Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5br7 FAD UDP-galactopyranose mutase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
5br7 FADUDP-galactopyranose mutase / 1.433
1v0j FADUDP-galactopyranose mutase 5.4.99.9 1.070
2yg5 FADPutrescine oxidase / 0.813
1f8r FADL-amino-acid oxidase 1.4.3.2 0.799
3rha FDAPutrescine oxidase / 0.794
3kyb FADUDP-galactopyranose mutase 5.4.99.9 0.792
2iid FADL-amino-acid oxidase 1.4.3.2 0.783
3int FDAUDP-galactopyranose mutase 5.4.99.9 0.772
4gde FDAUDP-galactopyranose mutase / 0.768
4u8k FDAUDP-galactopyranose mutase / 0.767
4rpg FADUDP-galactopyranose mutase 5.4.99.9 0.766
2yg7 FADPutrescine oxidase / 0.765
1wam FADUDP-galactopyranose mutase 5.4.99.9 0.763
4gut FADLysine-specific histone demethylase 1B 1 0.760
2yg6 FADPutrescine oxidase / 0.758
3nn6 FB06-hydroxy-L-nicotine oxidase / 0.758
2bi8 FADUDP-galactopyranose mutase 5.4.99.9 0.757
2yg3 FADPutrescine oxidase / 0.757
3hdy FDAUDP-galactopyranose mutase / 0.752
1i8t FADUDP-galactopyranose mutase 5.4.99.9 0.751
3utg FDAUDP-galactopyranose mutase / 0.751
4u8m FDAUDP-galactopyranose mutase / 0.751
3k7m FAD6-hydroxy-L-nicotine oxidase / 0.750
3ute FADUDP-galactopyranose mutase / 0.749
2bab FADPutative aminooxidase / 0.748
2c3c FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.748
4guu FA9Lysine-specific histone demethylase 1B 1 0.740
2yg4 FADPutrescine oxidase / 0.738
4u2s FDACholesterol oxidase 1.1.3.6 0.738
4u8i FDAUDP-galactopyranose mutase / 0.738
4u8n FDAUDP-galactopyranose mutase / 0.737
3qvr FADGlucose oxidase 1.1.3.4 0.735
4u8p FDAUDP-galactopyranose mutase / 0.734
2c7g FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.732
2eq7 FADDihydrolipoyl dehydrogenase / 0.730
4gdc FADUDP-galactopyranose mutase / 0.726
2cvj FADThioredoxin reductase related protein / 0.725
3uka FADUDP-galactopyranose mutase / 0.725
4gdd FADUDP-galactopyranose mutase / 0.724
4qi5 FADCellobiose dehydrogenase / 0.724
1get FADGlutathione reductase 1.8.1.7 0.723
2q7v FADThioredoxin reductase / 0.723
3cty FADProbable thioredoxin reductase / 0.723
3lov FADProtoporphyrinogen oxidase / 0.723
3gyj FADCholesterol oxidase 1.1.3.6 0.722
1h81 FADPolyamine oxidase 1.5.3.14 0.720
1rp0 AHZThiamine thiazole synthase, chloroplastic / 0.720
1lqu FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.718
3mj4 FADUDP-galactopyranose mutase / 0.717
5l3d FADLysine-specific histone demethylase 1A 1 0.717
4udq FAD5-(hydroxymethyl)furfural oxidase / 0.714
1e6e FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.713
3qj4 FADRenalase / 0.713
2gvc FADThiol-specific monooxygenase 1.14.13 0.712
4cy8 FDA2-hydroxybiphenyl-3-monooxygenase / 0.711
2ylz FADPhenylacetone monooxygenase 1.14.13.92 0.710
2hqm FADGlutathione reductase 1.8.1.7 0.709
2uxx FAJLysine-specific histone demethylase 1A 1 0.709
3ics FADCoenzyme A disulfide reductase / 0.709
3ka7 FADPutative oxidoreductase / 0.709
3uoz FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.707
3q9t FAYUncharacterized protein / 0.706
