Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ascNPLAspartate aminotransferase2.6.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1ascNPLAspartate aminotransferase2.6.1.11.000
1cq8PY6Aspartate aminotransferase2.6.1.10.606
3qpg3QPAspartate aminotransferase2.6.1.10.603
4dbc3QPAspartate aminotransferase2.6.1.10.581
1cq7PY5Aspartate aminotransferase2.6.1.10.567
1cq6PY4Aspartate aminotransferase2.6.1.10.548
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.546
1maqPGUAspartate aminotransferase, mitochondrial2.6.1.10.537
1ivrCBAAspartate aminotransferase, mitochondrial2.6.1.10.528
1mapKETAspartate aminotransferase, mitochondrial2.6.1.10.514
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.513
1argPPDAspartate aminotransferase2.6.1.10.504
1ahgTYR_PLPAspartate aminotransferase2.6.1.10.501
2getCOKPantothenate kinase2.7.1.330.490
3q44D50M1 family aminopeptidase3.4.110.489
1toiHCIAspartate aminotransferase2.6.1.10.484
3frkTQPQdtB/0.481
1arhPPDAspartate aminotransferase2.6.1.10.472
1eyyNAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.471
2gesCOKPantothenate kinase2.7.1.330.470
3q43D66M1 family aminopeptidase3.4.110.467
1x28PGUAspartate aminotransferase2.6.1.10.466
2zsaADPPantothenate kinase2.7.1.330.465
4bfxZVXPantothenate kinase2.7.1.330.463
3qiyQI1Botulinum neurotoxin type A3.4.24.690.460
3dr7GPDGDP-perosamine synthase/0.459
2geuCOKPantothenate kinase2.7.1.330.458
3aezGDPPantothenate kinase2.7.1.330.457
1i59ANPChemotaxis protein CheA2.7.13.30.456
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.456
1tojHCIAspartate aminotransferase2.6.1.10.455
2zsdCOAPantothenate kinase2.7.1.330.455
1touB1VFatty acid-binding protein, adipocyte/0.453
2ptfFMNUncharacterized protein MTH_863/0.453
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.453
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.452
3vx4ATPPutative ABC transporter, ATP-binding protein ComA/0.451
4ba5PXGProbable aminotransferase/0.451
1xmmM7Gm7GpppX diphosphatase3.6.1.590.448
2e94364Geranylgeranyl pyrophosphate synthase/0.448
4bfsZVSPantothenate kinase2.7.1.330.448
4s0vSUVOrexin receptor type 2/0.448
1xjqADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.447
2gevCOKPantothenate kinase2.7.1.330.447
4bftZVTPantothenate kinase2.7.1.330.447
3cow52HPantothenate synthetase6.3.2.10.446
4dyb0MHNucleoprotein/0.446
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.445
2ylrNAPPhenylacetone monooxygenase1.14.13.920.444
2eixFADNADH-cytochrome b5 reductase/0.443
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.443
1esmCOAPantothenate kinase2.7.1.330.442
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.442
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.442
3kmyD8YBeta-secretase 13.4.23.460.442
3s5wFADL-ornithine N(5)-monooxygenase/0.442
4bfzZVZPantothenate kinase2.7.1.330.442
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.441
3buzTADIota toxin component Ia/0.441
3c1oNAPEugenol synthase/0.441
3f3sNADLambda-crystallin homolog/0.441
3o9pMHIPeriplasmic murein peptide-binding protein/0.441
1lnmDTXBilin-binding protein/0.440
1x8lOXRRetinol dehydratase/0.440
3af1GDPPantothenate kinase2.7.1.330.440
3af2ACPPantothenate kinase2.7.1.330.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440