sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 1.108 | |
| 4xpd | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.850 | |
| 3s6f | COA | Uncharacterized protein | / | 0.799 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.797 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.781 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.774 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.764 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.762 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.760 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.755 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.755 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.753 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.742 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.742 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.734 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.733 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.728 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.727 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.727 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.725 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.724 | |
| 2bsw | CAO | Probable acetyltransferase | / | 0.722 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.722 | |
| 5h84 | 1VU | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.716 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.715 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.715 | |
| 4kub | COA | Uncharacterized protein | / | 0.714 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.714 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.713 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.712 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.711 | |
| 1qsn | COA | HAT A1 | / | 0.710 | |
| 1l0c | COT | Serotonin N-acetyltransferase | / | 0.708 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.708 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.708 | |
| 5kf8 | COA | Predicted acetyltransferase | / | 0.701 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.700 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.699 | |
| 2jev | NHQ | Diamine acetyltransferase 1 | / | 0.698 | |
| 1kux | CA3 | Serotonin N-acetyltransferase | / | 0.697 | |
| 1z4r | ACO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.695 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.688 | |
| 1bo4 | COA | Aminoglycoside-(3)-N-acetyltransferase | / | 0.687 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.687 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.686 | |
| 4crz | ACO | PanD regulatory factor | / | 0.686 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.685 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.685 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.683 | |
| 1pu9 | COA | HAT A1 | / | 0.680 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.679 | |
| 2vez | ACO | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.678 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.676 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.676 | |
| 5kf1 | COA | Predicted acetyltransferase | / | 0.675 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.673 | |
| 4ua3 | COA | N-alpha-acetyltransferase 40 | 2.3.1 | 0.673 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.672 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.672 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.672 | |
| 2zw5 | COA | Bleomycin acetyltransferase | / | 0.668 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.668 | |
| 1pua | COA | HAT A1 | / | 0.667 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.667 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.667 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.666 | |
| 4jxr | ACO | Acetyltransferase | / | 0.665 | |
| 5h86 | BCO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.665 | |
| 1m1d | LYX | HAT A1 | / | 0.664 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.663 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.663 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.662 | |
| 2prb | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.657 | |
| 2wpw | ACO | Orf14 | / | 0.657 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.656 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.655 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.654 | |
| 1qsr | ACO | HAT A1 | / | 0.653 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.653 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.653 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.652 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.650 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.650 |