scPDB - Distribution of Binding site Similarity values of 12gs entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
12gs	0HH	Glutathione S-transferase P	2.5.1.18

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
12gs	0HH	Glutathione S-transferase P	2.5.1.18	1.000
17gs	GTX	Glutathione S-transferase P	2.5.1.18	0.785
1gti	GTB	Glutathione S-transferase P 1	2.5.1.18	0.636
1pgt	GTX	Glutathione S-transferase P	2.5.1.18	0.628
3pgt	GBX	Glutathione S-transferase P	2.5.1.18	0.624
13gs	SAS	Glutathione S-transferase P	2.5.1.18	0.615
4pgt	GBX	Glutathione S-transferase P	2.5.1.18	0.605
2oa7	GTX	Glutathione S-transferase P 1	2.5.1.18	0.568
20gs	CBD	Glutathione S-transferase P	2.5.1.18	0.558
2glr	GTX	Glutathione S-transferase P 1	2.5.1.18	0.552
1aqx	GTD	Glutathione S-transferase P	2.5.1.18	0.537
1gss	LEE	Glutathione S-transferase P	2.5.1.18	0.533
2oad	GTB	Glutathione S-transferase P 1	2.5.1.18	0.530
9gss	GTX	Glutathione S-transferase P	2.5.1.18	0.528
2j9h	GTX	Glutathione S-transferase P	2.5.1.18	0.522
1tu8	GTX	Glutathione S-transferase 2	2.5.1.18	0.508
2a2s	GSN	Glutathione S-transferase P	2.5.1.18	0.480
2gst	GPS	Glutathione S-transferase Mu 1	2.5.1.18	0.456
3gus	N11	Glutathione S-transferase P	2.5.1.18	0.442