460.444
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.444
2ok8FADFerredoxin--NADP reductase, apicoplast/0.444
2v9cMREFMN-dependent NADH-azoreductase 1/0.444
2wezZYEBeta-secretase 13.4.23.460.444
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.444
3mauPLRPutative sphingosine-1-phosphate lyase/0.444
3mz9BHNNickel-binding periplasmic protein/0.444
3ndjJHZMethyltransferase/0.444
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3qvrFADGlucose oxidase1.1.3.40.444
3vsxR32Renin3.4.23.150.444
4krs1SXTankyrase-12.4.2.300.444
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.444
4qzuRTLRetinol-binding protein 2/0.444
4twnB96Ephrin type-A receptor 32.7.10.10.444
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.444
1beuIPLTryptophan synthase alpha chain/0.443
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.443
1f20FADNitric oxide synthase, brain1.14.13.390.443
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.443
1ftlDNQGlutamate receptor 2/0.443
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.443
1g63FMNEpidermin decarboxylase4.1.10.443
1h35R01Squalene--hopene cyclase4.2.1.1290.443
1icqFMN12-oxophytodienoate reductase 11.3.1.420.443
1jdvADNPurine nucleoside phosphorylase/0.443
1lkeDOGBilin-binding protein/0.443
1mxfMTXPutative pteridine reductase 2/0.443
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.443
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1ty8ADPProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.443
1wsbFMNFlavodoxin/0.443
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2a8yMTAS-methyl-5'-thioadenosine phosphorylase/0.443
2bgsNDPAldose reductase1.1.1.210.443
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.443
2e7rSAHDiphthine synthase/0.443
2ea2F77Methionine aminopeptidase 2/0.443
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.443
2ntrL00Beta-secretase 13.4.23.460.443
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.443
2pnuENMAndrogen receptor/0.443
2rhgIGPTryptophan synthase alpha chain/0.443
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.443
3e6eDCSAlanine racemase/0.443
3jpuTY4Transcriptional activator protein LasR/0.443
3lbeCOAUncharacterized protein/0.443
3nn6HNK6-hydroxy-L-nicotine oxidase/0.443
3to3ATPPetrobactin biosynthesis protein AsbB/0.443
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.443
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.443
4b64NAPL-ornithine N(5)-monooxygenase/0.443
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.443
4drm0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.443
4e31JHZMethyltransferase/0.443
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.443
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.443
4kxjP34Nucleoprotein/0.443
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.443
4zlaBESCytosol aminopeptidase3.4.11.10.443
4zp0DXCMultidrug transporter MdfA/0.443
1aiqCB3Thymidylate synthase/0.442
1dgfNDPCatalase1.11.1.60.442
1diuBDMDihydrofolate reductase1.5.1.30.442
1ek5NADUDP-glucose 4-epimerase/0.442
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.442
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.442
1gj5130Prothrombin3.4.21.50.442
1h63FMNPentaerythritol tetranitrate reductase/0.442
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
2dzbHH2Dihydropteroate synthase/0.442
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.442
2emuSAHDiphthine synthase/0.442
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.442
2ifaFMNUncharacterized protein/0.442
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.442
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.442
2o3uNGDADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.442
2o8jSAHHistone-lysine N-methyltransferase EHMT2/0.442
2vnnCM7Beta-secretase 13.4.23.460.442
2wmdZZ0NmrA-like family domain-containing protein 1/0.442
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.442
3e23SAMUncharacterized protein/0.442
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.442
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.442
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.442
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.442
3mjeNDPAmphB/0.442
3nx2FERFerulic acid decarboxylase/0.442
3q3cNADNAD-dependent L-serine dehydrogenase/0.442
3q43D66M1 family aminopeptidase3.4.110.442
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3vhmNPKAvidin/0.442
4b68FADL-ornithine N(5)-monooxygenase/0.442
4d965PAD-cysteine desulfhydrase/0.442
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.442
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.442
4nv0MG77-methylguanosine phosphate-specific 5'-nucleotidase/0.442
4qaiFMNNADPH dehydrogenase/0.442
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.300.442
