Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4xsd UMP Thymidylate synthase 2.1.1.45

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4xsd UMPThymidylate synthase 2.1.1.45 0.874
4dpd UMPBifunctional dihydrofolate reductase-thymidylate synthase / 0.726
2g8d UMPThymidylate synthase / 0.688
4dq1 UMPThymidylate synthase / 0.685
1njc DCMThymidylate synthase / 0.682
2g86 UMPThymidylate synthase / 0.676
1f28 UMPThymidylate synthase 2.1.1.45 0.672
1j3j UMPBifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.669
4e5o UMPThymidylate synthase 2.1.1.45 0.669
1b5e DCMDeoxycytidylate 5-hydroxymethyltransferase 2.1.2.8 0.664
4isk UMPThymidylate synthase / 0.664
5by6 UMPThymidylate synthase / 0.663
3dg8 UMPBifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.662
4ein NOHThymidylate synthase 2.1.1.45 0.661
4eil UMPBifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.659
2g8a UMPThymidylate synthase / 0.655
2tdm UMPThymidylate synthase / 0.654