2b9x FADPutative aminooxidase / 0.705
5g3t FDAFlavin-dependent L-tryptophan oxidase VioA / 0.705
1w4x FADPhenylacetone monooxygenase 1.14.13.92 0.704
4rph FADUDP-galactopyranose mutase 5.4.99.9 0.704
2bi7 FADUDP-galactopyranose mutase 5.4.99.9 0.703
3atq FDAConserved Archaeal protein / 0.703
3ict FADCoenzyme A disulfide reductase / 0.703
3ish FADThioredoxin reductase 1.8.1.9 0.703
3ukl FADUDP-galactopyranose mutase / 0.703
4ech FADPolyamine oxidase FMS1 / 0.703
4mo2 FADUDP-galactopyranose mutase / 0.703
4qi4 FADCellobiose dehydrogenase / 0.703
3kve FADL-amino-acid oxidase / 0.702
3zdn FADMonoamine oxidase N 1.4.3.4 0.702
4wx1 FDAUDP-galactopyranose mutase / 0.702
3icr FADCoenzyme A disulfide reductase / 0.701
3ukf FDAUDP-galactopyranose mutase / 0.701
5j60 FADThioredoxin reductase / 0.701
2eq8 FADDihydrolipoyl dehydrogenase / 0.700
2gmh FADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial 1.5.5.1 0.700
2q0k FADThioredoxin reductase 1.8.1.9 0.700
2wow FADTrypanothione reductase / 0.700
2y48 FADLysine-specific histone demethylase 1A 1 0.699
3he3 FADUDP-galactopyranose mutase / 0.699
1h83 FADPolyamine oxidase 1.5.3.14 0.698
4mo2 FDAUDP-galactopyranose mutase / 0.698
4hsu FADLysine-specific histone demethylase 1B 1 0.697
1zmc FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.696
4aox FADSteroid monooxygenase / 0.696
4yac NAIC alpha-dehydrogenase / 0.696
2b9y FADPutative aminooxidase / 0.695
3gwd FADCyclohexanone monooxygenase / 0.695
1n4u FAECholesterol oxidase 1.1.3.6 0.694
3cge FADCoenzyme A disulfide reductase / 0.694
3cnj FADCholesterol oxidase 1.1.3.6 0.694
3gyi FADCholesterol oxidase 1.1.3.6 0.694
2ym1 FADPhenylacetone monooxygenase 1.14.13.92 0.693
4ap3 FADSteroid monooxygenase / 0.693
1e1k FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.692
1z6l FADPolyamine oxidase FMS1 / 0.692
2qa1 FADPgaE / 0.692
4qi7 FADCellobiose dehydrogenase / 0.691
1gpe FADGlucose oxidase 1.1.3.4 0.690
3s5w FADL-ornithine N(5)-monooxygenase / 0.690
5hhf FDAUDP-galactopyranose mutase / 0.690
5je2 SAHMethyl transferase / 0.690
4ocg FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.689
1grg FADGlutathione reductase, mitochondrial 1.8.1.7 0.688
2ylw FADPhenylacetone monooxygenase 1.14.13.92 0.688
2iw5 FADLysine-specific histone demethylase 1A 1 0.687
2ylx FADPhenylacetone monooxygenase 1.14.13.92 0.687
2yr4 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.687
3pl8 FADPyranose 2-oxidase / 0.687
1grb FADGlutathione reductase, mitochondrial 1.8.1.7 0.686
4udr FAD5-(hydroxymethyl)furfural oxidase / 0.686
1gsn FADGlutathione reductase, mitochondrial 1.8.1.7 0.685
2fje FADAdenylylsulfate reductase, subunit A (AprA) / 0.685
2yqu FADDihydrolipoyl dehydrogenase / 0.685
3bgv SAHmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.684
3djg FADGlutathione reductase, mitochondrial 1.8.1.7 0.684
3hdy FADUDP-galactopyranose mutase / 0.684
3epp SFGmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.683
3nlc FADUncharacterized protein / 0.683