4relKMPGlycosyltransferase/0.442
5choFADFlavin reductase/0.442
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.442
2rh1CAUBeta-2 adrenergic receptor/0.442
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.441
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.441
1h74AGSHomoserine kinase2.7.1.390.441
1i7mCGS-adenosylmethionine decarboxylase proenzyme4.1.1.500.441
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1mvsDTMDihydrofolate reductase1.5.1.30.441
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.441
1qy2IPZMajor urinary protein 1/0.441
1szgFNSCytochrome b2, mitochondrial1.1.2.30.441
1t7o152Carnitine O-acetyltransferase2.3.1.70.441
1w06W05Isopenicillin N synthase1.21.3.10.441
1xurPB5Collagenase 33.4.240.441
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.441
2a2sGSNGlutathione S-transferase P2.5.1.180.441
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.441
2dshSAHDiphthine synthase/0.441
2e0nSAHPrecorrin-2 C20-methyltransferase/0.441
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.441
2fb35ADGTP 3',8-cyclase4.1.99.180.441
2ga2A19Methionine aminopeptidase 2/0.441
2h94FADLysine-specific histone demethylase 1A10.441
2iko7IGRenin3.4.23.150.441
2on6IMHPurine nucleoside phosphorylase2.4.2.10.441
2p6lSAHDiphthine synthase/0.441
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.441
2qboCAMCamphor 5-monooxygenase1.14.15.10.441
2rh9IGPTryptophan synthase alpha chain/0.441
2stdCRPScytalone dehydratase4.2.1.940.441
2w6qOA5Biotin carboxylase6.3.4.140.441
2x7tWZBCarbonic anhydrase 24.2.1.10.441
2xlrFADPutative flavin-containing monooxygenase/0.441
2xvq9DSSerum albumin/0.441
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.441
3a0tADPSensor histidine kinase/0.441
3bi6396Wee1-like protein kinase2.7.10.20.441
3g0cRUFDipeptidyl peptidase 4/0.441
3g6zA7TRenin3.4.23.150.441
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3nh8DC2N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)3.5.1.1140.441
3pgtGBXGlutathione S-transferase P2.5.1.180.441
3tk3CPZCytochrome P450 2B41.14.14.10.441
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4ap1NAPSteroid monooxygenase/0.441
4b63FADL-ornithine N(5)-monooxygenase/0.441
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.441
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.441
4nqgCZHMitrocomin/0.441
4nv10FXFormyl transferase/0.441
4p9dTMPDeoxycytidylate deaminase/0.441
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
4zowCLMMultidrug transporter MdfA/0.441
1az2NAPAldose reductase1.1.1.210.440
1c4uIH1Prothrombin3.4.21.50.440
1j8qFMNFlavodoxin/0.440
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.440
1kkq471Peroxisome proliferator-activated receptor alpha/0.440
1nm6L86Prothrombin3.4.21.50.440
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.440
1oklMNSCarbonic anhydrase 24.2.1.10.440
1pagFMPAntiviral protein I3.2.2.220.440
1tehNADAlcohol dehydrogenase class-31.1.1.10.440
1w6hTITPlasmepsin-23.4.23.390.440
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1xpqFADPolyamine oxidase FMS1/0.440
2avxHTFRegulatory protein SdiA/0.440
2bxqIMNSerum albumin/0.440
2futH1SHeparin and heparin-sulfate lyase/0.440
2gbyBRNHTH-type transcriptional regulator QacR/0.440
2gilGTPRas-related protein Rab-6A/0.440
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.440
2owuSAHDiphthine synthase/0.440
2p83MR0Beta-secretase 13.4.23.460.440
2qn3F55Glycogen phosphorylase, muscle form2.4.1.10.440
2xejOKDGlutamate carboxypeptidase 23.4.17.210.440
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3f7bAG5Carbonic anhydrase 44.2.1.10.440
3fazNOSPurine nucleoside phosphorylase/0.440
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.440
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.440
3l6jZ90Alr2278 protein/0.440
3nsh957Beta-secretase 13.4.23.460.440
3nt5NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.440
3r7kFDAProbable acyl CoA dehydrogenase/0.440
3udq09EBeta-secretase 13.4.23.460.440
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.440
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.440
4an4DUDPutative glycosyl transferase/0.440
4b67NAPL-ornithine N(5)-monooxygenase/0.440
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.440
4boeCLRJapanin/0.440
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.440
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.440
4fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.440
4fapARDSerine/threonine-protein kinase mTOR2.7.11.10.440
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.440
4i0i957Beta-secretase 13.4.23.460.440
4iarERM5-hydroxytryptamine receptor 1B/0.440
4irnFADAnaB/0.440
4jicFMNGTN Reductase/0.440
4tm4FDAKtzI/0.440
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.440