Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5d7q AR6 NAD-dependent protein deacetylase sirtuin-2 3.5.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
5d7q AR6NAD-dependent protein deacetylase sirtuin-2 3.5.1 1.301
5d7p AR6NAD-dependent protein deacetylase sirtuin-2 3.5.1 1.254
5d7o AR6NAD-dependent protein deacetylase sirtuin-2 3.5.1 1.175
4bvh AR6NAD-dependent protein deacetylase sirtuin-3, mitochondrial 3.5.1 1.077
2h59 3ODNAD-dependent protein deacetylase / 1.061
2h59 APRNAD-dependent protein deacetylase / 1.037
3zg6 APRNAD-dependent protein deacetylase sirtuin-6 3.5.1 1.034
4bvb AR6NAD-dependent protein deacetylase sirtuin-3, mitochondrial 3.5.1 1.027
1m2g APRNAD-dependent protein deacylase 1 / 0.961
1m2h APRNAD-dependent protein deacylase 1 / 0.957
1m2k APRNAD-dependent protein deacylase 1 / 0.935
1m2j APRNAD-dependent protein deacylase 1 / 0.856
1yc2 APRNAD-dependent protein deacylase 2 / 0.825
3d4b DZDNAD-dependent protein deacetylase / 0.824
2b4y APRNAD-dependent protein deacylase sirtuin-5, mitochondrial / 0.820
4iao APRNAD-dependent histone deacetylase SIR2 3.5.1 0.816
4zzj CNANAD-dependent protein deacetylase sirtuin-1 3.5.1 0.806
1s7g APRNAD-dependent protein deacylase 2 / 0.762
1szc CNANAD-dependent protein deacetylase HST2 3.5.1 0.742
3cls FADElectron transfer flavoprotein subunit alpha / 0.695
2qqf A1RNAD-dependent protein deacetylase HST2 3.5.1 0.687
1efp FADElectron transfer flavoprotein subunit alpha / 0.676
2dji FADPyruvate oxidase / 0.674
2q28 ADPOxalyl-CoA decarboxylase 4.1.1.8 0.652
3k7m FAD6-hydroxy-L-nicotine oxidase / 0.650
4d5g FADCyclohexane-1,2-dione hydrolase 3.7.1.11 0.650