4fn4 NADShort chain dehydrogenase / 0.683
2gew FADCholesterol oxidase 1.1.3.6 0.682
3g07 SAM7SK snRNA methylphosphate capping enzyme 2.1.1 0.682
3vqr FADPutative oxidoreductase / 0.682
4z24 FADPutative GMC-type oxidoreductase R135 1 0.682
1gre FADGlutathione reductase, mitochondrial 1.8.1.7 0.680
1jnr FADAdenylylsulfate reductase, subunit A (AprA) / 0.680
2ign FADPyranose 2-oxidase / 0.680
2tpr FADTrypanothione reductase 1.8.1.12 0.680
1cjc FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.679
2eq6 FADDihydrolipoyl dehydrogenase / 0.679
3grs FADGlutathione reductase, mitochondrial 1.8.1.7 0.679
1e1l FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.678
2f5z FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.678
2ylr FADPhenylacetone monooxygenase 1.14.13.92 0.678
4mih FADPyranose 2-oxidase 1.1.3.10 0.678
3sqp FADGlutathione reductase, mitochondrial 1.8.1.7 0.677
4ees FMNPhototropin-2 2.7.11.1 0.677
1grh FADGlutathione reductase, mitochondrial 1.8.1.7 0.676
1n4v FADCholesterol oxidase 1.1.3.6 0.676
1n4w FADCholesterol oxidase 1.1.3.6 0.676
2igo FADPyranose 2-oxidase / 0.676
4b69 FADL-ornithine N(5)-monooxygenase / 0.676
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.675
1rq1 FADEndoplasmic oxidoreductin-1 1.8.4 0.675
2ba9 FADPutative aminooxidase / 0.675
2dw4 FADLysine-specific histone demethylase 1A 1 0.675
3b6d FAECholesterol oxidase 1.1.3.6 0.675
4j57 FADThioredoxin reductase 2 1.8.1.9 0.675
1k4q FADGlutathione reductase, mitochondrial 1.8.1.7 0.674
2jae FADL-amino acid oxidase / 0.674
2ym2 FADPhenylacetone monooxygenase 1.14.13.92 0.674
3up5 FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.674
3cox FADCholesterol oxidase 1.1.3.6 0.673
3d72 FADVivid PAS protein VVD / 0.673
3urh FADDihydrolipoyl dehydrogenase / 0.672
4eet FMNPhototropin-2 2.7.11.1 0.672
4gur FADLysine-specific histone demethylase 1B 1 0.672
4xwr FADCholesterol oxidase 1.1.3.6 0.672
1n1p FADCholesterol oxidase 1.1.3.6 0.671
1zmd FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.671
3ukk FADUDP-galactopyranose mutase / 0.671
4opl FDAConserved Archaeal protein / 0.671
4tlz FADKtzI / 0.671
4xxg FADCholesterol oxidase 1.1.3.6 0.671
1ps9 FAD2,4-dienoyl-CoA reductase 1.3.1.34 0.670
5g3s FDAFlavin-dependent L-tryptophan oxidase VioA / 0.670
2yr5 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.669
3cgb FADCoenzyme A disulfide reductase / 0.669
3ukk FDAUDP-galactopyranose mutase / 0.669
3ab1 FADFerredoxin--NADP reductase 1.18.1.2 0.668
1geu FADGlutathione reductase 1.8.1.7 0.667
3dh9 FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.667
4cnk FADL-amino acid oxidase / 0.667
1d7l RFLp-hydroxybenzoate hydroxylase / 0.666
3cgc FADCoenzyme A disulfide reductase / 0.666
3oc4 FADOxidoreductase, pyridine nucleotide-disulfide family / 0.666
5je4 SAHMethyl transferase / 0.666
2vqb FADPutative flavin-containing monooxygenase / 0.665
3lsh FADPyranose 2-oxidase / 0.665
5djt FMNNPH1-2 / 0.665
1lpf FADDihydrolipoyl dehydrogenase 1.8.1.4 0.664
