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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1akrFMNFlavodoxin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1akrFMNFlavodoxin/1.000
1azlFMNFlavodoxin/0.714
1akwFMNFlavodoxin/0.631
5fx2FMNFlavodoxin/0.562
1c7fFMNFlavodoxin/0.558
1bu5RBFFlavodoxin/0.536
3f90FMNFlavodoxin/0.532
3f6rFMNFlavodoxin/0.522
4y7cFMNNADPH--cytochrome P450 reductase/0.521
1fx1FMNFlavodoxin/0.512
3f6sFMNFlavodoxin/0.507
1j9gFMNFlavodoxin/0.504
3ojxFMNNADPH--cytochrome P450 reductase/0.499
4fx2FMNFlavodoxin/0.481
1wsbFMNFlavodoxin/0.477
5xraFMNCannabinoid receptor 1/0.471
1akuFMNFlavodoxin/0.469
1j8qFMNFlavodoxin/0.454
1j9zFMNNADPH--cytochrome P450 reductase/0.453
1xyyFMNFlavodoxin/0.451
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.448
3kaqFMNFlavodoxin/0.445
4li81XQTankyrase-12.4.2.300.441
3sn6P0GBeta-2 adrenergic receptor/0.441