sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 1.445 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 1.276 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 1.055 | |
| 3o26 | NDP | Salutaridine reductase | / | 1.053 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 1.006 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.978 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.961 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.957 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.952 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.949 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.947 | |
| 4kwh | NAP | Reductase homolog | / | 0.945 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.944 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.944 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.941 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.938 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.934 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.929 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.925 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.921 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.917 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.914 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.912 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.909 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.908 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.907 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.905 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.904 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.903 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.903 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.901 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.901 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.901 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.899 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.898 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.896 | |
| 4qec | NAP | ElxO | / | 0.895 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.894 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.894 | |
| 1sny | NAP | LD36273p | / | 0.892 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.892 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.891 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.891 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.888 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.887 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.887 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.886 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.886 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.881 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.880 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.877 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.875 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.872 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.867 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.863 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.862 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.860 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.859 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.855 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.855 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.855 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.853 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.852 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.849 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.848 | |
| 3sju | NDP | Keto reductase | / | 0.848 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.846 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.846 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.846 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.845 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.843 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.841 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.836 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.836 | |
| 3mje | NDP | AmphB | / | 0.835 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.833 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.831 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.829 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.829 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.828 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.828 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.827 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.826 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.823 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.821 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.820 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.820 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.816 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.815 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.814 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.814 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.813 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.813 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.812 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.812 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.811 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.810 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.809 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.808 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.808 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.808 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.806 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.805 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.805 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.805 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.804 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.803 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.802 | |
| 4hxy | NDP | Plm1 | / | 0.802 | |
| 1iy8 | NAD | Levodione reductase | / | 0.800 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.799 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.797 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.796 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.796 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.796 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.795 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.793 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.793 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.793 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.792 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.791 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.789 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.789 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.787 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.783 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.782 | |
| 4qed | NAP | ElxO | / | 0.781 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.780 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.777 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.777 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.775 | |
| 4u7w | NDP | MxaA | / | 0.775 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.774 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.772 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.772 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.770 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.770 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.769 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.768 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.766 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.764 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.761 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.760 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.759 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.759 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.759 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.758 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.757 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.757 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.755 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.755 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.753 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.752 | |
| 4clo | NAP | Pteridine reductase | / | 0.752 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.751 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.750 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.749 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.748 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.748 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.746 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.746 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.744 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.743 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.741 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.741 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.740 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.739 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.739 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.738 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.738 | |
| 3bmo | NAP | Pteridine reductase | / | 0.737 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.737 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.736 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.733 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.731 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.730 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.729 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.729 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.727 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.727 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.725 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.724 | |
| 5d2e | NAP | MlnE | / | 0.724 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.723 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.723 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.722 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.721 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.720 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.720 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.717 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.717 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.716 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.715 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.715 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.714 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.714 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.714 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.714 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.713 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.713 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.711 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.710 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.708 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.706 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.705 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.704 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.704 | |
| 3uce | NDP | Dehydrogenase | / | 0.702 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.700 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.700 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.698 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.698 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.698 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.697 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.696 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.696 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.695 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.694 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.694 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.692 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.692 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.692 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.691 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.688 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.688 | |
| 2q0l | NAP | Thioredoxin reductase | 1.8.1.9 | 0.688 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.687 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.686 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.686 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.686 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.686 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.686 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.686 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.686 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.685 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.684 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.683 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.683 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.683 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.683 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.682 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.678 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.678 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.678 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.677 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.677 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.675 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.675 | |
| 5a06 | NDP | Glucose-fructose oxidoreductase | / | 0.675 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.674 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.673 | |
| 2c3c | NAP | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.672 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.672 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.671 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.671 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.670 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.669 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.669 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.669 | |
| 5a02 | NAP | Glucose-fructose oxidoreductase | / | 0.669 | |
| 3lzx | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.668 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.668 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.667 | |
| 4ccq | NAP | Thioredoxin reductase | / | 0.667 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.666 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.666 | |
| 1i36 | NAP | Conserved protein | / | 0.665 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.665 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.665 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.663 | |
| 2yjz | NAP | Metalloreductase STEAP4 | 1.16.1 | 0.663 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.663 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.661 | |
| 5a04 | NDP | Glucose-fructose oxidoreductase | / | 0.661 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.660 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.660 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.658 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.658 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.657 | |
| 3fsy | SCA | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase | / | 0.657 | |
| 1q0q | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.656 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.656 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.656 | |
| 4b8w | GDP | GDP-L-fucose synthase | 1.1.1.271 | 0.656 | |
| 5cku | NAP | L-ornithine N(5)-monooxygenase | / | 0.655 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.654 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.654 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.653 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.653 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.653 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.652 | |
| 3kbo | NDP | Glyoxylate/hydroxypyruvate reductase A | / | 0.652 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.651 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.651 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.651 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.651 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.651 | |
| 4xb2 | NDP | 319aa long hypothetical homoserine dehydrogenase | / | 0.651 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.650 |