2b9w FADPutative aminooxidase / 0.664
4rek FADCholesterol oxidase 1.1.3.6 0.664
5cdt NAJAlcohol dehydrogenase E chain 1.1.1.1 0.664
2bry FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.663
3dgh FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.663
3r9u FADThioredoxin reductase / 0.663
3bi5 FADPolyamine oxidase FMS1 / 0.662
4jnq FDAThioredoxin reductase / 0.662
2gr3 FADFerredoxin reductase / 0.661
2jb2 FADL-amino acid oxidase / 0.661
2pv7 NADT-protein 1.3.1.12 0.661
4eqx FADCoenzyme A disulfide reductase / 0.661
4i58 FADCyclohexylamine Oxidase / 0.661
4eqw FADCoenzyme A disulfide reductase / 0.660
4ntd FADThioredoxin reductase / 0.660
2xvf FADPutative flavin-containing monooxygenase / 0.659
3lad FADDihydrolipoyl dehydrogenase / 0.659
3nt6 FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.659
4b66 FADL-ornithine N(5)-monooxygenase / 0.659
4em3 FADCoenzyme A disulfide reductase / 0.659
4fwe FADLysine-specific histone demethylase 1B 1 0.659
4lii FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.659
4mok FADPyranose 2-oxidase / 0.659
4nzh FADL-ornithine N(5)-monooxygenase / 0.659
4xbf FADLysine-specific histone demethylase 1A 1 0.659
1e1n FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.658
2pd7 FADVivid PAS protein VVD / 0.658
4fwf FADLysine-specific histone demethylase 1B 1 0.658
4fwj FADLysine-specific histone demethylase 1B 1 0.658
1joa FADNADH peroxidase 1.11.1.1 0.657
2tmd ADPTrimethylamine dehydrogenase 1.5.8.2 0.657
3m12 FADMonomeric sarcosine oxidase 1.5.3.1 0.657
4m52 FADDihydrolipoyl dehydrogenase 1.8.1.4 0.657
1ebd FADDihydrolipoyl dehydrogenase 1.8.1.4 0.656
1mxt FAECholesterol oxidase 1.1.3.6 0.656
3qow SAMHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.656
5j4e FMNSensory box protein / 0.656
1mgo NADAlcohol dehydrogenase E chain 1.1.1.1 0.655
3ic9 FADPutative dihydrolipoamide dehydrogenase / 0.655
4dsh FDAUncharacterized protein / 0.655
4dxh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.655
5kj1 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.655
3bi2 FADPolyamine oxidase FMS1 / 0.654
4xd2 NAIAlcohol dehydrogenase E chain 1.1.1.1 0.654
5cdg NAJAlcohol dehydrogenase E chain 1.1.1.1 0.654
5kcp NAJAlcohol dehydrogenase E chain 1.1.1.1 0.654
1cbo FADCholesterol oxidase 1.1.3.6 0.653
2ylt FADPhenylacetone monooxygenase 1.14.13.92 0.653
4c3y FAD3-ketosteroid dehydrogenase / 0.653
4dsg FADUncharacterized protein / 0.653
4dwv NAJAlcohol dehydrogenase E chain 1.1.1.1 0.653
4nfh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.653
5cds NAJAlcohol dehydrogenase E chain 1.1.1.1 0.653
5kcz NAJAlcohol dehydrogenase E chain 1.1.1.1 0.653
2rgo FADAlpha-Glycerophosphate Oxidase / 0.652
1reo FADL-amino-acid oxidase 1.4.3.2 0.651
1gxf FADTrypanothione reductase 1.8.1.12 0.650
1yqz FADCoenzyme A disulfide reductase / 0.650
4b65 FADL-ornithine N(5)-monooxygenase / 0.650
4eqs FADCoenzyme A disulfide reductase / 0.650
4opd FDAConserved Archaeal protein / 0.650
5hsa FASAlcohol oxidase 1 1.1.3.13 0.650