Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5dac AGS Uncharacterized protein

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
5dac AGSUncharacterized protein / 1.118
5da9 AGSUncharacterized protein / 0.896
3fvq ATPFe(3+) ions import ATP-binding protein FbpC / 0.791
1xef ATPAlpha-hemolysin translocation ATP-binding protein HlyB / 0.783
2py7 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.761
3vx4 ATPPutative ABC transporter, ATP-binding protein ComA / 0.759
4tle AGSCircadian clock protein kinase KaiC 2.7.11.1 0.754
4tl8 AGSCircadian clock protein kinase KaiC 2.7.11.1 0.752
4tla ADPCircadian clock protein kinase KaiC 2.7.11.1 0.752
3w3z GTPGTP-binding nuclear protein Ran / 0.742
2bku GTPGTP-binding nuclear protein Ran / 0.741
3vhx GTPADP-ribosylation factor 6 / 0.741
4tlc AGSCircadian clock protein kinase KaiC 2.7.11.1 0.741
4tlb AGSCircadian clock protein kinase KaiC 2.7.11.1 0.737
4qm6 GTPMetallophosphoesterase / 0.735
4tld AGSCircadian clock protein kinase KaiC 2.7.11.1 0.735
3m0e ATPTranscriptional regulator (NtrC family) / 0.732
4ki0 ANPMaltose/maltodextrin import ATP-binding protein MalK / 0.732
3wyf GTPGTP-binding nuclear protein / 0.728
1aq2 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.727
1k5d GNPGTP-binding nuclear protein Ran / 0.723
1ytm ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.723
4tl9 AGSCircadian clock protein kinase KaiC 2.7.11.1 0.722
1gia GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.721
1tu3 GNPRas-related protein Rab-5A / 0.720
1w1w AGSStructural maintenance of chromosomes protein 1 / 0.720
4pao GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.719
4tl6 ANPCircadian clock protein kinase KaiC 2.7.11.1 0.715
1gwn GTPRho-related GTP-binding protein RhoE / 0.713
1t91 GTPRas-related protein Rab-7a / 0.711
2jj2 ADPATP synthase subunit alpha, mitochondrial / 0.711
2jj2 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.711
4mkf AP5Adenylate kinase / 0.711
1wa5 GTPGTP-binding nuclear protein Ran / 0.710
4r9u ANPVitamin B12 import ATP-binding protein BtuD / 0.710
1cs4 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.709
1e96 GTPRas-related C3 botulinum toxin substrate 1 / 0.709
1svm ATPLarge T antigen 3.6.4 0.708
2rgx AP5Adenylate kinase / 0.708
2c5l GTPGTPase HRas / 0.706
1sdm ADPKinesin heavy chain-like protein / 0.705
3law GNPRas-related protein Rab-7a / 0.704
1l2t ATPUncharacterized ABC transporter ATP-binding protein MJ0796 / 0.703
2gvd GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.703
1gil GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.702
2v7q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.702
3cx8 GSPGuanine nucleotide-binding protein subunit alpha-13 / 0.699
3pfi ADPHolliday junction ATP-dependent DNA helicase RuvB / 0.699
4nu0 AP5Adenylate kinase / 0.698
4w5j AP5Adenylate kinase / 0.698
2zet GTPRas-related protein Rab-27B / 0.697
3hqd ANPKinesin-like protein KIF11 / 0.697
2olq ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.696
5c46 GSPRas-related protein Rab-11A / 0.696
2fju GSPRas-related C3 botulinum toxin substrate 1 / 0.695
4jsy GTPMetallophosphoesterase / 0.695
1mmg AGSMyosin-2 heavy chain / 0.694
4d0l GSPRas-related protein Rab-11A / 0.694
5jlj GNPGTP-binding nuclear protein Ran / 0.694
1p3j AP5Adenylate kinase / 0.693
3wyg GTPGTP-binding nuclear protein GSP1/CNR1 / 0.693
1n6l GTPRas-related protein Rab-5A / 0.692
3rs5 GNPGTPase HRas / 0.692
4kln AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.692
4mkg AP5Adenylate kinase / 0.692
5b2z GNPGTPase HRas / 0.692
