Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1ay0 | TPP | Transketolase 1 | 2.2.1.1 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 1.000 | |
1tkb | N1T | Transketolase 1 | 2.2.1.1 | 0.594 | |
1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.574 | |
3upt | TPP | Transketolase | / | 0.546 | |
1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.542 | |
1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.530 | |
1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.523 | |
1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.520 | |
1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.498 | |
2r5n | TPP | Transketolase 1 | / | 0.493 | |
3lq4 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.490 | |
2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.487 | |
2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.485 | |
2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.478 | |
2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.478 | |
3rim | TPP | Transketolase | 2.2.1.1 | 0.454 | |
1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.446 | |
2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
4q71 | FAD | Bifunctional protein PutA | / | 0.440 |