sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 1.484 | |
| 3sx2 | NAD | Uncharacterized protein | / | 1.112 | |
| 3tsc | NAD | Uncharacterized protein | / | 1.051 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 1.034 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 1.003 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.996 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.995 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.977 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.972 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.965 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.955 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.940 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.939 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.932 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.931 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.928 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.927 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.926 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.923 | |
| 1iy8 | NAD | Levodione reductase | / | 0.914 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.911 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.902 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.902 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.899 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.895 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.894 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.886 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.884 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.879 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.879 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.876 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.870 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.870 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.867 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.866 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.866 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.866 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.865 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.863 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.863 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.862 | |
| 4kwh | NAP | Reductase homolog | / | 0.862 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.855 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.855 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.854 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.853 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.853 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.852 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.852 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.852 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.849 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.843 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.843 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.841 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.840 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.837 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.836 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.836 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.835 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.835 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.834 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.833 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.828 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.828 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.828 | |
| 3mje | NDP | AmphB | / | 0.826 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.826 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.826 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.824 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.823 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.822 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.822 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.821 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.820 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.817 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.814 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.812 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.811 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.811 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.809 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.808 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.805 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.802 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.801 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.800 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.799 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.796 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.794 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.794 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.792 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.787 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.787 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.786 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.784 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.783 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.782 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.782 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.781 | |
| 4qec | NAP | ElxO | / | 0.780 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.779 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.778 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.778 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.777 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.776 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.775 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.775 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.773 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.772 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.772 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.771 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.770 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.769 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.768 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.767 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.766 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.766 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.766 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.765 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.762 | |
| 3sju | NDP | Keto reductase | / | 0.761 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.760 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.757 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.755 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.754 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.753 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.752 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.751 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.751 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.750 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.748 | |
| 4qed | NAP | ElxO | / | 0.748 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.746 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.743 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.743 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.741 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.741 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.740 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.739 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.738 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.738 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.738 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.738 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.737 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.736 | |
| 4u7w | NDP | MxaA | / | 0.736 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.735 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.734 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.734 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.731 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.731 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.731 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.729 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.728 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.728 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.727 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.726 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.726 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.725 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.724 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.723 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.722 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.722 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.720 | |
| 4clo | NAP | Pteridine reductase | / | 0.719 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.717 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.716 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.716 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.715 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.715 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.714 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.713 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.712 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.711 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.711 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.711 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.710 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.710 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.709 | |
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 0.709 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.708 | |
| 3uce | NDP | Dehydrogenase | / | 0.708 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.706 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.706 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.705 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.703 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.703 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.702 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.702 | |
| 1sny | NAP | LD36273p | / | 0.701 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.701 | |
| 4hxy | NDP | Plm1 | / | 0.701 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.700 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.700 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.699 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.699 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.696 | |
| 4tm3 | FAD | KtzI | / | 0.695 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.694 | |
| 1sqf | SAM | Ribosomal RNA small subunit methyltransferase B | 2.1.1.176 | 0.692 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.692 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.691 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.691 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.691 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.690 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.689 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.689 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.689 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.689 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.688 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.688 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.687 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.685 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.684 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.684 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.684 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.684 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.683 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.683 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.683 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.682 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.682 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.682 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.680 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.680 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.679 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.678 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.678 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.677 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.676 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.676 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.676 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.676 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.675 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.675 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.674 | |
| 1ht0 | NAD | Alcohol dehydrogenase 1C | 1.1.1.1 | 0.673 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.673 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.672 | |
| 1p1h | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.671 | |
| 3pqf | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.671 | |
| 1i36 | NAP | Conserved protein | / | 0.669 | |
| 2nad | NAD | Formate dehydrogenase | / | 0.669 | |
| 2zth | SAM | Catechol O-methyltransferase | 2.1.1.6 | 0.669 | |
| 3bmo | NAP | Pteridine reductase | / | 0.669 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.669 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.668 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.668 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.667 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.667 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.667 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.667 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.667 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.667 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.667 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.667 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.665 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.665 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.664 | |
| 1xcb | NAD | Redox-sensing transcriptional repressor Rex | / | 0.664 | |
| 2ohx | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.664 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.664 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.664 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.664 | |
| 4y9d | NAI | C alpha-dehydrogenase | / | 0.664 | |
| 2np7 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.663 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.663 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.662 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.662 | |
| 3nt2 | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.662 | |
| 3uj8 | SFG | Phosphoethanolamine N-methyltransferase | / | 0.662 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.662 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.661 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.661 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.661 | |
| 4xb2 | NDP | 319aa long hypothetical homoserine dehydrogenase | / | 0.661 | |
| 5kjf | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.661 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.660 | |
| 3ou6 | SAM | SAM-dependent methyltransferase | / | 0.660 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.660 | |
| 3wv8 | ATP | Hmd co-occurring protein HcgE | / | 0.660 | |
| 4okn | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.659 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.659 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.658 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.658 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.657 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.657 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.657 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.656 | |
| 1y7t | NDP | Malate dehydrogenase | / | 0.656 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.656 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.656 | |
| 1hyh | NAD | L-2-hydroxyisocaproate dehydrogenase | / | 0.655 | |
| 1lde | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.655 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.655 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.655 | |
| 4jk3 | NAD | Uncharacterized protein | / | 0.655 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.655 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.654 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.654 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.654 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.654 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.654 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.654 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.653 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.652 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.652 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.652 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.652 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.652 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.651 | |
| 2nyu | SAM | rRNA methyltransferase 2, mitochondrial | / | 0.651 | |
| 3l4s | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.651 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.651 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.651 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.650 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.650 | |
| 4ek9 | EP4 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.650 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.650 |