3c41 ANPAmino acid ABC transporter / 0.691
3i3s GNPGTPase HRas / 0.691
1bof GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.690
1xp8 AGSProtein RecA / 0.690
4l9w GNPGTPase HRas / 0.690
1e1q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.689
1q3h ANPCystic fibrosis transmembrane conductance regulator / 0.689
4kvg GTPRas-related protein Rap-1A / 0.689
4pfp ADPUnconventional myosin-VI / 0.689
2rge GNPGTPase HRas / 0.687
2zfi ADPKinesin-like protein KIF1A / 0.687
4cym GCPRas-related protein Rab-32 / 0.687
2gil GTPRas-related protein Rab-6A / 0.686
3tkl GTPRas-related protein Rab-1A / 0.686
4dso GSPGTPase KRas / 0.686
4v02 ATPSite-determining protein / 0.686
2fgk ATPAlpha-hemolysin translocation ATP-binding protein HlyB / 0.685
2xau ADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 3.6.4.13 0.685
1xmv ADPProtein RecA / 0.684
4g0n GNPGTPase HRas / 0.684
4ol0 GTPGTP-binding nuclear protein Ran / 0.684
1svl ADPLarge T antigen 3.6.4 0.682
3k8y GNPGTPase HRas / 0.681
1r0z ATPCystic fibrosis transmembrane conductance regulator / 0.680
3dl0 AP5Adenylate kinase / 0.680
2uyi ADPKinesin-like protein KIF11 / 0.679
2y65 ADPKinesin heavy chain / 0.679
1m7b GTPRho-related GTP-binding protein RhoE / 0.678
1rj9 GCPSignal recognition particle receptor FtsY / 0.678
2xtz GSPGuanine nucleotide-binding protein alpha-1 subunit / 0.678
1zc3 GNPRas-related protein Ral-A / 0.677
2r9v ATPATP synthase subunit alpha / 0.677
3pcr GTPADP-ribosylation factor 6 / 0.677
1xts GTPGTP-binding protein Rheb / 0.676
3nbz GTPGTP-binding nuclear protein Ran / 0.676
3oiu GNPGTPase HRas / 0.676
3v4f GNPGTPase HRas / 0.676
5ftc ADPTPR domain protein / 0.676
1fmw ATPMyosin-2 heavy chain / 0.675
1wdt GTPElongation factor G (EF-G-2) / 0.675
2cls GTPRho-related GTP-binding protein Rho6 / 0.675
4dlv GNPGTPase HRas / 0.675
4ihq ADPConserved Archaeal protein / 0.675
4nyj GNPGTPase HRas / 0.675
3th5 GNPRas-related C3 botulinum toxin substrate 1 / 0.674
4ihj GTPTubulin alpha-1B chain / 0.674
4k81 GTPGTPase HRas / 0.674
4xsg GSPTransforming protein RhoA / 0.674
4hdo GNPRas-related protein Rap-1b / 0.673
1cul GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.672
4rkf GNPRas-related protein Rab-3 / 0.672
4k9o TPPBenzoylformate decarboxylase 4.1.1.7 0.671
4qxa GTPRas-related protein Rab-9A / 0.671
4tyq AP5Adenylate kinase / 0.671
1yzq GNPRas-related protein Rab-6A / 0.670
1z2a GDPRas-related protein Rab-23 / 0.670
2ffq GSPRas-related protein Rab-6B / 0.670
2jib TPPOxalyl-CoA decarboxylase 4.1.1.8 0.670
2oo7 AP5Adenylate kinase / 0.669
2gm1 ADPKinesin-like protein KIF11 / 0.668
2iut AGSDNA translocase FtsK / 0.668
4tl7 ATPCircadian clock protein kinase KaiC 2.7.11.1 0.668
3c14 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.667
3dt2 GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.667
3dt4 GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.667
3oiw GNPGTPase HRas / 0.667
3pit GNPRas-related protein M-Ras / 0.667
4a1z ADPKinesin-like protein KIF11 / 0.667
5di3 GNPADP-ribosylation factor-like protein 3 / 0.667
2j0v GDPRac-like GTP-binding protein ARAC7 / 0.666
2c31 TZDOxalyl-CoA decarboxylase 4.1.1.8 0.664
2fg5 GNPRas-related protein Rab-31 / 0.664
2hf8 GSPProbable hydrogenase nickel incorporation protein HypB / 0.664
2ji7 OXTOxalyl-CoA decarboxylase 4.1.1.8 0.664
2jj2 ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.664
3eg5 GNPCell division control protein 42 homolog / 0.664
3k0f ATPCircadian clock protein kinase KaiC 2.7.11.1 0.664
3zia ATPATP synthase subunit alpha, mitochondrial / 0.664
