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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1b38ATPCyclin-dependent kinase 22.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1b38ATPCyclin-dependent kinase 22.7.11.221.000
1hckATPCyclin-dependent kinase 22.7.11.220.571
1w8cN69Cyclin-dependent kinase 22.7.11.220.507
1b39ATPCyclin-dependent kinase 22.7.11.220.504
1pxlCK4Cyclin-dependent kinase 22.7.11.220.474
2a4lRRCCyclin-dependent kinase 22.7.11.220.472
2c6o4SPCyclin-dependent kinase 22.7.11.220.468
3lfqA28Cyclin-dependent kinase 22.7.11.220.466
3r83Z14Cyclin-dependent kinase 22.7.11.220.463
1e1xNW1Cyclin-dependent kinase 22.7.11.220.458
3plsANPMacrophage-stimulating protein receptor2.7.10.10.455
2r3jSCJCyclin-dependent kinase 22.7.11.220.453
4fklCK2Cyclin-dependent kinase 22.7.11.220.453
2b52D42Cyclin-dependent kinase 22.7.11.220.452
3lfnA27Cyclin-dependent kinase 22.7.11.220.450
1qmzATPCyclin-dependent kinase 22.7.11.220.449
5cnnANPEpidermal growth factor receptor2.7.10.10.449
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.448
2c5yMTWCyclin-dependent kinase 22.7.11.220.445
1y91CT9Cyclin-dependent kinase 22.7.11.220.443
3rpo24ZCyclin-dependent kinase 22.7.11.220.442