1kmq GNPTransforming protein RhoA / 0.663
1pow TPPPyruvate oxidase 1.2.3.3 0.663
2jiz ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.663
3mjh GTPRas-related protein Rab-5A / 0.663
4cei ANPATP-dependent helicase/deoxyribonuclease subunit B 3.1 0.663
2gcp GSPRho-related GTP-binding protein RhoC / 0.662
2qtv GNPSmall COPII coat GTPase SAR1 3.6.5 0.662
3rab GNPRas-related protein Rab-3A / 0.662
3rsl GNPGTPase HRas / 0.662
3t1t GDPProbable gliding protein mglA / 0.662
4dlw GNPGTPase HRas / 0.662
3l8y GNPGTPase HRas / 0.661
3rs0 GNPGTPase HRas / 0.661
4js0 GNPCell division control protein 42 homolog / 0.661
4xjx ATPType I restriction enzyme EcoR124II R protein 3.1.21.3 0.661
2osb AP5Adenylate kinase / 0.660
4o25 GTPGTP-binding protein Rheb / 0.660
4wbn GTPTubulin alpha-1B chain / 0.660
1u0h GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.659
2eu8 AP5Adenylate kinase / 0.659
3b1x GNPFerrous iron transport protein B / 0.659
1vg8 GNPRas-related protein Rab-7a / 0.658
3sbd GNPRas-related C3 botulinum toxin substrate 1 / 0.658
4khy TTPDNA-directed DNA polymerase / 0.658
5dha GNPGTP-binding nuclear protein Ran / 0.658
1w0k ADPATP synthase subunit alpha, mitochondrial / 0.657
1w0k ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.657
3a6p GTPGTP-binding nuclear protein Ran / 0.657
3cph GDPRas-related protein SEC4 / 0.657
3e5h GNPRas-related protein Rab-28 / 0.657
3oes GNPGTPase RhebL1 / 0.657
3x1z GNPRas-related protein Rap-1b / 0.657
4hut ATPCob(I)yrinic acid a,c-diamide adenosyltransferase 2.5.1.17 0.657
1y9d TPPPyruvate oxidase 1.2.3.3 0.656
3cf0 ADPTransitional endoplasmic reticulum ATPase 3.6.4.6 0.656
3oiv GNPGTPase HRas / 0.656
4nh0 ATPESX secretion system protein EccC / 0.656
1h8h ATPATP synthase subunit alpha, mitochondrial / 0.655
1h8h ATPATP synthase subunit beta, mitochondrial 3.6.3.14 0.655
1sxj AGSReplication factor C subunit 1 / 0.655
1zc4 GNPRas-related protein Ral-A / 0.655
2p2l GDPRas-related C3 botulinum toxin substrate 1 / 0.655
3cob ADPKinesin heavy chain-like protein / 0.655
4dzz ADPPlasmid partitioning protein ParF / 0.655
4ffb GTPTubulin alpha-1 chain / 0.655
4fvq ATPTyrosine-protein kinase JAK2 / 0.655
2g1q ADPKinesin-like protein KIF11 / 0.654
2j5x GSPADP-ribosylation factor 6 / 0.654
3krf DSTGeranyl diphosphate synthase large subunit / 0.654
3myk ANPMyosin-2 heavy chain / 0.654
4gvz ADPArginine kinase 2.7.3.3 0.654
4gzl GNPRas-related C3 botulinum toxin substrate 1 / 0.654
4zca ADPKinesin-like protein KIF11 / 0.653
1zio AP5Adenylate kinase / 0.652
2fna ADPUncharacterized protein / 0.652
2j7p GNPSignal recognition particle protein / 0.652
2j7p GNPSignal recognition particle receptor FtsY / 0.652
2xae ADPKinesin-like protein KIF11 / 0.652
3bc1 GNPRas-related protein Rab-27A / 0.652
3hu1 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.652
4g01 GDPRas-related protein RABF2b / 0.652
4qnr ATPPsp operon transcriptional activator / 0.652
5aun ADPIron-sulfur cluster carrier protein / 0.652
1zbd GTPRas-related protein Rab-3A / 0.651
2oap ANPType II secretion system protein (GspE-2) / 0.651
2olr ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.651
4lhw GNPRas-related protein Rab-8A / 0.651
1e1q ANPATP synthase subunit alpha, mitochondrial / 0.650
1e1q ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.650
1svw GTPProbable GTP-binding protein EngB / 0.650
2whx ADPGenome polyprotein 3.4.21.91 0.650
3bos CDPRegulatory inactivation of DnaA Hda protein / 0.650
3kko GNPRas-related protein M-Ras / 0.650
3mhy ATPNitrogen regulatory protein P-II 1 / 0.650
4l8g GDPGTPase KRas / 0.650